Mu 1976, ofufuza ataphunzira zotumphukira za klorini za sucrose, adapeza mwangozi pawiri yokhala ndi kukoma kwambiri, sucralose, yomwe idawonedwa ngati yofunika kwambiri pazakudya zotsekemera, chifukwa sucralose sinali yotsekemera, komanso yokhazikika, yoyenera kugwiritsidwa ntchito muzakudya ndi zakumwa. M'zaka za m'ma 1980, sucralose adayesa mayeso ambiri okhudzana ndi chitetezo, kuphatikiza maphunziro a toxicological ndi mayeso azachipatala, kuwonetsa chitetezo chake mwa anthu pamlingo wovomerezeka, ndipo mu 1991, sucralose idavomerezedwa koyamba ku Canada kuti igwiritsidwe ntchito ngati chowonjezera cha chakudya. United States Food and Drug Administration (FDA) idavomereza sucralose ngati chotsekemera chambiri chazakudya ndi zakumwa, ndikupita patsogolo kwaukadaulo wopanga, mitengo yopangira sucralose imachepetsedwa pang'onopang'ono, ndikupangitsa kuti ikhale yopikisana pamsika, ndipo imagwiritsidwa ntchito kwambiri muzakudya ndi zakumwa. M'zaka zaposachedwa, magawo ogwiritsira ntchito sucralose akulitsidwanso, monga madzi a ndudu ya e-fodya, malo ogulitsa mankhwala, chakudya chogwira ntchito ndi zina zotero. Pakati pawo, ndudu zamagetsi chifukwa cha kutentha kwapadera kwa kutentha, kugwiritsa ntchito sucralose kumasiyananso ndi zakudya zachikhalidwe.

Mkhalidwe wa sucralose mu ndudu za e-fodya

Sucralose, monga chotsekemera chamadzi a ndudu ya e-fodya, ili ndi zabwino zoonekeratu monga kutsekemera mwachangu, kutsekemera kwambiri, komanso kutsekemera kwachilengedwe popanda kusiya kutsekemera. Pa nthawi yomweyi, zovutazo zimakhalanso zodziwika bwino, chiopsezo cha phala pachimake chimakhala chokwera kwambiri, ndipo kuwonongeka kwa kutentha kumatha kuchitika pa kutentha kwakukulu, kupanga zinthu zovulaza, monga hydrogen chloride (HCl) ndi mankhwala a chloral. Kuphatikiza apo, ma chloride ion amatha kulumikizana ndi mawaya otenthetsera zitsulo, zomwe zimatsogolera kumvula yachitsulo cholemera, zomwe zimayambitsa ngozi.

Mu 2015, Lu Xialian (kuwola kwa kutentha kwa sucralose) ndi ena ochokera ku Sun Yat-sen University adagwiritsa ntchito ukadaulo wa TG-DSC-FTIR kuti afufuze momwe sucralose imawola, ndipo zotsatira zake zidawonetsa kuti sucralose iyamba kuwola pa 120 ℃, kupanga HCl, H2O ndi CO2. Popeza zomwe zili muzakudya za sucralose ndizochepa kwambiri, sucralose imayamba kuwola. Hydrochloric chloride yopangidwa ndi kuwonongeka kwake imasungunuka m'madzi ngati hydrochloric acid, yomwe ndi gawo lalikulu la asidi m'mimba, ndipo zitha kuganiziridwa kuti sucralose sipanga zinthu zovulaza mthupi la munthu pansi pa kutentha kwambiri kutentha kosachepera 200 ℃. Chifukwa cha kutentha kwapadera kwa ntchito (> 200 ° C), madzi a ndudu ya e-fodya akadali ndi kusatsimikizika kwakukulu poyerekeza ndi kuphika zakudya zachikhalidwe. Mu 2019, Rachel El-Hage (kutulutsa kwapoizoni komwe kumabwera chifukwa cha sucralose kuwonjezeredwa ku ndudu zamagetsi zamagetsi et al. adagwiritsa ntchito GC-MS kuti azindikire kutulutsa kwa aerosol kwa zakumwa za e-fodya ndi sucralose yowonjezeredwa, ndipo adapeza zakumwa ziwiri za chloropropanol pakutulutsidwa kwa aerosol, ndi kuchuluka kwa chloroprocralose yamadzi yofananira mu Anna chaka chomwecho. K. Duell (Sucralose-Enhanced Degradation of Electronic Cigarette Liquidsduring Vaping) et al adadutsa 1H NMR spectroscopy, ion chromatography ndi gas chromatography pamodzi ndi spectrometry yambiri ndi flame ionization detector anapeza kuti sucralose imayambitsa kupanga ma chlorides omwe angakhale ovulaza kapena caganohydes ang'onoang'ono. acetals pamene atomized.

Mu 2024, ogwira ntchito pamakampani a E-fodya Yan (Kukhudza kwa sucralose ndi neotame pachitetezo cha mpweya wachitsulo mu ndudu zamagetsi ndi sucralose adafanizidwa pakati pa zotsekemera ziwiri, neotame ndi sucralose, pakutulutsidwa kwa zitsulo zolemera kuchokera ku ndudu za e-fodya ndi zotsatira zake pakuchita ma cell. Zinakhudza kwambiri ntchito zama cell Zomwe zimachitika ndi sucralose mu ndudu za e-fodya

Mwachidule, sucralose ndiyokhazikika muzakudya ndipo imakhala ndi chiopsezo chochepa paumoyo. Mu e-fodya yamadzimadzi, sucralose sanganyalanyazidwe pakuwongolera kukoma, zovuta kwakanthawi kusintha, kuopsa kwachitetezo sikunganyalanyazidwe, koma kuyika pambali mlingo wonena za kawopsedwe ndi wankhanza, momwe mungagwiritsire ntchito sucralose momveka bwino. Kuphatikiza apo, pali zambiri zomwe zikusowa, ndipo ndikofunikira kuti mufufuze mosalekeza ndikuwongolera pang'onopang'ono.