L-Hydroxyproline ndi chinthu chosafunikira cha amino acid chomwe chimapangidwa panthawi ya kusintha kwa mapuloteni pambuyo pa kumasulira kudzera mu hydroxylation ya amino acid proline ndi enzyme prolyl hydroxylase yomwe imafuna vitamini C monga co-factor. Hydroxyproline ndi gawo lalikulu la mapuloteni collagen ndipo imagwira ntchito yofunika kwambiri pakukhazikika kwa collagen triple helix. Itha kugwiritsidwa ntchito ngati chizindikiro kuti mudziwe kuchuluka kwa collagen. Kuchulukitsa kwa hydroxyproline mumkodzo ndi/kapena seramu nthawi zambiri kumalumikizidwa ndi kuwonongeka kwa minofu yolumikizana. Kuperewera kwa Vitamini C kumachepetsa kutembenuka kwa proline kukhala hydroxyproline, zomwe zimabweretsa kuchepa kwa collagen kukhazikika.L-Ornithine ndi amino acid yomwe imagwira ntchito yofunika kwambiri mu urea. Zimagwira ntchito yofunikira pakutulutsa kwa ammonia nayitrogeni m'thupi. Ili ndi mayina ndi mawonekedwe osiyanasiyana monga L-ornithine ndi aspartate ornithine (OA).