Uburyohe bwa neotame burasa nubwa aspartame, nta gusharira cyangwa izindi nyuma. Uburyohe bwa neotame bwikubye inshuro 8000-10000 bwa sucrose, bukubye inshuro 8000 za sucrose kuryoherwa 5% naho inshuro 10000 za sucrose kuri 2%. Ukurikije amahame y’isuku ya GB2760-2011 y’inyongeramusaruro, yatanzwe na Zhang Le'an Ingano yo gukoresha Newsweet ni ubwoko butandukanye bwibiribwa n'ibinyobwa, kandi amafaranga yo gukoresha arakwiriye ukurikije umusaruro ukenewe. Mubisanzwe, ibinyobwa bifite ubunini bwa 8-17mg / L, mugihe ibiribwa bifite ubunini bwa 10-35mg / kg.

Nkibijumba bikora, neotame nta ngaruka mbi igira kubuzima bwabantu kandi igira uruhare runini rwo kugenzura cyangwa kuzamura uruhare. Nko mu Kuboza 1998, gusaba muri Amerika gukoresha ubushyuhe buke bwo gukoresha neotame nk'ibiryoheye ibiryo byatanzwe muri Amerika. Yemejwe gukoreshwa mu biribwa n'ibinyobwa byose na FDA yo muri Amerika ku ya 9 Nyakanga 2002. Umuryango w'ubumwe bw’ibihugu by’Uburayi wemeje ku mugaragaro ku wa 12 Mutarama 2010.

Kuryoshya neza, gushya na karemano, bisa na aspartame, ariko hamwe numutekano mwinshi;

Kuryoshya ni hejuru, inshuro zigera ku 8000 za sucrose, kandi ikiguzi cyo kuryoshya kingana ni gito ugereranije na aspartame;

Intungamubiri zirimo zinjizwa byoroshye n'umubiri w'umuntu;

Ingufu nke cyangwa nta mbaraga, ziboneka kubarwayi ba diyabete, non cariogenic, kandi irashobora guteza imbere ikwirakwizwa rya bifidobacteria;

Ntabwo bizatera kwangirika kw'amenyo cyangwa guhindagurika kw'isukari mu maraso, bigatuma biryoha cyane ibiryo byubuzima.