Abantu barenga miliyoni 500 ku isi barwaye diyabete, 90% muri bo bafite diyabete yo mu bwoko bwa 2. Abarwayi bakeneye kugenzura ihindagurika ryisukari mu maraso ubuzima bwabo, kandi isukari gakondo (nka sucrose na fructose) yashyizwe ku rutonde rw’imirire mibi kuko itera isukari mu maraso kuzamuka. Nyamara, ibyifuzo bya physiologique byabantu kubiryoheye biragoye kubikuraho, kandi ibicuruzwa bisimbuza isukari byaje kubaho. Sucralose, nk'igisekuru cya kane kiryoha, yakwegereye abantu benshi kubera "zeru zeru hamwe nuburyohe bwinshi" 13.

2. Ibiranga metabolike n'umutekano wa sucralose
1. Ibyiza byo guhinduranya
Imiterere ya molekuline ya sucralose ihindurwa na chlorine, itabora na enzymes zabantu. Hafi ya 85% ya sucralose isohoka mu buryo butaziguye binyuze mu mara nyuma yo gufatwa, naho 15% isigaye ihindurwamo ibintu bitarimo uburozi n'umwijima bigasohoka mu nkari. Ubuvuzi bwa Clinical bwemeje ko indangagaciro ya glycemic ari 0, kandi nta sano ihari ijyanye no gusohora insuline ?12. Kurugero, igeragezwa ryagenzuwe na 2024 ryakozwe n’ishyirahamwe mpuzamahanga rya diyabete (IDF) ryerekanye ko nta mpinduka nini yagaragaye mu kwiyiriza ubusa glucose n’amaraso ya A1C ku barwayi 50 barwaye diyabete yo mu bwoko bwa 2 banywa ibinyobwa bya sucralose mu minsi 30 ikurikiranye ?5.

2. Isesengura ryibiganiro byamakimbirane yumutekano
Nubwo ubushakashatsi bwibanze bushigikira umutekano wabwo, haracyari impungenge kubyerekeye ingaruka zishobora kubaho:

Ingaruka ya microbiota ?: Ubushakashatsi bwakozwe mu 2024 bwasohotse muri Kamere Microbiology bwerekanye ko gufata buri munsi ibirenga 15g bya sucralose byabujije ibikorwa bya porotiyotike nka bifidobacterium, bigatuma kugabanuka kwa 20% -30% kugabanuka kwa mikorobe itandukanye 37;
Imikoreshereze yimiti ?: Iyo ihujwe na anticagulant warfarin, sucralose irashobora kugabanya ibiyobyabwenge bioavailable 12% -15%. 27 igomba gufatwa amasaha 2 atandukanye;
?
gutunganya ibicuruzwa biva mu mahanga:
Icya gatatu, ingamba zubumenyi zo gusimbuza isukari
1. Kugenzura ibipimo byahujwe nibibera
Ishami ry'Umuryango w'Abibumbye ryita ku Buzima (OMS) rirasaba ko abantu barwaye diyabete batarenza 9mg / kg ya sucralose buri munsi (hafi 540mg ku muntu mukuru 60 kg). Scenarios igomba gutandukanywa mubikorwa bifatika:

Kunywa ibinyobwa ?: 300ml ikinyobwa cyibiryo kirimo 30mg sucralose, ni 5.5% gusa byurugero rwumutekano ?16;
Ibicuruzwa bitetse ?: Hitamo imigati ikozwe nubushyuhe buke (2. Gucunga neza imirire
Abasimbuye isukari ntabwo basimbuye kugenzura isukari muri rusange:

Imirire yuzuye ?: Huza ibinyampeke byose (GI munsi ya 55) na fibre yibiryo (25-30g kumunsi) kugirango utinde kwinjiza glucose 46;
Gukurikirana glucose yamaraso:
4. Amahame yinganda no kwigisha abaguzi
1. Ibipimo byerekana ibiryo
Ivugururwa ry’amategeko rusange y’Ubushinwa agenga imirire y’ibiribwa byateguwe mu 2025 bisaba ko ibiryo birimo sucralose bigomba gushyirwaho ikimenyetso kiburira ngo "Abarwayi ba diyabete bakeneye kugenzura ibyuzuye bya karubone" kandi bikerekana ibyongeweho (mg / 100g) 24.

2. Igisubizo cy'akajagari ku isoko
Mu 2024, Ubuyobozi Bukuru bw’Ubugenzuzi bw’isoko bwagaragaje ko 18.7% by’ibicuruzwa "bitarimo isukari" bibika glucose, byerekana ko ari sucralose. Abaguzi bagomba guhitamo ibicuruzwa bifite icyemezo cya SC hamwe na raporo y'ibizamini byuzuye ?78.

5. Icyerekezo cy'iterambere ry'ejo hazaza
1. Guhanga udushya
Mu 2025, Jinhe Industrial yatangije gahunda "yayobowe na chlorine" kugirango igabanye ibisigisigi bya chloropropanol ya sucralose igera kuri 0.01ppm, kandi yongerera igihe cyo kurekura amara hifashishijwe ikoranabuhanga rya microcapsule kugirango igabanye ihungabana rya bagiteri 18.

2. Ubushakashatsi bushingiye ku bimenyetso bushingiye ku bimenyetso
Ishyirahamwe mpuzamahanga rya diyabete ryatangije gahunda y’imyaka 5 yo "gusimbuza isukari na syndrome de metabolike" yo gusuzuma umutekano muremure wa sucralose ku bantu 100.000 barwaye diyabete ?