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- ?????? (?????? ??-??????) ?? ??? ????, ?????? ???????? ??? ?????, ?????? ???? ??? ???? ?????? ????? ????? ??? ?????, ??? 90% ?????? ????? ????? ?????? ????? 30 ?? 60 ?????? ??? ??????? ??????? ???????? ?????? ???, ???? ???????? ??? ?????, ?????? ???? ???????? ???????? ??? ?????, ?????? ????????? ??????? ?????? ???? ?????? ???????? ??????????????? ???? ?????? ???????, ????? ????? ???? ???????, ???????? ???????? ????????? ??????? ??? ?????????? ??????????? ???????? ???????? ????????? ???? ?????????? ???????? ???????? ??????? ?? ?????? ??????? ???? ?????????? ???????? ??????? ?????? ??????????????????? ????????????, ?????? ???? ???? ?????? ?????? ??? ??? ?????? ????? ?? ?????? ???????? ???????? ?????????? ????? ?????? ??????? ?? ?????? ???????? ??????? ????? ?? ??? ???? ???????? ???????? ???? ??????? ???? ??????? ?????? ??????? ?????? ???, ??????? ?????, ????????, ????????, ???????? ???????, ?????? ???????? ??????? ???????? ???????? ??? ???????? ?????? ???????? ??????? ????? ??? ???????? ?????? ??????? ???????? ????, ??????????? ??????? ??????????? ???????? ???????? ???????? ???? ???? ???????? ???????? ?? ??????????? ??????? ?????? ???????? ??????? ????? ???????? 50 ??????? ??? ??? ???????? ?????? ?????? ?? ?????????? ??? ????? ???? ?????? ???????? ????????? ?????, ???????? ???????? ???????? ???? ??????????? ??? ?????????? ?????? ??????? ???????????? ?????????? ????????????, ???????? ???????? ??? ????????? ???????? ???????? ??????? ???? ?????? ?????? ????, ???????? ???????? ?????????? ???????? ?????? ???? ???? ?????????? ???? ?????? ?????? ???????????? ????? ??? ???????????? ?????, ???????? ??? ???????? ???????? ?????? ???, ?????? ????????? ???? ???? ??????? ?????? ??????? ?????? ??? ???????? ???? ??????, ???? ???? ?????? ???????? ??? ???????? ????????? ???? ???? ??????? ?????? ???, ?????? ???????? ???? ????? ???, ??? ???? ?????? ???????? ???? ???? ???? ?????????? ????? ?????? ?????? ??????? ?????? ??????? ??????? ???????? ??????? ?????????????? Escherichia coli (UPEC) ?????? ??????? UPEC FimH ???????? ???????? ???????? ?????? ?????????? ??????? ?????? ???? ????????? ??? ??????? ?????? ????? ??? ??? ?????? ?????? ????????? (M4284) ????? ???? ?????? ?????????? ??????? FimH ???????? ???? ???? ??????? ?????? ??????? 100,000 ??? ????, ?????? ??? ????????? ??????? ???? ??? ????? ??? ????????? E. coli ???? ?????? ???????????? ?????? ?? ??????????? ????????, ???? ???????? ?? ??? ???? ?????? ???????, ????????? ??????? ????????? ????? ??? ?????????? ?????? ?????????? ??????? ???????? ????? ?????????? ????????? ?????? ????????? ???????? ??????????? ???????? ????????? ?????? ????, ????????? ??????????? ????? ???????? ?????? ???????, ????????? ?????? ?????? ???? ???? ???????, ????????? ?????? ???? ??? ?????? ?????? ??????? ?????, ?? ??? ?????? ???????????? ????? ?.? ???????, ????????? ??????? ??.? ??????? ???????? ????????? ??? ??????????? ?????????? ?? ?????? ????? ???????? ???????? ?????????? ?????? ???????? ??? ???????? ???????? ????????????? ?????? ???? ??????????