(1) Zinthu zamoyo zomwe zimachitika mwachibadwa

Monga monosaccharate yachilengedwe, mannose adapezeka mu epidermis ya maapulo (0.7-1.2%) ndi malalanje (0.3-0.8%). Mapangidwe ake a molekyulu anali ?. C?H??O? ndi glucose ?. 8 . Panthawi ya metabolism yaumunthu, mannose amalowa m'maselo kudzera pa chotengera china, GLUT1, koma sichiyambitsa njira yopangira insulini, chinthu chomwe chimapangitsa kukhala chisankho chokoma kwa odwala matenda a shuga 78.

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(2) Kuchuluka kwa zakudya zatsopano

Mu 2023, National Health Commission idalemba kuti konjac mannose oligomeric ngati chakudya chatsopano, zomwe zikuwonetsa kulowetsedwa kwa mannose mugawo lazakudya 7. Mlingo wa polymerization wa mannose oligosaccharide wopezedwa ndi enzymatic hydrolysis wa konjac glucomannan umayendetsedwa mkati mwa mayunitsi a shuga a 2-10, omwe samangokhalabe ndi zinthu zachilengedwe komanso amatha kusintha. 7 yagwiritsidwa ntchito muzakudya zopitilira 20 monga zakumwa zopanda shuga ndi mabisiketi ogwira ntchito.

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Chachiwiri, njira yopatsa thanzi ya mannose

(a) chotchinga chachilengedwe cha dongosolo la mkodzo

Deta yachipatala ikuwonetsa kuti 2g ya mannose patsiku imatha kuchepetsa kuchuluka kwa matenda obwera chifukwa cha mkodzo mwa amayi ndi 38% 8. Dongosolo lake limaphatikizapo:

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chilolezo chathupi : 90% ya kudya imatulutsidwa kudzera mkodzo mkati mwa mphindi 30-60, ndipo mabakiteriya oyambitsa matenda (monga E. coli) amachotsedwa m'thupi 8;

kuwonongeka kwa biofilm : kuwononga β-1, 4-glucoside chomangira cha bakiteriya biofilm, sinthani mphamvu ya mabakiteriya a maantibayotiki katatu kuwirikiza 78;

chitetezo chamthupi : kulimbikitsa chitetezo chamthupi ndi ma cell a urethral epithelial, kukulitsa chitetezo cham'deralo 8.

(2) Wosunga thanzi lamatumbo osawoneka

Konjac mannooligosaccharide imatha kuchulukitsa ma probiotics monga bifidobacterium, ndikuwonjezera kuchuluka kwa m'matumbo ndi 25% 7. Mu mayeso azachipatala pachipatala cha Wuhan Union Medical College Hospital, atamwa mannose oligosigro kwa milungu inayi, kuchuluka kwa matumbo kumawonjezeka kuchoka pa 2.3 mpaka 4.1 pa sabata, ndipo kuchuluka kwa matenda otupa m'mimba kudatsika ndi 62% 7.

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(3) Chida chopewera ndikuwongolera matenda a metabolic

Mosiyana ndi zotsekemera zopanga, mannose ali ndi index ya glycemic (GI) ya 0, ndipo m'malo mwa sucrose muzowotcha adachepetsa kuchuluka kwa shuga wamagazi a postprandial ndi 2.1mmol/L mwa odwala matenda ashuga 78. Kafukufuku wa 2024 Journal of Nutrition adatsimikizira kuti mannose amathandizira kulolerana kwa shuga mwa odwala omwe ali ndi insulin 7 osamva insulin poyambitsa njira ya AMPK.

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3.Njira zatsopano m'makampani azakudya

(1) Zitsanzo za chitukuko cha chakudya chogwira ntchito

Zakumwa zoteteza mkodzo : 500mg/botolo la mannose oligosaccharide linawonjezeredwa ku chakumwa cha cranberry chamtundu wina, ndipo kuchuluka kwa malonda kudaposa milandu 2 miliyoni mchaka choyamba cha 7;

Chophika buledi chowongolera shuga : mkate wolowa m'malo mwa mkate wopangidwa ndi konjac ndi mannose-oligosaccharide uli ndi 45% yamafuta ochepa komanso fiber 7 kuwirikiza katatu;

Kulimbitsa chakudya cha ana : Tchizi zowonjezeredwa ndi mannose zimatha kulimbikitsa mayamwidwe a calcium ndi 18%, omwe aphatikizidwa mu 30% ya chakudya cha ana a sukulu 7.

