Pa HMB, dzina lonse la β-hydroxy-β-methylbutyrate calcium, ndi imodzi mwa mitundu yowonjezera yowonjezera ya HMB (β-hydroxy-β-methylbutyrate). Beta-hydroxy-beta-methylbutyric acid (HMB) imapezeka kwambiri mu zipatso za citrus ndi ndiwo zamasamba monga broccoli, nyemba monga nyemba, nsomba zina ndi nsomba za m'nyanja. β-hydroxy-β-methylbutyrate calcium (Ca HMB) ndi mchere wa calcium wa β-hydroxy-β-methylbutyrate (HMB). Chifukwa yogwira chikhalidwe cha HMB, kuti atsogolere yosungirako ndi ntchito, nthawi zambiri n'kukhala mchere kashiamu pamene synthesizing, ndi chigawo chachikulu HMB zili ranges ku 77-82%.

HMB ndi metabolite wapakatikati wa munthu wofunikira amino acid leucine, ndipo thupi la munthu limatha kupanga pang'ono HMB yokha. Muzakudya zabwinobwino, thupi la munthu limatulutsa pafupifupi 300 mpaka 400 mg patsiku, pomwe 90% imachokera ku catabolism ya leucine. HMB ingagwiritsidwe ntchito kulimbikitsa kukula kwa minofu, kupititsa patsogolo chitetezo cha mthupi, kuchepetsa mafuta m'thupi ndi kuchepa kwa lipoprotein otsika kwambiri m'thupi kuti achepetse kuyambika kwa matenda a mtima ndi matenda a mtima, komanso kupititsa patsogolo luso la kukonza nayitrogeni m'thupi, kusunga mapuloteni m'thupi, komanso kuteteza kuwonongeka kwa minofu kwa odwala omwe ali pabedi kapena olumala. M'zaka zaposachedwa, chifukwa zimatha kuchepetsa kuwonongeka kwa minofu pambuyo pochita masewera olimbitsa thupi, kukonza ulusi wa minofu, kuonjezera mphamvu za minofu ndikuwotcha mafuta a thupi, zakhala chinthu chofunika kwambiri pa masewera olimbitsa thupi. Kuphatikiza apo, HMB yatsimikiziridwa mwachipatala kuti imathandizira machiritso a bala ndikuletsa kutupa. Kafukufuku wasonyeza kuti Ca HMB imatha kufulumizitsa kaphatikizidwe ka mapuloteni ndikuchepetsa kudya kwa mapuloteni. Ca HMB yophatikizidwa ndi glutamine ndi arginine imatha kupititsa patsogolo kusakwanira kwa nayitrogeni kwa odwala ndikuthandizira kuti achire kuvulala ndi opaleshoni.

Mu 2011, Unduna wakale wa Zaumoyo ku China udalengeza kuvomera kwa β-hydroxy-β-methylbutyrate calcium.Pa HMB) monga chakudya chatsopano, kugwiritsa ntchito zakudya zopatsa thanzi zamasewera, chakudya chamankhwala chapadera chamankhwala, kuchuluka kovomerezeka ndi ≤3 magalamu/tsiku. Mu 2017, National Health and Family Planning Commission idalengeza zakukula kwa kuchuluka kwa ntchito za Ca HMB kuchokera pazofunsira ziwiri zoyambirira kufika pa zisanu ndi zinayi, ndipo idalamula mabungwe owunika zaukadaulo kuti aziwunika chitetezo. Kugwiritsiridwa ntchito kwa Ca HMB kunakulitsidwa kuti kuphatikizepo zakumwa, mkaka ndi mkaka, mankhwala a koko, chokoleti ndi chokoleti, maswiti, zinthu zophikidwa, ndi zakudya zapadera za zakudya, ndipo ndalama zovomerezeka zikadali ≤3 g / tsiku, zomwe sizinapitirire mlingo wa anthu odzipereka odzipereka. Ca HMB idadziwika kuti GRAS ndi US Food and Drug Administration mu 1995 ndipo imagwiritsidwa ntchito muzakudya zopatsa thanzi komanso zakudya zapadera. M'zaka 20 zapitazi, Ca HMB yakhala ikugwiritsidwa ntchito kwambiri muzamkaka, chokoleti, zakumwa, mipiringidzo yamagetsi ndi zakudya zina pamsika waku US. Ca HMB ndi zakudya zopangira zakudya zomwe zimaloledwa ndi malamulo a ku Japan, zomwe zingathe kuwonjezeredwa m'madera ambiri monga chakudya wamba, zakudya zamasewera, zakudya zochepetsera thupi, zakudya zokongola, ndi zina zotero. Kwa opanga ndi ogulitsa mankhwala, Ca HMB pakadali pano ndi imodzi mwazinthu zodziwika bwino zathanzi pamsika waku Japan.

