Ca HMB, izina ryuzuye β-hydroxy-β-methylbutyrate calcium, ni bumwe muburyo busanzwe bwuzuzanya bwa HMB (β-hydroxy-β-methylbutyrate). Beta-hydroxy-beta-methylbutyric aside (HMB) iboneka cyane mu mbuto za citrusi n'imboga zimwe na zimwe nka broccoli, ibinyamisogwe nka alfalfa, n'amafi amwe n'amwe yo mu nyanja. hyd-hydroxy-β-methylbutyrate calcium (Ca HMB) ni umunyu wa calcium ya β-hydroxy-β-methylbutyrate (HMB). Bitewe nuburyo bukora bwa HMB, kugirango byoroherezwe kubika no gukoresha, mubisanzwe bihinduka umunyu wa calcium mugihe cyo guhuza, kandi ibyingenzi bigize HMB biri hagati ya 77-82%.

HMB ni metabolite hagati yigihe cya ngombwa cya aside amine acide yumuntu, kandi umubiri wumuntu urashobora kubyara HMB ubwayo. Mu ndyo isanzwe, umubiri wumuntu utanga mg 300 kugeza 400 mg kumunsi, muri zo 90% zikomoka kuri catabolism ya leucine. HMB irashobora gukoreshwa mugutezimbere imitsi, kongera ubudahangarwa, kugabanya cholesterol hamwe nubunini buke bwa lipoproteine ??mumubiri kugirango igabanye indwara zumutima wumutima nindwara zifata umutima, ariko kandi no kongera ubushobozi bwa azote yumubiri, kugumana proteine ??mumubiri, no kwirinda kwangirika kwimitsi kubarwayi baryamye cyangwa bamugaye. Mu myaka yashize, kubera ko ishobora kugabanya kwangirika kwimitsi yimitsi nyuma yimyitozo ngororamubiri, gusana imitsi yimitsi, kongera imbaraga zimitsi no gutwika amavuta yumubiri, yahindutse inyenyeri mubicuruzwa byimirire ya siporo. Byongeye kandi, HMB yerekanwe mubuvuzi yihutisha gukira ibikomere no kubuza gucana. Ubushakashatsi bwerekanye ko Ca HMB ishobora kwihutisha intungamubiri za poroteyine no kugabanya umuvuduko wa poroteyine. Ca HMB ifatanije na glutamine na arginine birashobora kuzamura uburinganire bwa azote bw’abarwayi kandi bikagira uruhare runini mu gukira ihahamuka no kubagwa.

Mu mwaka wa 2011, uwahoze ari Minisiteri y’ubuzima mu Bushinwa yatangaje ko yemeye calcium-hydroxy-β-methylbutyrate calcium (Ca HMB) nk'ibiryo bishya, gukoresha ibiryo by'imirire ya siporo, ibiryo bidasanzwe byo gukoresha imiti y'ibiryo, amafaranga asabwa ni garama 3 / kumunsi. Muri 2017, Komisiyo y’igihugu ishinzwe ubuzima no kuboneza urubyaro yatangaje ko kwagura ibikorwa bya Ca HMB biva mu byifuzo bibiri byabanje bikagera ku icyenda, kandi hashyirwaho ibigo by’ikoranabuhanga byo gusuzuma ingaruka kugira ngo bisuzume umutekano. Imikoreshereze ya Ca HMB yaguwe ikubiyemo ibinyobwa, amata n’ibikomoka ku mata, ibicuruzwa bya kakao, shokora na shokora, bombo, ibicuruzwa bitetse, n’ibiribwa bidasanzwe by’imirire, kandi amafaranga yasabwaga yari akiri ≤3 g / ku munsi, akaba atarenze urugero rw’abakorerabushake b’ibizamini by’abantu. Ca HMB yamenyekanye nka GRAS n’ikigo cy’Amerika gishinzwe ibiryo n’ibiyobyabwenge mu 1995 kandi ikoreshwa mu biribwa by’imirire y’ubuvuzi ndetse n’imirire idasanzwe. Mu myaka 20 ishize, Ca HMB yakoreshejwe cyane mu bicuruzwa by’amata, ibicuruzwa bya shokora, ibinyobwa, utubari tw’ingufu n’ibindi biribwa ku isoko ry’Amerika. Ca HMB ni ibiribwa bibisi byemewe n’amabwiriza y’Ubuyapani, bishobora kongerwaho mu bice byinshi nk'ibiryo bisanzwe, ibiryo by'imirire ya siporo, ibiryo bigabanya ibiro, ibiryo by'ubwiza, n'ibindi. Birashobora kandi gukoreshwa nk'ibikoresho bikora mu byongera ibiryo nka capsules, ibinini, ibinyobwa bikomeye. Ku bakora na farumasi, Ca HMB kuri ubu ni kimwe mu bintu byubuzima bizwi cyane ku isoko ry’Ubuyapani.