(2) Kupambana pakukonza luso laukadaulo

Ukadaulo wotsogozedwa wa enzymatic hydrolysis wopangidwa ndi mabizinesi a Hubei wachulukitsa kutembenuka kwa konjac glucomannan kuchoka pa 58% mpaka 92%, ndikuchepetsa mtengo wopanga ndi 40% 7. Kugwiritsa ntchito njira ya microencapsulation kwawonjezera kukhazikika kwa mannose mpaka mphindi 60 pa 120 ℃, ndikukulitsa ntchito yake pantchito yophika 38.

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4.Chidziwitso cha sayansi ndi kugwiritsa ntchito mwanzeru

(1) Lamulo la Chikhalidwe la kuwongolera mlingo

Malo otetezeka: Kudya kamodzi sikudutsa 3g, kudya tsiku ndi tsiku kumayendetsedwa mkati mwa 5g, mopitirira muyeso kungayambitse kutsekula m'mimba, kutsegula m'mimba (pafupifupi 7%) 8;

Chenjezo lapadera la chiwerengero cha anthu: odwala omwe ali ndi vuto la aimpso kuchepa kwa thupi kunatsika ndi 50%, ayenera kugwiritsa ntchito 8 motsogozedwa ndi dokotala;

Synergistic scheme : Kuphatikiza ndi cranberry extract, antibacterial effect yawonjezeka ndi 2.3 times 8.

(2) Chisinthiko chamakampani pazolemba zolembera

Mfundo Zazikulu Zazakudya Zazakudya Zopangira Zakudya Zokonzedweratu monga zasinthidwa mu 2024 zimafuna:

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Mannose adzalembedwa mosiyana m'ndandanda wa zosakaniza ndipo sayenera kusakanikirana ndi mawu akuti "sweetener" 7;

Zolinga za ntchito ziyenera kulembedwa "osati chithandizo chamankhwala china" 8;

Mlingo ≥1g/100g uyenera kulembedwa "kungayambitse kusapeza bwino kwamatumbo" 7.

1.Mikangano ndi ziyembekezo zamtsogolo

(1) Mkangano womwe ulipo

Zotsatira za nthawi yaitali zomwe ziyenera kuwonedwa : zotsatira za nthawi yaitali za kudya kosalekeza kwa zaka zoposa 5 pa zomera za m'mimba sizikuwonekera 7;

Chikhalidwe : Kaya njira ya enzymatic hydrolysis imasintha zofunikira za zinthu zimayambitsa zokambirana zamaphunziro 7;

Zotsatira za Ecological chain : Kukula kwa ulimi wa Konjac kwapangitsa kuti 30% ya malo obzala mbewu asinthe, zomwe zitha kusokoneza zachilengedwe 7.

(2) Chitsogozo cha chitukuko cha zamakono

Kugwiritsa ntchito molondola : Kupanga zotuluka za mannose zamitundu yosiyanasiyana 8;

Kupanga kobiriwira : Mitundu ya Konjac yosinthidwa ndiukadaulo wa CRISPR, zomwe zili mu glucomannan zidakwera kuchoka pa 60% mpaka 85% 7;

Kuwunika mwanzeru : Chida chovala chimawunika kuchuluka kwa mannose mumkodzo munthawi yeniyeni pazowonjezera zamunthu 8.

Mapeto

Monga chitsanzo cha kuphatikizidwa kwa chilengedwe ndi luso lamakono, mannose sikuti amangopitirizabe nzeru zakale pansi pa mtengo wa apulo, komanso amawalitsa kuwala kwa zakudya zamakono zamakono. Motsogozedwa ndi Healthy China 2030 njira, chowonjezera chogwira ntchito komanso chotetezekachi chikukonzanso malire a kumvetsetsa kwa anthu pazowonjezera zazakudya. Komabe, m’pofunika kuzindikira kuti kugwiritsiridwa ntchito mwanzeru kwa chowonjezera chirichonse kuyenera kuzikidwa pa zakudya zopatsa thanzi, monga momwe “Zowonjezera Zakudya Zosape?eka” zimati: “Sayansi ndi luso lazopangapanga zapangitsa chakudya kukhala chotheka, koma kulemekeza chilengedwe ntha?i zonse kwakhala maziko a malonda a chakudya.