?????????? ?????????? ??, ??? ???? ??????? ?? ??? ??? ??? ??????? ?? ??? ??? ????? ?? ?? ??? ?????-1, 2-????????? ???? ????? ????? ????? ??? ???? ??? ???? ???????? ???? ??? ???????? ??, ??? ?? ???? ???? ??? ??????? ????? ??? ??????? ???? ??, ????? ?? ????? ??? ???????????

??????? ???? ??? '?? ?????? ??? ????? ??, ??????? ?????? ?? ??? ?? ???? ??? ????? ??? ??? ??? ???? ?? ??? ??? ??? ??, ??????? ??????? ?????? ??? ?? ?????????, ????????, ??????????????? ??? ??? ??????????? ?? ??? ??? ????? ??? ????? ???

?? ??? ?? ????? ??????? ?????? ??? ??? ?? ????, ??????? ???? ??? ??? ???? ???????, ????? ?? ???? ?? ?????, ??????, ??????, ??? ??? ??? ????? ?????? ?? ???? ???

????????, ?????? ?? ??? '?? ???????? ???? ????? ??, ??? ???? ?? ???? ????? ?? ??? ???? ??? ?????? ???? ?? ??? ??? ????? ??? 1976 ????, ???????? ???? ????? ??? ???? ?????????? ????? ????? ??? '?? ??? ???? ???? ?? ????? ????? ??? ?????? ???? ??? ??, ??? 1988 ???? ????? ?????? ???? ?????? ??? ??, ?? ?? ???? ??? ???? ???????? ???? ???? ??? ???????? ????? ???

???????? ??? ????? ????????? ????? ?? ?? ???? ???? ???? ?????? ???????? ????? ??, ????? ?????????? 20 ????? ??????? ?????? '?? ???? ???? 28.2 ?????/100 ??.??. ????? ??? ?? ???? ???? ????, ??? ????? ??? ??? ??????? ???? ???????????? ??? ???????? ??? ?? ?????? ?? ???????? ??????? ???? ????? ??? ??, ????? ?? ???? ???? ??????? ????, ????? ???? ??????? ???? (????? ???? ????), ?????????????? ???? (??????? ?????? ????), ???????? ????, ???????????? ????? ??????? ???? ????, ???????? ?? ????? ??? ???? ???????, ????? ???????, ???? ???? ??? ??????? ???? ???? ????? ???

???????

(1) ?????
??????? ??? ?? ??? '?? ????? ??? ???? ????? ????? ??, ??? ???? ????? ??? ??????? ???? ??, ?????? ?? ??? '?? 1.0 (???? ???? ????? ?? ???? ??) ???? ????????? ???? ????? ??? ???? ????? ???????? ??? ??, ?? ???? ?? ?????? ????? ?????? ?? ???? ??, ??? ????? ?? ??????? ?????, ????? ?? ????? ??? ???????? ???? ????? ?? ??? ?????-?????? ???? ???
???????? ???? ????? ????? ??, ???????? ????? 400-800 ???? ?????? ???? ???? ?? ?? ???????? ?? ???? ??? ????? ?? ????? ???? ?? ???? ????? ???? ???????? ????? ????? ?????? ???? ?? ???? ??? ?????? ????, ??? ???? ??????? ?? ?????? ????, ??? ???? ????? ??? ????? ????? ????? ?? ?????? ????? ???? ???????? ?? ????? ???? ?? ???? ???

(2) ????
??????? ?????? ???? ?? ???? ?????? ?? ???? ??, ??? ?????? ???? ???? ???? ????? ??????? ??? ???? ?????? ????????? ??? ?????? ???? ?? ???? ?? ??? ?? ???? 4 ????? ?????? ???? ?? ???? ???? ???? ??????? ??? ?????? ???? ??, ??? ????? ???? ????? ???? ??????? ??? ??????? ???? ???????????? ???? ????? ??, ?? ??? ??? ?? ?????? ???? ??? ?? ????? ??, ?????? ????? ???? ???? ???? ????? ????? ??, ??? ?????? ?? ???????? ???? ????? ????? ???
???????? ???? ??? ?????? ?????? ???? ????? ?????? ?? ???? ?? ???? ??????? ???? ??????? ??? ??? ????? ?? ??? ???????? ?????? ???? ???? ?????? ???? ?????? ??, ???????? ?????? ????? ?? ??? ????? ????? ??? ?? ??????? ??? ???? ?????? ?? ????? ??? ?????? ??? ?? ?????? ????? ??, ????? ?? ????? ?? ????? ??? ???? ????

(3) ???????
??????? ??? ?????? ??? '?? ??? ???? ??? ?? ?? ?? ????? ???? ?????? ??? ?? ???????? ??? ???????, ??????? ?? ???? ?????? ??? ?? ???? ????????? ?? ???? ?? ???? ??, ????? ?? ????? ?? ???, ???? ????? ???? ????, ??????, ??? ??? ???? ???? ???? ???? ?? ???-??? ???? ????? ????? ??? ??? ?? ?????? ?????? ???????? ???????? ?? ???? ??? ?? ??? ???? ???
???????? ?? ???? ??????? ??????? ???? ??? ?? ??? ????? ?? ????? ?? ???????? ????? ????? ??? ?????? ????, ??? ?? 1997 ???? ???????? ?? ????? ??? ??????? ??? '?? ??????? ?????, ?????? ??? ??? ??? ???? ?????????????? (FDA), ??????? ??? ????? ?????? (EFSA) ??? ?? ??? ?????? ??? ??????? ?? ???????? ??? ??? ?????? ???? ??????? ????? ???