???????? K3 ?? ???? ???????? ?????? ???

????????? ???????? K3 ?? ???? ???????? ???, ?????? ???????? K ?????? ??????? ???? ????????? ???? ???????? ???? ??????? ???????????? ??? ????????????? ????? ??????????? ???????, ??? ????? ??????????? ?????? ???? ???, ???? ????????? ????? ???????? ????? ????? ???????? K3 ?? ?????? ?????? ????? ?????? ????? ??????? ???????

???? ??????? ??????

?????? ??????

??????

(?) ????? ??????: ?????? ?????? (??? ????????, ????, ????? ???, ???????); ???? ?????? (??? ????, ?????? ???????); ????????????? ??? ?????????? (??? ?? ??, ??? ??????? ?????, ????, ???? ????? ??????? ???? ???????? ????????); ?????? ??? ???? ?????? (??? ?? ????, ????????? ?????, ?? ??? ???????? ???????)?

(?) ????? ??????: ?????? ??? ????????? ????????; ??????? ??? ?????? ????????????; ???????? ????? ??? ??? ???????? ???????? ?????? ??? ?????????; ???? ????, ????? ??? ??? ?????? ? ?????? ??????; ???? ??? ???????? ??????; ??? ?? ????? ?????? ??????? ??????? ????????????? ??????? ????????? ????? ??????? ??????? ????? ?????? ??????? ???? ??? ????? ???? ??? ??????????? ????; ???????? ????????, ??????? ??????? ????

(?) ????? ??????: ????????? ?????, ???????? K, ???????? A, ????? ???????? ??????? ????????? ???????? ???????????

?????????

?????????????

?. ???????? K3 ???? ???? ?????????? ??????? ???, ??? ???????? K3 ?????????????? ?????????? ????? ?????????

?. ???????? K3 ????? ????? ??????????? ?????? ???????? K3 ????? ??? ??????????? ??????? ?? ?????????????? ?????? ??? ?????? ??????????? ???????????? ?? ??????????? ???????

3. ???????? K3 ????????? ??????? ?????? ???, ???? ???????? ?????????????? ?? ??????????? ???????, ???? ???????? ??????? ???????? ???????, ??? ?????? ???? ?????????? ?????? ????????? ????????? ???????

?. ???????? K3 ?? ?????????? ???????? ???? ??????? ??????, ??????? ???? ???????, ??????, ????? ?????????????, ??? ????? ???????? ???????? ?????

?????? ??????????????

??????	???????
??????? ???? ??????????	1. H-NMR: ???? ???? ??????? ???? ???? ?????
	2. HPLC-MS: ????? ???? ??? ???? ????? ????? ??? ??????? ???? ???? ???? ???? ??????? ???????
	3. IR: IR ? ???? ??????? ???? ???? ?????
???????? (HPLC)	≥??.?%
????????? ????????	??????????? ??? ????????	EP/USP/BP ???? ???? ???
	?-??????????? ??? ????????	≤0.10%
	??? ???????????	≤0.50%
?????? ???	EP/USP/BP ???? ???? ???
?????? ????? ?????	≤?.?%
????	≤?.?%
???? ???	≤0.1%
???? ????	≤?? ???????
?????	??.?%~???.?% (EP/USP/BP ???? ???????)
????????????????? ????????
??? ????? ?????? ??????	≤1000cfu/????
???? ??? ?????	≤100cfu/????
?. ?????	?????????
?????????	?????????
???. ???????	?????????