???????? ?????? ????? ???????????? ????? ??? ???????? ??? ?????? ??????? ????????, ??? ???? ??????? ????????, ?????, ???? ?????? ???????? (????? 1)? ??? ???????? ????? ?? ???????? ???? ?????????? ?????????? ???? ???????? ???????????? ????? ???????????? ?????? ????? ???? ?? ??? ????? ??? ???, ??????? ??? ??????????? ????? ??????? ?????-????????? ???? ??? ???????, ??? ????? ???? β-??????? ??? ???, ???? ??????????? (Gln) ??? ????????? (Cys) ?? ?????? ?????? ??????? ???????? ????? ?? ????????? ???????? ????? ????? ??? ????? 35 kD, ?????? ???????, ?????? ???????? ??? ?????? ??????, ?????? 70% ?? 80% ?????? ??????? ???????? ???? ??????????????? ????? ????? ???? ????????? ??? ??????, ????? ??????? ?????? ??????? ???? ??-?????? ??????? ??????, ??? ?????? ????? ???????? ??? ?????, ??? ????????? ?????? ?????? ????? ?????????? ???? ?????? ??? ????????? ?????? ??????????? ????, ????????????? ???? ??? ??????????????????? ?????????? ???? ?????? ???????, ?? ???????? ????-???????? ??? ??? ???? ??? pH ????????, ?????? ??????? ?????????????? ????????? ????????????????? ???????? ???? ???? ??? ???? ???????? ???????? ??????????: ????, ????, ???? ??? ?????? ???????? ??????, ???? ?????? ??????? ???????? ????? ???????? ???, ???????? ????? ?????? ??????? ???????? ????? ??????? ???? ????

?