???? ?????????: ???? ???????? ?????? ?????: ?????? ?????????? ?? ????????? ??????? ??? ?????
1.1 ????? ?????? ???????? ?????? "0 ???? " ??????? ???? ???????
??? ????? ????????? ?? GB 28050-2011 ? ????, 100g/ml ? ≤0.5g ???? ?????????? ????? ???? "???? ????" ??? ????????? ???.
FDA ?????????: "???? ????" ????? ?????? ?? ???? ????? ????? ??? ?????? ???? ??.
??????? ?????? ????? ????????: "?????? ????? ??" ?? ?????? ?????? ???????? ???? ?????? ?? ?????.
1.2 ?????????? ?? ??????? ???????
????????? (C12H19Cl3O8) ??????????????? ?????? ???????? ???, ??? ???? ??????? ???? ????? ?????? ?????, ??:
??? ?????????? ????? ????? ????? (??? ???????? ???? ????)
???? ????????? ?????? ???????
?????????? ???????? (GI) 0 ??
???? ?????????: ???????? ??????????? ???????? ?????: ??????????? ??? ???????? ????? ????? ?????????
2.1 ????? ??????????? ????? ???
?????? ????????? ????? ?????? ???? ??????? ????????? ???? ?????????? ?? ??????? (1976):
????? ??? ??????????? ??????: ??????????????? ????? ???????? ????????? (SO2Cl2) ??? ???? ???? ???? ?????.
?????????? ???????? ?????: ???????/?? ???????? ???? ??????????? 99.9% ? ????????????? ??? ??????.
??????? ??????? ?????: 2024 ?? ??? ???? ????? ??????? ??????? 237?? ????? ?????? ??.
2.2 ??? ???????????? ????????? ?????
?????? ??????????? ?????? ???????? ??? ?? "???????-??????? ??????? ??????":
????? ????????? ?????????? ??? ????? ????????? ?????
??????????? ???????????? 40% ???? ???? ?? ??.
?????????? ???? ???? ????? ????? ????? 65% ???? ??? ?? ??.
(?????????? ??????? ???? ?????? ?????: ????????????? ??????????? ?????? ?????? ???? ???????? ???????? ???????????)
?????? ?????????: ?????? ????? ????????: ????? ??? ?? ??????? ?? ?????? ????? ???????
3.1 ?-???????? ???????? ???? ????????? ????????
2024 ?? ????????? ????? ?????? ??????? ??? ?? "???? ????" ???????? 120 ???:
17% ?? ???? ?????? ??? ???????????? ?? ??????? ??????? ?????? ???? ???.
?????????? ?? ?????????? ????????? ????? ???? ??????? 8% ?? ??????.
3.2 ????????? ?????? ???????
??? ??????? ?? ??????? ???? ?????? ?? ??????????????? (N=5000) ??????????:
????????????????? 62% ?? ??????? ?????? "???? 0 = ????????????? ???? ????" ????.
?????????? ??????? ???? ???? ?? ???? ??? 38% ?? ????? ???????? ??? ??.
ADI ?????? ??????? ????? ?????? ????? 9% ?? ????.
????? ?????????: ?????? ???????????? ????? ????????: ??????? ????? ??????
4.1 ?????????? ????????? ?? ??????????
?????? ?????????? ????? ?????????? ???? ?? ?????? 2024 ?????????? ???? ????? ???:
ADI ???? ???????? ??? ???? ?????? ??? ????? ?????? ????? β ????????? ????? ?? ?????.
???? ?????, ??????????? ?????????? ??? ?????? ???? ???????????? ???????? (p > 0.05)
4.2 ?????? ???????????? ?????
????? ??????? ?????? ???????? ????? ?????? ???? ??????????????? ???????? ???????? ?? ????? ???? ??????? ????:
????????? ?????? ????? ???? ????? 10 ?? (??????? 1) ??? ?????? ???????? ???? ?????.
????? ?? ?????? ????????? ???? ???????? ?????? ???????? ????? ????? ??? ?????.
??? ??????????? ???? ?? ??????? ????????? ???????? ?????? ?????? ???? ?? ?????.
????? ????????? ????? ????????: ?????? ????????? ???????? ?????
5.1 ??? ???????? ???????? ????? ???
??????????? ????? ????????? ?????? ?????????? ????????? "?????? ????????? ????????" ????????? ????.
?????????? ??? ??? 1.8 ???????? ??? ??? ?? ?? (2023 ?? 15 ??????).
5.2 ????? ??????????? ????????
????? ?????? ??????? ?????? ???? ?????????? ?????????? ?????? ?????? ??????? ????? ??????? ????.
????? ????? ?????? ?????? "???? ???? ?????? ???? ?? ?????????" ??????? ?????? ????.