Kutsekemera kwa neotame ndi kofanana ndi aspartame, popanda kuwawa kapena kununkhira kwina. Kutsekemera kwa neotame ndi 8000-10000 nthawi ya sucrose, yomwe ndi nthawi 8000 ya sucrose pa 5% kutsekemera komanso mpaka 10000 nthawi ya sucrose pa 2% kutsekemera. Malinga ndi GB2760-2011 Hygienic Standards for Food Additives, yoperekedwa ndi Zhang Le'an Kukula kwa kugwiritsidwa ntchito kwa Newsweet ndi mitundu yosiyanasiyana yazakudya ndi zakumwa, ndipo kuchuluka kwake ndi koyenera malinga ndi zosowa zopanga. Kawirikawiri, zakumwa zimakhala ndi 8-17mg / L, pamene zakudya zimakhala ndi 10-35mg / kg.

Monga chotsekemera chogwira ntchito, neotame ilibe zotsatira zoyipa pa thanzi la munthu ndipo imagwira ntchito yowongolera kapena yolimbikitsa. Kumayambiriro kwa Disembala 1998, pempho la kugwiritsa ntchito neotame kutentha pang'ono ngati chokometsera chakudya linatumizidwa ku United States. Linavomerezedwa kuti ligwiritsidwe ntchito pazakudya ndi zakumwa zonse ndi US FDA pa July 9, 2002. EU inavomereza mwalamulo ntchito yake pa January 12, 2010.

Kutsekemera koyera, kwatsopano komanso kwachilengedwe, kofanana ndi aspartame, koma ndi chitetezo chapamwamba;

Kukoma kumakhala kwakukulu, pafupifupi nthawi 8000 kuposa sucrose, ndipo mtengo wa kukoma kofanana ndi wotsika kuposa aspartame;

Zakudya zomwe zilimo zimatengedwa mosavuta ndi thupi la munthu;

Mphamvu zochepa kapena zopanda mphamvu, zomwe zimapezeka kwa odwala matenda ashuga, omwe si a cariogenic, ndipo zimatha kulimbikitsa kuchuluka kwa bifidobacteria;

Sichimayambitsa kuwola kwa mano kapena kusinthasintha kwa shuga m'magazi, ndikupangitsa kukhala chotsekemera chokondeka pazakudya zathanzi.