HMB imagwiritsidwa ntchito kwambiri muzakumwa zolimba, ndipo zinthu zotere ndizochulukanso pamsika wapadziko lonse lapansi. Mwachitsanzo, Juven adayambitsidwa ndi Abbott kuti alimbikitse kaphatikizidwe ka mapuloteni, Myoplex Muscle Armor yomwe idakhazikitsidwa ndi EAS ku United States, Fracora ya thanzi lazaka zapakati ndi okalamba opangidwa ndi Concord ku Japan, ndi zina zambiri, zonse zimachokera ku HMB monga maziko oyambira. Kwa zakumwa zamadzimadzi za HMB, kugwiritsa ntchito kunyumba kuli koyambirira, koma makampani akunja adagwiritsa ntchito ndipo akupita patsogolo pang'onopang'ono. Mwachitsanzo, masewera chakumwa SUISPO anapezerapo ndi Japanese kampani ISDG, ndi kukongola m'kamwa madzi Floage anapezerapo ndi Japanese Concord. Monga zakudya zatsopano zomwe zingathe kuwonjezeredwa ku zakumwa, HMB ikhoza kuphatikizidwa ndi mapuloteni osiyanasiyana, monga mapuloteni a whey, mapuloteni a mkaka, mapuloteni a whey, ndi mapuloteni a masamba, komanso angagwiritsidwe ntchito ndi mavitamini ndi mineral formulations kuti awonjezere ntchito ya mankhwala. Mkaka wamadzimadzi ndi ufa wa mkaka wokhala ndi HMB ungagwiritsidwe ntchito kwa anthu azaka zapakati ndi okalamba kuti ateteze kuwonongeka kwa minofu, komanso angagwiritsidwe ntchito pa masewera ndi anthu olimba kuti apereke zakudya zowonjezera thanzi la minofu. Kuphatikiza apo, yoghurt ina yogwira ntchito pamsika, kuwonjezera HMB imatha kukweza lingaliro loyambirira lazogulitsa ndikupereka lingaliro la kuchepetsa mafuta ndikusintha mawonekedwe, ndikuwonjezera zopangira zopangira ayisikilimu ndi njira yatsopano ya opanga ambiri akunja ayisikilimu. Kuonjezera zosakaniza za HMB kungathe kulimbikitsa mphamvu ya ayisikilimu pamaziko owonetsetsa kukoma ndi kukoma. Komanso, HMB angagwiritsidwenso ntchito mipiringidzo zakudya ndi maswiti, monga otchuka kwambiri zakudya bala mankhwala ndi Maximuscle, amene amawonjezera 20 magalamu a mapuloteni, 3.4 magalamu a creatine monohydrate ndi 1.6 magalamu a HMB, amene amalengezedwa kuchepetsa kuwonongeka kwa mapuloteni, kumanga minofu pamene kulimbikitsa pambuyo ntchito kuchira. Opanga zakudya pakutaya mafuta akhala akugwiritsa ntchito HMB ku maswiti, monga kampani yaku Japan ISDG yopangidwaHMBmaswiti, omwe ndi maswiti kwa anthu omwe amamanga minofu ndikutaya mafuta.

Monga njira yothandiza yazakudya zopewera komanso kuchiza matenda owopsa a minofu,HMBzatsimikiziridwa ndi maphunziro angapo azachipatala, ndipo HMB yatsimikiziridwa mwachipatala kuti imathandizira machiritso a bala ndikuletsa kutupa. Pakalipano, chitukuko ndi kugwiritsa ntchito kwa HMB m'munda wa chakudya chapakhomo changoyamba kumene, koma ndi kuchotsa zopinga zoyendetsera pakhomo, komanso kukwera ndi kukwezedwa kwa zakudya zosiyanasiyana za HMB pamsika wapadziko lonse, akukhulupirira kuti posachedwapa, HMB idzakhala ndi chiyembekezo chochuluka pazakudya.