(1) Mubisanzwe ibintu bibaho mubuzima

Nka monosaccharate isanzwe, mannose yabonetse muri epidermis ya pome (0.7-1.2%) hamwe nicunga (0.3-0.8%). Inzira ya molekuline yari ?. C?H??O? na glucose ?. ?8. Mugihe cya metabolism yabantu, mannose yinjira muri selile ikoresheje transport yihariye, GLUT1, ariko ntabwo ikora sisitemu yo gusohora insuline, umutungo bigatuma ihitamo neza kubarwayi ba diyabete ?78.

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(2) Kuzamuka kw'inyongeramusaruro nshya

Mu 2023, Komisiyo y’ubuzima y’igihugu yashyize ku rutonde konjac mannose oligomeric nk'ibikoresho bishya by’ibiribwa, ibyo bikaba byerekana ko mannose yinjiye ku mugaragaro mu nganda zikoreshwa mu biribwa ?7. Urwego rwa polymerisation ya mannose oligosaccharide yabonetse na hydrolysis ya enzymatique ya konjac glucomannan igenzurwa mubice 2-10 byisukari, ntibigumana umutungo kamere gusa ahubwo bifite nuburyo bwo gutunganya ibintu. ?7 yakoreshejwe muburyo burenga 20 bwibiryo nkibinyobwa bitarimo isukari hamwe na biscuits zikora.

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Icya kabiri, uburyo bwiza bwo guha imbaraga mannose

(a) inzitizi karemano ya sisitemu yinkari

Amavuriro yerekana ko 2g ya mannose kumunsi bishobora kugabanya kwandura indwara zinkari zinkari ku bagore 38% ?8. Uburyo bwibikorwa bukubiyemo:

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? Gukuraho umubiri ?: 90% byo gufata bisohoka muri urethra mu minota 30-60, na bagiteri zitera indwara (nka E. coli) zisohoka mu mubiri ?8;

Gucamo biofilm ?: gusenya bond-1, 4-glucoside ya bagiteri ya biofilm, kunoza imikorere ya bagiteri yica antibiyotike inshuro 3

Amategeko agenga ubudahangarwa ?: guteza imbere ururenda rwa defensine na selile epithelia selile, kongera ubudahangarwa bwaho ?8.

(2) Umurinzi utagaragara w'ubuzima bwo munda

Konjac mannooligosaccharide irashobora kongera porotiyotike nka bifidobacterium, kandi ikongerera ubwinshi bwibimera byo munda 25% ?7. Mu igeragezwa ry’amavuriro mu bitaro bya Wuhan Union Medical College Hospital, nyuma yo gufata mannose oligosigro mu byumweru 4, inshuro zo kwandura amara ziyongereye ziva kuri 2.3 zigera kuri 4.1 mu cyumweru, kandi indwara yo kwaguka mu nda yagabanutseho 62% ?7.

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(3) Igikoresho cyo gukumira no kurwanya indwara ziterwa na metabolike

Bitandukanye no kuryoshya ibihimbano, mannose ifite indangagaciro ya glycemic (GI) ya 0, kandi gusimbuza sucrose mubicuruzwa bitetse byagabanije isukari yamaraso ya postpandandial nyuma ya 2.1mmol / L kubarwayi ba diyabete ?78. Ikinyamakuru 2024 cy’ubushakashatsi ku mirire cyemeje ko mannose iteza imbere glucose yihanganira abarwayi barwanya insuline ?7 ukoresheje inzira ya AMPK.

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3.Imikorere mishya mu nganda zibiribwa

(1) Ingero ziterambere ryibiribwa bikora

Ibinyobwa birinda inkari ?: 500mg / icupa rya mannose oligosaccharide yongewe mubinyobwa bya cranberry complex yikimenyetso runaka, kandi ibicuruzwa byagurishijwe byarengeje miliyoni 2 mugice cyambere cyambere ?7;

? Isukari-igenzura imigati ?: umugati usimbuza ifunguro wakozwe na konjac na mannose-oligosaccharide ifite karubone nkeya 45% hamwe na fibre inshuro eshatu ?7;

? Gukomeza imirire kubana ?: Inkoni za foromaje zongewemo na mannose zishobora kuzamura igipimo cya calcium ku gipimo cya 18%, cyashyizwe muri 30% yo gutanga ibiryo by'incuke ?7.

