??????????????????????? ?????, ?????????, ????????????? ?? ?????? ????? ??????? ??? ????????????????? ?? ??? ?? ??????? ?????? ????????? ????, ??? ????????????, ????????????? ????????? ???????????? ???? ????? ?????? ???????? ??? ???? ?????? ????????? ???? ?????? ????. ?????????? ????? ????? ???????? ?? ????????? ??????? ???? ?? ???? ????, ?????? ?????? ??????????????? ???? ?????? ?? ???? ???? ???????????? ?????? ?? ??. ??????????? ????? ?????? ??? ???? ???? ????? ??? ?? ???? ??? ????????????????? ATPase ?? ??? ??? Na+/K+ ATPase ?? ??????????????? ??? ?????? ??? ?? ???? ??? ?????? ????? ????? ???? ????. ???? ?????, ?????? ???????? ??? ?? ??????? ????? ??????????? ???????????? ??????? ?? ??? ??????????? ??????, ????????? ?????????????????, ?????? ???????, ?????????????? ???????????, ???????? ?????????? ?????? ?? ?????-????? ???? ???????? ?????? ??.

???????????S-adenosine-L-methionine ???????? ???????? ??? ???? ?????? ?? ?????, ????? ??????? ???????? ???????????? ??????????? ?? ??????? ?????????? ?????? ???? ?? ?????, ???? ???? ????????? ?????? ?? ?????????? ?? ???? ?????? ?? ?????, ?? ??????????? ??????????? ??? ?????????? ?? ?????.

?????? ???????? ????????????????????????? (CCT) ??? ????????? ??????????? ????? ???? ????????? ???????? ???????? ????? ??? ?? ???? ??? ??????? ?? ???????????? A2(PLA2) ??????????????? ???????, ??????? ???????????? ??????? ??? ????? ???? TNF-a/IL-1b ??????? ???????? PLA2 ??????? ????? ???????, ?????? ???????????? ????????? ???? ?? ?????? ??? ??????????? ????.

??????????? ??? Bcl-2 ???? ??????-??????????? ?????? ????????? ???? ?? ???? ??? ??????????????? ?? ??? ????? ???? ????????? ???? ????? ???????.

??????????? ?????? ??? ??? ?????? ?? ????????????????? ??? ??????? ??????????? ????? ?????????? ????, ??? ?? ?? ?? ??? ??????????? ??????????????? ?????? ???, ?? ?????? ??? ???? ???? ????? ??? ????, ?????? ??? ???? ???????? ???? ?????????? ???????? ?? ?????? ??????? ????????? ??? ????.

??????????? ????? ????????????? ?? ???????? ????????????????? ?????? ???? ?? ???? ??? ????? ??????, ?????????????? ?? ??????????? ?????? ???? ????? ???????? ?? ?????.

?????????? ??????? ???? ?????? ????? ??????? ??, ??????? ?????? ????? ????? ??.

???? ???? ???????????? ??????. ??? ??????? ??? ???????? ?????????? ?? ??????? ???????? ???? ????? ???????? ???????.

???? ?????? ??????? ???????????. ??? ??????? ???? ????? ????, ???? ?????????? ???????? ??????????? ???? ?????? ????? ???, ????? ??????? ?????? ?????, ??? ????????????? ???????? ???????, ???? ????? ????????, ???? ??????? ?? ????? ????? ????? ?.

??? ????????? ???? ????? ?????? ?? ?? ??????? ???????? ?????? ?????? ????? ???? ??????? ???????? ???????? ? ??. ?????? ??? ???????????? ?????? ?? ??? ??????? ????????? ???? ?????? ??? ???. ??????????? ??? ???, ???????? ??????? ??? ?? ??? ??????? ??? ???. ??????? ????????? ????? ????????? ??? ?? ?????????? ??????? ???????? ??????????? ????? ????? ????? ?????: ??????? ???????? ??????????? ?? ????????? ?? ???????? ?????? ???????????.

??????? ??? ???, ?? ??????? ??????? ??, ????????? ?? ??????? ?? ?????? ?? ????????? ??? ?? ????????? ??, ??????? ????? ??, ?????-????? ????? ???? ??, ?????? ?????? ???????? ?????????? ??? ???? ??????? ??, ????? ???????????? ???????????? 80% ?? ?????? ?????????? ?????????? ????? ??????.

?? ?????, ?????? ?????? ?????????? ?????????? ????????????? ??? ????????? ?? ??? ?????? ?? ????????? ??????? ??? ????????? ??. ???????????? ?? ???????????? ?????, ??? ????????? 90% ?? ???? ??? ????? ????? ??? ??? ??????????? ??? ???? ??? 1% ?? ??? ??? ?????????? ????? ????. ?????????? ???????? ?????? ?????? 2 ?? ??, ?????? ?????? ??? 1 ?? ?? ??? 24 ?? ????.

????? ????? ????, ?????? ?????? ??? 10 ?? ??? ????? ?????????? ????? ??? ?? ?????????? ?????? ????????? ???? ?? ??? ????? ???? ?? ??? ???????? ?????? ??? ???? ???? ???. ??? ???????????? ??? 48 ?? ???? ????? ???, ??? ????? ????? ??? ???????? ?? ???, ???????, ???? ?? ?????? ???? ?????? ???? ?????????? ????? ????? ????. ?????????? ?????? ?????? ???????? ?????? ??? ??? ??? ?? ???????????????? ??????? ??????????? ????? ?????????? ?? ?????, ??? ???????? ?? ??? ??????????? ??????????????? ?????? ?? ???? ???, ??????????? ?? ???? ???????.