Icyayi ni kimwe mu binyobwa bizwi cyane ku isi, cyane cyane mu Bushinwa. Icyayi mu Bushinwa ntabwo ari ikinyobwa gusa, ahubwo ni n'ikimenyetso cy'ubuzima n'umuco.

Kunywa icyayi bifatwa nk'ingeso nziza yo kubaho kuko icyayi kirimo ibintu bitandukanye byingirakamaro, nka catechine, icyayi cya polifenol na cafeyine. Ubushakashatsi bwinshi bwerekanye ko ibishishwa byicyayi bishobora kubuza kanseri, kuramba, kugabanya ibyago byumuvuduko ukabije wamaraso, diyabete, indwara z'umutima nibindi.

Indwara y’umwijima idafite inzoga (NAFLD) ni ubwoko bw’indwara z’umwijima zidakira mu Bushinwa, hamwe n’abarwayi barenga miliyoni 150. Kugeza ubu, nta miti yemerewe kuvura indwara y’umwijima idafite inzoga, kandi abarwayi barashobora kwivanga gusa no guhindura imirire no gukora siporo. Kubwibyo, harakenewe byihutirwa gushyiraho ingamba nshya zo kuvura.

Vuba aha, abashakashatsi bo muri kaminuza y’ubuvuzi y’Ubushinwa basohoye urupapuro rwiswe "Epigallocatechin gallate igabanya indwara y’umwijima y’umwijima utari inzoga" mu kinyamakuru Clinical Nutrition binyuze mu kubuza imvugo n’ibikorwa bya Dipeptide kinase 4 ".

Ubu bushakashatsi bwemeje binyuze mu mavuriro ateganijwe gutegurwa, ubushakashatsi bw’inyamaswa ndetse no mu bushakashatsi bwa vitro ko EGCG, intungamubiri nyamukuru mu cyayi kibisi, ifasha kuzamura umwijima w’amavuta, ECGC ibuza kwirundanya kwa lipide, ikabuza gutwika amavuta, ikabuza kwangirika kw umwijima, kandi igahindura umwijima w’amavuta atari inzoga mu guhagarika imvugo n’ibikorwa bya dipeptidP.

Dipeptide kinase 4 (DPP4), protease ikuramo insimburangingo zitandukanye hejuru y’akagari, yagiye ikusanya ibimenyetso byerekana ko DPP4 igira uruhare mu iterambere rya NAFLD, abarwayi ba NAFLD bagaragaza ibikorwa byinshi bya plasma DPP4 ugereranije n’abantu bafite ubuzima bwiza.

Muri ubu bushakashatsi, abashakashatsi basesenguye ingaruka zishobora kuba EGCG ku barwayi barwaye NAFLD binyuze mu bigeragezo byateganijwe ku mavuriro, bareba iterambere rya EGCG ku mwijima w’imbeba z’icyitegererezo binyuze mu bushakashatsi bw’icyitegererezo cy’inyamaswa, banasesengura uburyo bwo kuzamura EGCG muri NAFLD binyuze mu bushakashatsi bwa vitro.

Mu igeragezwa ry’amavuriro ryateguwe ryitabiriwe n’abitabiriye 15 hamwe na NAFLD, EGCG yakoreshejwe n’ibinini bya polifenol icyayi, kandi amakuru y’umwijima yapimwe ku murongo fatizo, ibyumweru 12, n’ibyumweru 24.

Ibisubizo byagaragaje ko abarwayi bagabanutse cyane ibinure byumwijima nyuma yibyumweru 24 bivurwa na EGCG ugereranije n’ibanze, naho babiri mu barwayi bafite umwijima w’umwijima nyuma y’igihe cyo kuvura ibyumweru 24. Byongeye kandi, kuzenguruka mu rukenyerero rw’abarwayi hamwe na cholesterol yuzuye nabyo byagabanutse cyane nyuma yibyumweru 24.

Isesengura ryerekanye ko nyuma yibyumweru 24 bivura EGCG, urwego rwa AST rwaragabanutse kandi urwego DPP4 narwo rwaragabanutse.

Isesengura ry'imikorere y'impyiko ryerekanye ko serumu creatinine urwego hamwe na glomerular filtration igipimo cyagumye murwego rusanzwe, byerekana ko EGCG ifite umwirondoro mwiza wumutekano.