?.? ??? ?????? ?????? ???? ????????????????? ????????? ?????????

?????? ??????????? ?????? 1956 ??????? ?????? ?????? ???????????????? ?????? ????????? ???????, ???? ?????? ???????? ?????????? ??????? ?????? ????? ??????? ???????????:

• ???? ???:???????? ??? ???? ??? ?????? ?????? ?????? ????? ??????? ???

• ???? ???:??? ???????? ???? ???????? ?????? ??????? ???? ?????????? ??(PET-CT ?????????? ???? ???? ???????? 23% ?????? ?????????)

• 2024 ???????,????????????? NIH ????? "??????????????? ?????" ???? ?? ?????? ?????? ?????? ????? ??????????? ??????

?.? ????? ????? ???????? ?????????

???????? ??????? ???? ???????:

2024 ??????? ????? ?????? 4.7 ?????? ???????? ?????? ???????? (CAGR 12.3%)

???? ???? ?????? ???? ????? ???????????????? ??? ??????? 400% ?????? ??????

??????? ??????? ????????:

???????? ????????? (MMSE ??????? 2.1 ????? ?????? ?????)

??????? ???????? ???? (GOS ?????????????? ?????? 1.5 ?????? ?????? ?????)

??????? ??????: ??????? ???????? ???-????? ??????

?

?.? ?????????? ??????? ??

?????? ?????? ?????? ????: ???????????????? ???????? ?????????? ?????? ??????? ?????? ??? ?????? I: ????????????? ???????????? ????????????????? ???????????? ?????? ??? ?????? IIA: ????????? ???????? ???????? ????????? ????????????????? ???????? (18% ????? ??????) ????? ??? ?????? IIB

?

?.? ?????????? ???????? ?????? ???????

??? ????-???? ?????????????? ????? ?????????? ????????? ?????? 2024 ??????? ?????????? ?? ?????? ????????:

?????????? ??????????? ??? 6 ????? ?????? 1000mg ??????????? ????????? ???????? ?????????? ??????? 7.2 ???? ????????? ???????????3

?????, ???????? ??????? ?? ????? (p=?.??) ??????? ??? ???????? ????? ???????????? ????? ?????????????? ???????? ??????

????? ??????: ?????? ????????

?

?.? ????? ?????? ??????

UK NICE ?????????????: ??? ??????? ?????? ?? ????????? ???? ??????? ?????? ????? ???? ???????? ?????? ?????????? ????? (?????-????????????? ?????? ￡45,000/QALY)

??????? ?????????? **???? ????-????????: ?????? ?????????? ???????? ???????? ???????????? ????? ?????????????? ???????? ????? (p=?.??)

?.? ????????? ???????????? ?????????

????? ???????? ?????? ???????? 2024 ?????????:

????? ?????? ??????????? ????????? ??????? ("?????? ????????"?? "??????????? ??????? ?????" ????? ??????????? ???????)

?? ??????????? ?-????? ??????????? ??????? ???????? ?? 32% ????? ?????????? ?????? ????????? ????? ??????? 70% ?? ????

?????? ??????: ??????????????? ?????? ????

?

?.? ???? ??? ????? ????????

????-???????? ???? ????????? ??????????? ????????? ???? (????? ????????????? ??? ???????, CN202410123456.7)

?????????????? ???????-????? ????????????? (?????? ?????? ???? ????????? ???????????? ?????? ????????? ??? ?????????? ??????? ?????? ?????????)

?

?.? ????????? ???? ?????

??????? ????? ???????? ???????? ??:

CDP-?????????????? ???? ?????????? ???????? (???? ???? ????????? 31% ???) ? ??? ?????? 47% ?????? ??????

????? ?????? ??????? ??????-????? ????

?

?.? ?????????? ?????

???????? ?? ????? ?????? ????????? ??????: ????? ???????? ???, ?????????? ??????????? ???? ??? 62 ?????? ??????? ?????????? ???? ?????? ??????? ?????? 32% ?? 89% ?? ???????

?.? ???? ????? ????-????????

"??????? ??? ???? ??? ????? ????, ????? 300 ???? ?????? ???? ????? ???????? ???????" - ?????? ??? ???? ??????? ????? ?????????? ??????