?????????? (??????????, ????), ?????? β-merhydrylethylamine ?? ???? ????? ??, ????? ????????? ?????, ????? ????? 99~100℃, ?????? ???? ????? ????, ???? ??? ?????? ???? ????????, ???? ??????????? ?????? ?? ???? ????? ???????????? ??? ????? ???? ????? ??, ?? ?? ?? ???? ?? ?????? ?? ????? ???? ????? ??? ?? ??????? ???? ??? ????? ??? '?? ????????? ????? ?? ??? ???? ????????? ????? ?????? ??? ???? ?? ?????????? ???, ???? ??????? ??? ????????? ?? ????? ??, ???? ???? ?????????????? (????????????????????????, CSH) ??? ???? ??? ???? ????? ??? CSH ?????? ??? ????, ???? ?? ?????? '?? ???, ?????? ??????????????????, ??? ?????? '?? ???? ???????, 70.2~70.7℃ ?? ????? ????? ???

CS ??? ???? ?????????????? (CSH) ??? ????????? ???? ???????? ??? ??, ??? ?? ??? ????? ?? ??? ????? ???? ???? ?? ??, ??? ????? ??? ??? ????? ?? ??????? ????????? ?? ?????? ???? ????? ?? ???? ???

????? ?? ??? ????? ????, CSH ??? ?? ??? '?? CA (????????? ??????????????) ??? ???? ???? ????? ???

logP ???? ???????? ?? ?? ????????? ?????????????? (CA) ????????? ?? ??? ????? ?? ???? ???????????? ??????? (octamer/microfibril) ?? ???? ??? ????? ???????? ???

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

????????? ?????????????? (CA) ?? ?????? ?????? ???????????? ???? ????? ??? ????? ??, ?? ?? ?? ?????? ??????? ???? ????? ?????? ?????? ???????? ??? ???????????? ???? ?? ??? ???????? ?? ???? ??? PH ??? ??? ???????? ?? ???????, ????????? ?????????????? (CA) ???????? ????? ?? ????? ??? ?? ?? ??? ???? ????? ?? ?? ?? ????? ???? ???? ?? ??? ??? ?? ?????? ???? ????? ??, ??? ???? ?????? ???? ??? ??? ???????? ???? ????????? ?????????????? ??? ?? ??? 5 ???? ?? ??? ????? 15 ?????? ?? ???????????? ???? ?? ????? ?? ?????? ?? ????? ???

?????????? ?????????????? ??? ??????? ?????? ?? ??? ???? ????????? ?????? ??? ?? ??? ?? ??? ???? ??????? ??? ???? ??, ?? ????? ?? ????? ?? ?????????? ???? ???? ?????? ???????? ??? ?? ???? ???? ???? ?????? ??? ??? ?????? ??????? ??, ????? ?? ??????? ??? ??? ???? ????-????? ???? ??? ???? ??, ????? ?? ???? ??? ??? ???? ??, ??? ?? ????? ?? ?????? ??? ?????? ???? ?? ????

??? ?? ???????? ???? ?????????? ?????????????? ???, ???? ???? ??? ??? ???? ??????????? ???? ?????? ???? ??, ??? ????? ?? ??????? ??? ????? ???? ??????????? ???? ??????, ????? ?? ??? ??? ????? ??? ??? ????? ?? ????? ?? ???????, ???? ????? ?? ?? ?? ?? ??? ????? ??? ???? ??? ?????? ????? ??, ??? ??? ?? ?????? ?????? ??? ???? ???? ??? ???? ???? ????? ???