?????????? ????? ?????? (ALD), ???? ?????????? ??????? ??????? ?????? ??????? ?? ???? ???, ??????? ?????? ???? ??? ?????? ?????, ???????? ?????????? ?????? ?????, ?????????? ???????????, ?????????? ????? ??????????? ??? ?????????? ???????? ???????????? ?????????? ????????????, ??????? ?????????? ????? ???? ?????? ?????? ??????

????? ?, ??????, ?????? ?????????????? ??? ?????, ????? ??????? ?????????????? ????? ???, ???? ??????? ??? ??????????????? ?????????????? ???? ?? ??? ???????? ????????? ???? ????? ????? ????????? "?????????????? ?????????????? ??? ????????? ?????? ??????????????" ?????????? "??????? ????? ?????????? ???? ???? ???????? ??? ???" ?????? ?? ??????? ?????? ????????

??????? ????? ??????? ????? ????? ??????????? B. accidifaciens ? ???????? ?????? ????? ??? ???????-??????? ???? ?????? ????? ????? ????????

??? ?????????? ????, B.accifaciens ????? ??????? ?????????????? ??????? (BSH) ???????? ????? ????? ???????????? ????????? ???? ????????????? ????? ????? ?????? ????????? FXR-FGF15 ???? ?????? ???, ??????? ???? ????????? ??????? ???, ???????????? ?????????? ?????????????????? (OAT) ? ????????? ??????????? ???, ??? ?????? ?????? ??????? ?????????? ? ?????????? ?? ???????????? ?? ??????????? ???? ???? ????????? ???? ???????? ???????? ??? ???? ??? ????? ????? ???????

??? ????????, ????????? ?????? ?? ???? ?????? ?????????? ???? ????? ??????? ??????? ??? ??????? ??? ???????? ????? ????? ??????? ??? ??????? ?????? ?????????? ???? ??? ???? ????? ?????? ?????? ???????? ????????

??????? ???????? ?? ??????? ????? ????? ?????????????? ??????? ?????? ????????? ???? ????? ????????? ?????? ?????, ???????? ???? ?????????? ????? ????? ??? ???? ?????????????? ?????? ??? ??? ?????? ????? ????? ???????????, ???????? ???????? ????? ?????? ????? ?????????????? ?????? ??????????

???? ????? ????? ???????? ??????????????? ?????????????? ????? ???????? ???????, ????????? ????? ???????? ???????? ?? ???????????? ???? ????? ?????? ????????????? ????????? ???? ???????? ???????? ????????????? ???? ???? ?? ??????

????????? ???, ??? ???????? ?? ???????? ??????? ????? ????? ??????? ?????????? ????????????? ????????? ????? ?????? ????? ???????? ?????????????????? (ALT) ??? ??????????? ?????????????????? (AST) ???? ????? ???????, ???????? ???? ?????????? ??? ?????? ???? ????? ???????, ???? ????? ??? ?? ??????? ????? ????? ??????? ?????????????? ????? ???????? ??? ALD ??????? ???????? ????????

???????? ???????? ?? ??????? ????? ????? ??????? ???? ???? ???? ?????? ???? ??? ??????????, ???? ?????????? ??? ???????? ????? ???????, ??? ?????? ?????? ???? ??? ??????????? ????? ???? ????? ???????, ???? ??????? ???? ???? ???????? ??? ?????????? ??????? ????? ?????? ?????????????? ???????? ?????? ????????

??? ??? ????? ?????????????? ?? ???????????? ???????? ???????? 25-30 ????? ?????? ??’???? ???? ????? ????? ??????? ??????? ??????, ?????? ??????? ??? ????? ??????? ???? ?????? ?????? ????, ?? ??? ???????? ????? ?????? ?????? ???? ??? ???????? ???????? ??????? ???? ?????? ????? ????????

?????????, ??????????? ????? ??? ?? ??????? ????? ??????? ????? ????? ???? ???????????? ??????-??????? ???? ?????? ????? ???????? ??? ??????? ????? ????????? ??????? ????????? ??? ??????? ???? ?????????? ????? ??? ??????? ??????? ????

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