(2) Iterambere mugutunganya udushya twikoranabuhanga

Ikoreshwa rya hydrolysis ya enzymatique yatejwe imbere ninganda za Hubei ryongereye igipimo cyo guhindura konjac glucomannan kiva kuri 58% kigera kuri 92%, kandi kigabanya igiciro cy’umusaruro 40% ?7. Ikoreshwa rya microencapsulation inzira ryongereye ituze rya mannose kugeza ku minota 60 kuri 120 ℃, kandi ryagura ikoreshwa ryaryo mu guteka ?78.

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4.Ubumenyi bwa siyansi no gushyira mu bikorwa

(1) Amategeko ya Zahabu yo kugenzura ibipimo

? Umutekano ntarengwa:

? Kuburira abaturage bidasanzwe ?: ikibazo cyo kubura impyiko abarwayi basohoka bagabanutseho 50%, bakeneye gukoresha ?8 bayobowe na muganga;

Gahunda ya Synergistic ?: Ufatanije na cranberry extrait, ingaruka za antibacterial ziyongereyeho inshuro 2,3 ?8.

(2) Ubwihindurize bwinganda zerekana ibimenyetso

Amategeko rusange agenga imirire yibiryo byateguwe nkuko byahinduwe muri 2024 bisaba:

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Mannose igomba gushyirwaho ikimenyetso kurutonde rwibigize kandi ntigomba kuvangwa nijambo rusange "uburyohe" ?7;

Imikorere isabwa igomba gushyirwaho ikimenyetso "ntabwo ari ubundi buryo bwo kuvura imiti" ?8;

Umubare ≥1g / 100g ugomba gushyirwaho ikimenyetso "gishobora gutera amara mato" ?7.

1.Impaka n'ibizaza

(1) Intego yibanze yibibazo

Ingaruka z'igihe kirekire zigomba kugaragara ?: ingaruka z'igihe kirekire zo gufata igihe kirekire mu myaka irenga 5 ku bimera byo mu nda ntabwo bisobanutse ?7;

Kamere ?: Niba inzira ya hydrolysis ya enzymatique ihindura imiterere yingenzi yibintu bitera ibiganiro byamasomo ?7;

? Ingaruka z’uruhererekane rw’ibidukikije ?: Kwagura ubuhinzi bwa Konjac byatumye ihinduka rya 30% by’ubutaka bw’ibihingwa gakondo, bushobora kugira ingaruka ku binyabuzima ?7.

(2) Icyerekezo cyiterambere ryikoranabuhanga

? Gukoresha neza ?: Gutezimbere ibikomoka kuri mannose yihariye muburyo butandukanye ?8;

Umusaruro wicyatsi ?: Ubwoko bwa Konjac bwatejwe imbere nikoranabuhanga rya CRISPR, ibirimo glucomannan byiyongereye kuva kuri 60% bigera kuri 85% ?7;

Monitoring Gukurikirana ubwenge ?: Igikoresho cyambara gikurikirana inkari za mannose mugihe nyacyo kugirango wongere wihariye ?8.

Umwanzuro

Nkicyitegererezo cyo guhuza ibidukikije nikoranabuhanga, mannose ntabwo ikomeza ubwenge bwa kera munsi yigiti cya pome, ahubwo inamurikira urumuri rwubuhanga bugezweho. Bayobowe ningamba zubuzima bwiza Ubushinwa 2030, iyi nyongeramusaruro ikora kandi itekanye iravugurura imipaka yabantu bumva inyongeramusaruro. Icyakora, ni ngombwa kumenya ko gukoresha mu buryo bushyize mu gaciro inyongeramusaruro bigomba gushingira ku ndyo yuzuye, kuko "Ibiribwa bidashobora kwirindwa" agira ati: "Ubumenyi n’ikoranabuhanga byatumye ibiryo bishoboka, ariko kubaha ibidukikije byahoze ari ishingiro ry’inganda z’ibiribwa.