Sucralose ntabwo yitabira metabolism mumubiri wumuntu kandi ntabwo yakirwa numubiri wumuntu. Hamwe na zeru zifite agaciro ka zeru, sucralose nigitekerezo cyiza gisimbuye abarwayi ba diyabete. Yagenzuwe kandi yemejwe na FDA mu 1998. Irashobora gukoreshwa nk'ibiryoha ku isi hose ku biribwa byose, kandi ntibigira ingaruka ku kuba glucose iri mu maraso. Irashobora kwakirwa nabarwayi barwaye diyabete. Byongeye kandi, sucralose ntabwo ikoreshwa na bagiteri yinyo y amenyo kandi irashobora kugabanya aside irike ikorwa na bagiteri yo mu kanwa hamwe no gufatira ingirabuzimafatizo za streptococcale hejuru y amenyo, bigira uruhare runini rwo kurwanya karies. Ubushakashatsi bw’inyamaswa bwerekanye ko sucralose ifite umutekano mukumara igihe kirekire kuri dosiye inshuro ijana kurenza urwego rwimikoreshereze yabantu. Ubushakashatsi bwigihe kirekire bwakozwe kubakorerabushake basanzwe bwabantu bwerekanye ko sucralose idafite ingaruka zidasubirwaho kubuzima bwabantu. Nyuma yigihe kirekire cyo gupima ibyemezo byumutekano, FDA yo muri Amerika yemeje ko ari inyongera ya GRAS (umutekano).

Sucralose yakoreshejwe cyane mu bwoko burenga 400 bwibiribwa, harimo ibinyobwa bya karubone, ibinyobwa bya karubone, ibinyobwa bisindisha, imbuto n'imboga zafunzwe, ibiryo n'amasosi, jama, ibicuruzwa bitetse, ice cream, ibikomoka ku mata, ibinyampeke bya mu gitondo, n'ibisosa bya buri munsi. Ibinyobwa bya calorie nkeya nisoko rinini ryogukora ibihimbano, hamwe nabaguzi miliyoni 87 muri Amerika bonyine. Coca Cola na PepsiCo bakurikiranye batangije ibinyobwa bya calorie nkeya bakoresheje sucralose nk'ibiryoha, bizibandwaho mu kuzamura isoko ry'ejo hazaza. Nta gushidikanya ko bizongera cyane icyifuzo cya sucralose ku isoko.