Citicoline sodium akhoza kumapangitsanso ntchito ya ubongo tsinde reticular mapangidwe, makamaka kukwera reticular activating dongosolo kugwirizana ndi chikumbumtima cha anthu; kuwonjezera ntchito ya piramidi dongosolo; ziletsa ntchito ya kunja dongosolo chulucho, ndi kulimbikitsa kuchira ntchito ya dongosolo. Zochizira sequelae wa zoopsa ubongo kuvulala ndi ubongo mitsempha ngozi chifukwa cha mantha dongosolo, angagwiritsidwenso ntchito pa matenda a Parkinson, senile dementia ali ndi zotsatirapo; zochizira matenda a mtima ndi cerebrovascular; imakhalanso ndi zotsatira zina zotsutsana ndi ukalamba, kuwongolera kuphunzira ndi kukumbukira.