????? ????? ?? ???? ????? ??? ????? ??? ?????? ???? ???????? ???????, ??? ??? ?? ?????? ????? ???? ?????, ????, ????, ??? ??? (????? 1)? ??? ????? ??? ??????? ?? ?? ????????????? ????????? ?????? ????? ??????????? ?????? ?? ?????????????? ????? ???? ??? ???? ??? ???? ??? ??? ??, ???????? ??, ??? ???????? ???? ???? ?????? ????-????? ??? ???? ???? ??????? ??, ??? ??? ???? ???? ???? β-???? ???? ??, ?? ????????? (Gln) ??? ?????? (Cys) ??? ????? ??? ?????? ???? ???????? ??????? ??? ????????? ??????? ?? ????? ??? ??? ???? 35 kD ??, ???? ???? ???????, ???? ???? ???????? ??? ????????? ??????, ?? 70% ??? 80% ?????? ??? ???? ???????? ??? ?? ???? ???????????? ?? ?? ?? ?? ???? ????? ???????? ??? ?????, ????? ???? ????? ????? ????? ???-????? ???? ???, ??? ?? ???? ??? ??????? ???? ???? ??, ??? ??????? ????? ?????? ??? ????????? ???? ???? ??? ????? ??????? ??? ????????? ??????, ???????????? ??????, ??? ?????????????? ????????? ?????? ????? ?????? ????? ??, ??? ????? ????-????? ???? ????????? ??? ??? pH ?????? ????, ??????-???????? ??????? ??? ????? ?? ??????????????? ????????? ?? ???? ?? ??? ?????? ???? ?????????? ???? ?? ???? ??: ?????, ????, ???? ??? ?????? ????? ??????, ????? ??????-???????? ??????? ???? ?? ??? ??? ????? ????? ??, ???? ?? ????? ??????-???????? ??????? ???? ?? ??? ???? ????? ????? ???

?