Nko mu ntangiriro ya 1930, abahanga mu bya siyansi bavumbuye ko guhura n’izuba cyangwa kunywa amavuta ya elayo, amavuta ya flaxseed, n’ibindi biribwa bikoresha UV bishobora kurwanya osteoporose. Ubushakashatsi bwakozwe n’abahanga bwerekanye kandi bwita vitamine D nk'ingirakamaro mu mubiri w'umuntu mu kurwanya osteoporose.

Vitamine D (VD mu magambo ahinnye) ni vitamine ikuramo ibinure, ikaba ari itsinda ryibikomoka kuri steroid bifite ingaruka zo kurwanya rike hamwe nuburyo busa. Icy'ingenzi ni vitamine D3 (cholecalciferol, cholecalciferol) na vitamine D2 (calciferiol). Vitamine D mu ndyo ahanini ituruka ku biribwa bishingiye ku nyamaswa nk'umwijima w'amafi, umuhondo w'igi, amavuta, n'ibindi. Ihindurwamo 1,25-dihydroxyvitamine D3 n'umwijima, impyiko, na hydroxylase ya mitochondrial hydroxylase, ifite ibikorwa byibinyabuzima kandi ishobora gutera synthesis ya calcium ihuza protein (CaBP) mumitsi yo munda, igatera kwinjiza calcium, kandi igatera kubara amagufwa. 7-dehydrocholesterol, ikomoka kuri cholesterol ikomoka mu mubiri w'umuntu, ibikwa mu buryo butagaragara kandi irashobora guhinduka cholecalciferol munsi y'izuba cyangwa imirasire ya ultraviolet. Ni vitamine D ya endogenous itera kwinjiza calcium na fosifore.

VD ikomoka kuri steroid. Ni kirisiti yera, ibora ibinure, ifite imiterere ihamye, irwanya ubushyuhe bwinshi, antioxydeant, idashobora kurwanya aside na alkali, kandi irashobora gusenywa no kwangirika kwa aside. Umwijima w'inyamaswa, amavuta y'umwijima w'amafi, n'umuhondo w'igi bikungahaye cyane. Ibisabwa buri munsi kubana, abana, ingimbi, abagore batwite, nababyeyi bonsa ni 400 IU (amahuriro mpuzamahanga). Iyo babuze, abantu bakuru bakunze kurwara osteomalacia, kandi abana bakunda kurwara. Niba calcium yamaraso igabanutse, hashobora kubaho gukubita amaboko namaguru, guhungabana, nibindi, nabyo bifitanye isano no gukura amenyo. Kunywa cyane vitamine D birashobora gutera calcium nyinshi mu maraso, kubura ubushake bwo kurya, kuruka, impiswi, ndetse no kwangirika kwa ectopique ya tissue yoroheje.