Isukari ni ingingo imenyerewe kandi igoye mubuzima bwacu bwa buri munsi. Duhereye kuri sucrose isanzwe, fructose kugeza kuri D-mannose izwi cyane, uyumunsi, tuzavuga kubyerekeranye nurufunguzo ruto ariko rushobora kuba inyenyeri - D-mannose.

D-mannose irashobora kumvikana nkizina ritamenyerewe, ariko mubyukuri ni hexose isanzwe iboneka muri kamere. Bitandukanye na sucrose na fructose, D-mannose iraza mumaso ya rubanda hamwe nuburyohe budasanzwe nibyiza byinshi mubuzima. Uburyohe bwarwo bugera kuri 60% ya sucrose, ni isukari ikora ya calorie nkeya, kugirango ukurikirane indyo yuzuye kubantu ba none, nta gushidikanya ko ari amahitamo meza.

D-mannose ntabwo iryoshye gusa, ariko kandi agaciro kayo karakoreshwa. Mu murima wibiribwa, irashobora gukoreshwa nkibiryo bya karori nkeya kugirango habeho ibiryo bitandukanye byubuzima bwiza; Muri icyo gihe, kubera antioxydants, anti-inflammatory nibindi bintu, nkibikoresho bitanga amazi hamwe nibirwanya gusaza bikoreshwa cyane mumavuta yo kwisiga. Mu rwego rw’ubuvuzi, yerekanye ubushobozi butangaje, kandi ubushakashatsi bwerekanye ko D-mannose ishobora kugabanya indwara zifata amara, kuvura indwara ya rubagimpande, kwirinda indwara ziterwa na asima, ndetse ikanerekana umusaruro mwiza mu kuvura kanseri n’indwara ya glycosylation ivuka.

Mu myaka yashize, hamwe niterambere ryihuse ryibinyabuzima, uburyo bwibinyabuzima bwagiye buhinduka uburyo nyamukuru bwo gukora D-mannose. Ubu buryo bukoresha imisemburo ya biologiya kugirango ihagarike reaction yo guhindura andi masukari (nka D-fructose) muri D-mannose, ifite ibyiza byo gukora neza, kurengera ibidukikije nigiciro gito.

Muri enzymes nyinshi zibinyabuzima, D-mannose isomerase itoneshwa kubera ubushobozi bwayo bwa catalitiki. Nyamara, ibyinshi mubushakashatsi bwambere bwakoresheje Escherichia coli nka selile ya chassis kugirango ikore, ibyo bikaba byateje imbere umusaruro ariko bikazana ingaruka z'umutekano. N'ubundi kandi, E. coli ntabwo ari ibiryo byangiza ibiryo, kandi imiti itanga bitera ibyago byo kwanduza endotoxine. Kugira ngo iki kibazo gikemuke, abahanga batangiye gushakisha ubundi buryo butekanye. Ubwanyuma, bahisemo Bacillus subtilis nkakagari gashya ka chassis. Bacillus subtilis yakunze abantu benshi kubera ibiranga antibacterial idafite uburozi, itagira ingaruka, ikora neza, ntibyoroshye kuguma kandi ntibyoroshye kubyara imiti. Icy'ingenzi kurushaho, byamenyekanye cyane nk "" Muri rusange bizwi ko bifite umutekano "(GRAS) byujuje ibisabwa by’isuku mu biribwa.