????????????????????? ???????? ???? ????? ??????? ?????, ??????? ????????????????? ???? ?????? ?????????????????? ???????? ????? ??????? ?????????? ??????? ???????? ????, ??? ?????????? ???????? ???? ??????? ?????? ???????? ?????????, ???????????? ???, ????????, ?????? ?????? ?????????? ??? ??????? ??? ???????? ????? ???? ???????? ???? ???????? ?????? ?????? ?????? ???? ??????????? ?'?, ???? ????? ??????, ???? ????? (???? ???? ??????????? ????????), ?????? ??? ????????

??????????? ????? ???????, ??????????, ??????????? ??? ??????? ?????? ???? ?? ??? ??????????????? ??? ???? ????? ?? ????????? ??????????????? ??? ?????? ???? ?????????????? ?????????? ?? ???? ????? ??? ??????? ??? ?????? ???? ?????????? ????????? ?? ????????? ???????????? ??? ?????????????????? ????????????? ? ??? ????????? ?? ?????????????

??????????? ?? ?????????????????? ?????? ???? ?????? ?????????? ??????? ???????, ???? ?????? ???? ????????? ????? ?????? ????????? ?????????, ?????????? ???????? ???????? ??????? ?????????????????? ???????????? ?????? ?????????? ???????? ??????, ?????????? ????????????, ???? ???????? ??????????? ??? ??? ?????????? ??????????? ???????????, ???? ?????? ???????????? ??? ?????????? ??????????? ???? ?????

??????????????? ???-?????? ????? ?????? ???, ??? ??? ??????? ????????????? ????? ???????????????? ??? ?????? ???????? ?????????????? ???????? ?????? ??????? ???? ????????? ????? ???? ????? ?????? ???????????????? ?????? ??? ????????? ???? ??? ?????? ?????? ?????? ???, ???? ??????????? ???????? ??? ???????? ??????? ???????

???? ????? ??? ???? ???? ???, ??????????? ???????, ?????????? ????????, ???????? ???????? ????, ???????????? ???, ????????, ?????? ?????? ??????????, ??????? ??? ???????? ???? ?????????? ???? ????? ??????? ??? ??? ???? ?????? ??? ??????? ???? ?????????? ???????? ????? ????????, ?????????? ??????-??????? ??????? ?????? ????? ???????: ??????? ????? ?? ??????? ?????????? ?????????? ????? ?????? ??????, ???? ???? ????????? ??? ?????????? ??????? ???? ??????? ??????? ???? ???????? ????? ???, ???? ?????? ????????? ??????? ????? ????? ??????? ???????, ???? ????? ???????? 75% ?? 90% ???? ????? ?? ?????????? ???????? ??????? ???? 35%-40.9%, ???? ??????? ????? ??????? ???, ???? ?????? ?????, ??????? ????? ??? ??????????? ?????? ??? ???????? ????? ?????

?????????? ?????? ??????:

?. ???? ???????, ???????? ???????? ??????? ????? ????????? ??????? ??????? ???? ?????????? ???????? ?? ????-???????? ?????? ???????, ???? ?????????? ?? ??? ?????????? ???????? ??????? ? ??? ??? ????? ????? ?????????? ?????? ?????? [1]?

2. 2009 ???????, ?????? ??????? 4191 ?? ????? ????????? ???????? ??????? ???? ?? ??? ??????? ?????? ??????? ??????????, ??? ??????? ???????? ?? ?????????? ??? ??? ?????????? ?????? ???? ??????? NIHSS ????? ??? BI ??????? citicoline ?????? ???????, ??? ?????????? ?????? ??? ???? ????, ??? ???????? ?????? ???? ???? ????????? ????? ?????? ????? ????-???? ?????? (≧2000mg/???) ?? ?????? ???? ?????????????? ????, ??? ?????????? ?????? ?????? ??? ????????? ???? [2]?

3. ???????? ????????? ???? ?? ???????????, ???????????, ????-????????, ????????-?????????? ?????? ??????? ????? ????? ??? ?? ???????????? ????? ???????? ?????????? ???????? ???? ?? ???????? ??? ????? ?? ????????? ???????? ?????? ??? [3]?

?. ?? ????-?????, ???????, ????????? ?????? ???????? ????????? ?????????? ???????? ???? ??????????? ?????? ?????????? ???????, ??? ??????????? ?????????? ?? ??????????? ?????????? ??????? ???????? ????????? ?????????? ?????????? ?????? ?????? ??????? ??[4]?