Sucralose satenga nawo gawo mu metabolism m'thupi la munthu ndipo samatengeka ndi thupi la munthu. Ndi zero calorific value, sucralose ndi yabwino m'malo mwa odwala matenda ashuga. Idawunikidwa ndikutsimikiziridwa ndi FDA mu 1998. Itha kugwiritsidwa ntchito ngati chotsekemera chapadziko lonse pazakudya zonse, ndipo sichimakhudza kuchuluka kwa shuga m'magazi. Itha kuvomerezedwa ndi odwala matenda ashuga. Kuphatikiza apo, sucralose sagwiritsidwa ntchito ndi mabakiteriya a caries ndipo imatha kuchepetsa kuchuluka kwa asidi opangidwa ndi mabakiteriya amkamwa komanso kumamatira kwa ma cell a streptococcal pamwamba pa mano, ndikusewera bwino gawo la anti caries. Kafukufuku wa zinyama awonetsa kuti sucralose ndi yotetezeka kuti igwiritsidwe ntchito kwa nthawi yayitali pa Mlingo kuwirikiza mazana angapo kuposa momwe anthu amagwiritsira ntchito. Kuyesa kwakanthawi kochitika kwa anthu odzipereka wamba kwawonetsa kuti sucralose ilibe zotsatira zosasinthika paumoyo wamunthu. Pambuyo poyesa chiphaso chachitetezo chanthawi yayitali, US FDA yatsimikizira kuti ndi chowonjezera cha GRAS (chitetezo).

Sucralose yakhala ikugwiritsidwa ntchito kwambiri muzakudya zopitilira 400, kuphatikiza zakumwa zokhala ndi kaboni, zakumwa zoledzeretsa, zakumwa zamzitini, ndiwo zamasamba, zakudya zokazinga ndi sosi, jamu, zowotcha, ayisikilimu, mkaka, chimanga cham'mawa, ndi zotsekemera zatsiku ndi tsiku. Zakumwa zokhala ndi ma calorie otsika ndiye msika waukulu kwambiri wa zotsekemera zopanga, ndipo ogula 87 miliyoni ku United States kokha. Coca Cola ndi PepsiCo motsatizana akhazikitsa zakumwa zokhala ndi ma calorie otsika pogwiritsa ntchito sucralose ngati chotsekemera, chomwe chizikhala cholinga chachikulu pakukweza msika wamtsogolo. Izi mosakayikira zidzakulitsa kufunikira kwa sucralose pamsika.