HMB ikoreshwa cyane mubinyobwa bikomeye, kandi ibicuruzwa nkibi nabyo ni byinshi ku isoko mpuzamahanga. Kurugero, Juven yatangijwe na Abbott kugirango iteze imbere intungamubiri za poroteyine, Myoplex Muscle Armor yatangijwe na EAS muri Amerika, Fracora kubuzima bwimitsi yo mu zabukuru ndetse n’abasaza ikorwa na Concord mu Buyapani, nibindi, byose bishingiye kuri HMB nkibikoresho fatizo fatizo. Ku binyobwa bya HMB byamazi, gusaba murugo biri mubyiciro byambere, ariko amasosiyete yamahanga yarayashyize mubikorwa kandi biri mubikorwa byiterambere. Kurugero, ibinyobwa bya siporo SUISPO yatangijwe nisosiyete yAbayapani ISDG, hamwe nubwiza bwo mu kanwa Flowage yatangijwe nu Buyapani Concord. Nkibikoresho bishya byibiryo bishobora kwongerwa mubinyobwa, HMB irashobora guhuzwa na poroteyine zitandukanye, nka proteine ??yibyibushye, intungamubiri za protein, intungamubiri za poroteyine, hamwe na poroteyine y’imboga, kandi birashobora no gukoreshwa na vitamine n’imyunyu ngugu kugirango byongere imikorere y’ibicuruzwa. Amata y’amazi hamwe nifu y amata hamwe na HMB birashobora gukoreshwa kubantu bageze mu za bukuru ndetse n’abasaza kugira ngo bifashe kwirinda kwangirika kwimitsi, kandi birashobora no gukoreshwa muri siporo no kwinezeza abantu kugirango batange imirire yubuzima bwimitsi. Byongeye kandi, yogurt imwe ikora kumasoko, wongeyeho HMB irashobora kuzamura igitekerezo cyibicuruzwa byumwimerere kandi igatanga igitekerezo cyo kugabanya ibinure no gushiraho imiterere, kandi kongeramo ibikoresho fatizo bikora kuri ice cream nabyo ni uburyo bushya bwabashinzwe gukora ice cream benshi mumahanga. Ongeramo ibikoresho bya HMB birashobora gushimangira imikorere ya ice cream hashingiwe ku kwemeza uburyohe nuburyohe. Byongeye kandi, HMB irashobora kandi gukoreshwa mu tubari tw’imirire na bombo, nkibicuruzwa bizwi cyane by’imirire y’imirire ni Maximuscle, yongeramo garama 20 za poroteyine, garama 3.4 za vitamine monohydrate na garama 1,6 za HMB, byamamazwa kugira ngo bigabanye poroteyine, byubaka imitsi mu gihe biteza imbere gukira imyitozo. Abashinzwe ibiryo kugirango bagabanye ibinure bamaze igihe kinini bakoresha HMB kuri bombo, nka sosiyete y'Abayapani ISDG yakozeHMBbombo, ni bombo kubantu bubaka imitsi bakabura amavuta.

Nuburyo bwiza bwo gufata neza imirire mugukumira no kuvura syndrome de musculée,HMBbyemejwe n’ubushakashatsi butari buke bw’ubuvuzi, kandi HMB yerekanwe mubuvuzi yihutisha gukira ibikomere no kubuza gutwika. Kugeza ubu, iterambere no gushyira mu bikorwa HMB mu rwego rw’ibiribwa byo mu gihugu byatangiye, ariko hamwe n’ikurwaho ry’inzitizi zishingiye ku mategeko mu gihugu, ndetse no kuzamuka no kuzamura ibiribwa bitandukanye bikora HMB ku isoko ry’isi, byizerwa ko mu gihe cya vuba, HMB izaba ifite amahirwe menshi y’iterambere mu bijyanye no gukoresha ibiribwa.