1. Ibyiza biranga metabolike no kugenzura glucose yamaraso

1. Kalori ya zeru kandi nta bisigisigi bya metabolike
Nyuma yimiterere ya molekuline ya sucralose yahinduwe na chlorine, sisitemu yumubiri yumuntu ntishobora kubora mubisukari byinjira. Amakuru y’ubuvuzi yerekana ko hafi 85% asohoka mu mara nyuma yo gufatwa, naho 15% asigaye akoreshwa n’umwijima mu bintu bitarimo uburozi kandi bigasohoka mu nkari 13. Uyu mutungo uhindura uburyohe bwa "zero calorie", nta mutwaro wongeyeho kubarwayi ba diyabete ku munsi wa buri munsi ufite ibiro 9mg / kg ibiro 28.

2. Uburyo bwamaraso glucose
? nta gutera insuline ?: Ubushakashatsi bwakozwe mu 2024 n’ishyirahamwe mpuzamahanga rya diyabete (IDF) bwerekanye ko sucralose itigeze ikora reseptor T1R2 / T1R3 uburyohe bwa selile ya beta pancreatic beta kandi itigeze itera insuline gusohora ? 57.
Irinde kwinjiza glucose ?: Bitandukanye na sucrose, sucralose ntabwo ibangamira imikorere yabatwara glucose ya SGLT1 mu mara mato, kandi uburyo bwiza bwo kwinjiza glucose bwo mu nda bugumaho kurwego rusanzwe 36. Kurugero, abantu 50 barwaye diyabete yo mu bwoko bwa 2 banywa ibinyobwa birimo sucralose muminsi 30 ikurikiranye bafite ihindagurika ritageze kuri 0.3% murwego rwabo rwa A1c (HbA1c) ?5.
Icya kabiri, agaciro keza ko gucunga imirire

1. Ibishoboka byo gusimbuza isukari gakondo
Uburyohe bwa sucralose bwikubye inshuro 600 ubwiza bwa sucrose, kandi bike cyane birashobora guhaza uburyohe bukenewe. Urugero:

Ongeramo 30mg sucralose kuri 300ml ibinyobwa bitarimo isukari birashobora kugera kuryoshya bihwanye na 10% ya sucrose solution 16;
Ongeramo 15mg kuri buri 100g yifu yibicuruzwa bitetse bigabanya gufata sucrose hafi 45g ?48.

2. Ingaruka yimiterere yimirire
Kugabanya kwishingikiriza kuri karubone ?: Mu gusimbuza karubone nziza, abarwayi ba diyabete barashobora kugabanya buri munsi gufata karubone ya 50-80g, bihwanye no kugabanya karori 200-320kcal ?27;
? Kunoza imirire itandukanye ?: Kongera uburyo bwo kurya indyo ya diyabete hejuru ya 40% mukwemerera kurya neza ibiryo biryoshye cyane nka ice cream na cake 38.
Icya gatatu, ingaruka zo kwirinda ingaruka zubuzima

1. Irinde indwara ya diyabete
Igabanya ibyago byo kurwara amenyo ?: Bagiteri zo mu kanwa ntizishobora gusenya sucralose, kandi imiti irwanya kariesi yagabanije umubare w’ubwandu bwo mu kanwa 27% ku bantu barwaye diyabete ?46;
Kurinda sisitemu yumutima nimiyoboro ?: Nyuma yo gusimbuza sucrose, urugero rwa triglyceride y’abarwayi rwaragabanutse ku kigereranyo cya 0.4mmol / L hamwe na lipoproteine ??(LDL) nkeya cyane byagabanutseho 12% .78.

2. Guhuza n'imiterere idasanzwe
? Ubushyuhe bwo hejuru ?: iyo utetse munsi ya 120 ℃, sucralose ntishobora gutanga uburozi bwibicuruzwa nka chloropropanol, bikwiranye no gukora imigati isukari nke 38;
? Guhuza ibiyobyabwenge ?: ntaho bihuriye nibiyobyabwenge bikoreshwa cyane nka metformine na insuline, ariko bigomba gufatwa nibiyobyabwenge birwanya antifagulant nka warfarin ?27 mugihe cyamasaha 2.
Icya kane, inyungu zo mumitekerereze n'imibereho

1. Kunoza imibereho myiza
Abarwayi ba diyabete bagabanutseho 62% mu guhangayika bitewe no kubura uburyohe no kugereranya amanota 3.2 ku gipimo cyo kwiheba (PHQ-9) amanota 68. Ubushakashatsi bwakozwe ku baguzi 2024 bwerekanye ko kunyurwa n’imirire mu barwayi ba diyabete bakoresheje sucralose nk'isimbura isukari byiyongereye kuva kuri 43% bigera kuri 79% ?3.

2. Kunoza ibiciro byubukungu
Kugabanya amafaranga yo kwivuza kugabanya ?: irashobora kugabanya ikiguzi cyo kuvura buri mwaka ibirenge bya diyabete, retinopathie nizindi ngorane zingana na 3200 yuan / umuntu ?78;
Udushya mu nganda z’ibiribwa ?: Guteza imbere isoko ry’ibiribwa bitarimo isukari kwiyongera 18% buri mwaka kandi biteganijwe ko bizagera kuri miliyari 120 yu 1414 muri 2025.

5. Ibisobanuro birambuye hamwe nibizaza

1. Amahame yo gukoresha siyanse
Igenzura rya Dose ?: Kurikiza OMS yasabye kurenza urugero rwa 9mg / kg uburemere bwumubiri wa buri munsi (hafi 540mg kubantu 60 kg bakuze) 28;
? Gutoranya inzira ?: ibicuruzwa byikoranabuhanga bya microencapsulation byatoranijwe kugirango bigabanye ingaruka ku bimera byo munda (igabanuka ryibikorwa bya bifidobacterium ryaragabanutse kuva kuri 30% kugeza kuri 8%) ?18.

2. Icyerekezo cyiterambere ryikoranabuhanga
Tekinoloji yo kugenzura neza ?: Igikorwa "cyerekanwe na chlorine" cyateguwe na Jinhe Industry mu 2025 kigabanya umubare usigaye wa chloropropanol kugeza 0.01ppm?8;
? Ubushakashatsi bushingiye ku bimenyetso bushingiye ku bimenyetso ?: Ishyirahamwe mpuzamahanga rya diyabete ryatangije ubushakashatsi bw’abantu 100.000 kugira ngo hamenyekane ingaruka ndende za sucralose ku mikorere y’ikirwa ?56.
umwanzuro
Sucralose itanga abarwayi ba diyabete igisubizo kiringaniza uburyohe bukenewe hamwe nubuyobozi bwubuzima. Indangagaciro zingenzi zikubiye muri inertia ya metabolike, guhagarika glucose yamaraso no kwirinda ingorane. Hamwe nogutezimbere umusaruro (nka tekinoroji ya microencapsulation) hamwe nuburyo bunoze bwo kugenzura (nko kuvugurura amabwiriza agenga imirire yubushinwa mubiribwa byateguwe mbere muri 2025), sucralose izaba igikoresho cyizewe kandi cyiza cyo gucunga indyo ya diyabete. Ariko, twakagombye gushimangira ko insimburangingo yisukari idashobora gusimbuza imyanya yibanze yimirire yuzuye hamwe nubuvuzi bwimyitozo ngororamubiri, kandi gukoresha siyanse bigomba gushingira kubuvuzi bwihariye.