Mankhwala a spermidine ndi C7H19N3, omwe ali ndi gulu limodzi la amine (NH) ndi magulu awiri amino (NH2). Mamolekyu ake akuwonetsedwa pansipa, amtundu wa krustalo wowoneka bwino. Kapangidwe kake ka spermidine kamakhala ndi maatomu atatu a nayitrogeni, omwe amamupangitsa kukhala ndi zinthu zina zamakina ndi zochitika zamoyo.

Spermidine imapezeka muzakudya zambiri, makamaka muzakudya zambiri za nyemba (monga soya), mbewu zonse, zakudya zofufumitsa (monga tchizi), bowa, ndi zipatso zina (monga zipatso za citrus). Thupi limapanganso spermidine palokha, makamaka m'chiwindi, impso ndi matumbo aang'ono. Komabe, kuchuluka kwa spermidine opangidwa ndi thupi la munthu amakhudzidwa ndi zaka, zakudya, matumbo microbiota ndi majini zinthu, ndi kuchuluka kwa kaphatikizidwe thupi la munthu amayamba kuchepa pambuyo zaka 30, ndipo kuchepa ndi zoonekeratu pambuyo zaka 40.

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Spermidine ali ndi anti-oxidation (omveka bwino ma radicals aulere), odana ndi ukalamba (autophagy, kuyeretsa maselo a senescent), kusintha thanzi la ubereki (makamaka kusintha thumba losunga mazira, kutalika kwa zaka zobereka) komanso kuteteza mtima ndi cerebrovascular, etc., wakhala chinthu cha nyenyezi m'munda wa anti-kukalamba.

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Spermidine ili ndi njira ziwiri zochotsera zomera ndi kuwira kwachilengedwe, mankhwala a spermidine pamsika amachokera ku mpunga kapena nyongolosi ya tirigu monga zopangira, ndipo mtengo wa 98% wazinthu zoyera ndi wokwera kwambiri mpaka 7000 yuan / kg.

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Biosynthesis: kaphatikizidwe spermidine ndi homoserine ndi putrescine (butylenediamine) monga gawo lapansi, dehydrogenating homoserine kuti aspartate hemialdehyde ndi NADH ndi homoserine dehydrogenase, synthesizing aspartate hemialdehyde ndi putrescine ku carboxyglarine ndi NADH monga coenzyme, ndi kukwaniritsa regeneration. Pomaliza, arginine decarboxylase decarboxylated arginine kupanga arginine. Kuchuluka kwa spermidine mu njira yothetsera kungakhale pafupifupi 13g/L.

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Pakalipano, makampani opanga zamoyo zapakhomo Huarui Biology, Zhongke Xinyang, Twinings Biology ndi Shanghai ergothione ndi makampani ena akukankhira mankhwala a biology spermidine, omwe pamapeto pake amatha kutsogolera mafakitale ndikukhala operekera ambiri tiyeni tidikire ndikuwona.