HMB ?????? ?????? ????? ???? ?????? ?? ??? ???????? ?????????? ??, ??? ?????? ???? ??? HMB ?? ??? ???? ???? ????? ???? ?? ???? ??? ??? ?? ????? ????, ?????? ???? ????? ??? ???? 300 ??? 400 ????????? ???? ???? ??, ??? ?????? 90% ?????? ?? ??????????? ??? ????? ??? HMB ?? ????? ?????????? ?? ????? ??? ???????? ???, ????????? ????? ?????, ?????????? ??? ???? ???? ??? ???? ???? ??????????? ?? ???? ??? ????? ?? ???? ?? ???? ?? ??? ?? ??????? ??? ?? ?????? ??? ??? ?? ?????? ?? ???? ??? ????? ?? ???, ?? ???? ?? ????????? ???????? ?????? ??? ?????, ???? ???? ??????? ?? ???? ??? ???? ???? ??? ?????? '?? ?? ??? ?????? ??????? ???? ?????????? ?? ??? ??? ???? ?? ?? ???? ?? ???? ??? ??? ?? ?? ????? ????, ?????? ?? ???? ??? ???? ???????? ????? ?? ?????? ??? ??? ???? ??, ?????????? ?? ??????? ?? ?????? ?? ???? ??, ?????????? ?? ???? ??? ???? ?? ??? ???? ?? ???? ??? ??? ???? ??, ?? ??? ????? ??????? ???? ??? ???? ?????? ?? ??? ??? ?? ??? ?????, HMB ????? ?? ???? ??? ???? ??? ??? ????? ??? ???? ?? ?????? ??? '?? ???? ???? ??? ??????? ?? ?????? ?? ?? Ca HMB ??????? ???????? ??? ???? ?? ???? ?? ??? ??????? ?? ??? ??? ???? ?? ???? ??? ????????? ??? ???????? ?? ??? ??? ?? Ca HMB ??????? ?? ???????? ????????? ?????? ??? ????? ???? ?? ??? ???? ??? ????? ??? ??? ??? ???? ???????? ?????? ???? ???? ???

2011 ????, ??? ?? ????? ???? ??????? ?? β-hydroxy-β-methylbutyrate ???????? (Ca HMB) ??? ??? ???? ???? ???? ???? ???????? ??? ?? ???? ????, ??? ????? ???? ?? ?????, ??????? ?????? ????? ??????? ????, ??????? ???? ????? ≤3 ?????/??? ??? 2017 ????, ??????? ???? ??? ?????? ?????? ?????? ?? Ca HMB ?? ????????? ????? ??? ??? ?? ??????????? ??? ??? ??? ????? ?? ???? ????, ??? ??????? ??????? ??? ?? ???? ??????? ???????? ???????? ??? ?????? ????? Ca HMB ?? ????? ??? ??? ???? ???????, ???? ??? ????? ?????, ???? ?????, ?????? ??? ?????? ?????, ?????, ???? ???? ??? ??????? ?????? ???? ????? ??? ?? ????? ??? ??, ??? ??????? ???? ????? ??? ?? ≤3 ?????/??? ??, ?? ?????? ???????? ?????????? ?? ????? ??? ??? ???? ??? Ca HMB ??? 1995 ???? ???? ??? ??? ???? ?????????????? ????? GRAS ???? ????? ????? ?? ?? ??? ????? ?????? ????? ???? ??? ??????? ??????? ???? ????? ????? ??? ????? 20 ????? ????, Ca HMB ??? ?????? ?????? ???? ????? ???????, ?????? ???????, ??? ???? ???????, ???? ????? ??? ??? ?????? ???? ????? ??? '?? ????? ??? ??? Ca HMB ?????? ?????? ????? ?????? ??? ???? ???? ??? ??, ?????? ?? ?????? ???? ????? ???? ?? ???? ?? ????? ?? ?? ????, ??? ????? ????, ??? ????? ???? ????, ??????? ????, ???? ????? ??????, ??????, ??? ??? ???? ??????? ???? ????? ?????? ???? ??? ???????? ?????? ???? ?? ????? ?? ???? ??? ?????????? ??? ????????? ??, Ca HMB ?????? ???? ?????? ?????? ???? ?? ??? ??????? ???? ???????? ?????? ??? ???