????????????: ???? ???? ??? ?????? ????? ????????
????? ???? ???? ??? ??????? ????? ?????? 120 ??????? ????? ??????? ??? ???, ??? ???????? "??????? ??????" ??? ????????????, 25% ? ???????? ??????? ??????? ????? ?????? ??? ???? ?????????? ??????? ???? ???? ??????? ????. ???????? ??????? ?????? ???? ?????????? ????????????? ??? ???????? ??????????? ?? ???? ???? ???? ????????????? ???????? ??? ????? ?????, ???????????? "?????? ?????, ????????? ??????? ?? ???????? ???" ?? ????? ???? ???? ???? ??? ??????????? ????? ????? ??? ???? ??. ???? ?????, ??????????? ??????? ??? ????????? ??????? ?????? ?? ??????? ??? ??? ???, ??? ?????? ??????? ??????????? ?? ?????????? ?????? ?????????? ? ????? ????.
1, ???????? ????: ???????????? ???? ???? ??? ?????? "?????" ??? ???? ????? ????
1.1 ?? ???????? ???? ??????
???????????? (C ? H ?? O ?) ?? ???? ??????? ??? ???? ?? ??? ????????????? ?? ?????? ?? ????? ????:
???? ?? ?????????: ???? ?? ????????? ????? 70% ?? ?? ???, ?? ?????? ?? ??????? "????? ??? ?????" ?????? ????? ????;
?????? ???? ?????? ?????: ???????? ?? ??? ?????? ????? ???????? ????? ????? ??? ???, ???????? ??? ?????? ???????? ??????? ??? ???????? ??? ?????? ??;
???????? ???: ??? ????? ?? ????? ????? ?????? ???, ?????????? ?? ??????????? ???? ????? ???????? ?? ??? ?????? ???.
???????? ???????:
????? ???????: ?????????? ???????????? (???? ?? ?????) ?? ????????? ????? (??? ??? ????? ?????) ??? "??? ???????????" ?????;
???????? ?????????????: ?????? ??????? ???????????? ??????????? ?? ???????? ?????? ?????? ???? ???? ????????? ??????? ?????? ?????;
???? ?? ???????: AI ?????????? ????????? ?? ?????? ???? ?????? ?????? ????????? ?? ???????????? ??????? ??????? ????????? ???????? ???? ????.
1.2 ??????? ?? ??????? ??? ???????
??? ???????????? ???????? ??????? ???????????? "????????????? ?????" ????? ?? ??:
??????? ??? ???: 2023 ?? ???, ???????????? ?? ????? ???????? ??????? ???? 350000 ????? ??? ??? ??? ???, ???? ?????????? 80% ?? ??? ???? ?????????? ?????? ?? ???. Sanyuan Biotechnology ?? Baolingbao ???? ?????????? ???????? ????????? ???? ??;
??????? ?????: ????? ?????? ??????????? 2010 ?? ????? 12000 ??? 2024 ?? ????? 5800 ????? ???? ??????? ??? ????;
??????????? ??????????: ?????? ?????????? ??????????????? ????? ?????? ????????????? ????, ?????? ??? ?? ????? ??? ????.
???? ?????????: ???? ???? ??????? ???? ???? ????? 500 ??????? ???????????? ???? ?????? ??????? 2018 ?? ?????? 0.12 ??? 2024 ?? ?????? 0.07 ????? ??? ?? ??? ??? ?????? ????? ?????????? ?? ??? ??????? 65% ???????.
2、 ?????????? ??????: ???????????? ??? ???? ?????????? ?????????????? ??? ?????
2.1 ??????? ????????: ?????? ???? ??? ???????? ????? ??????? ??? ?????
???????? ??? ????: ???????? ???????? "????????????+??????? ??????????" ??????? ??????????? ????????? ???? ???? ????? ??? ?????? ??????? ?? ???? ?? ?????? ??????;
?? ??????: ??????? ???? ?? ?? ?? ????????? ????? ??? ???????? ??? ????? ???? ???????????? ?? ??????? ???????? ??? ?????? ?? "???? ???? ???? ???????" ?? ????;
??????????? ??????: ????????? ????? ???? ?????? ????? ?????? ????????? ????? ?? ??? ???, ?? ????? ??????????? ?????? ????? ???? ???????????? ?? ?????????? ???????? ?? ?????? ????;
???? ???????? ??????????: ???????????? "???? ???? ?????" ???????????? ?? ????????????? ?? ??????? ???? ??? ?? ??????????????? ??? ????????????? ??? ???.
?????? ????: 2023 ??, ????? ???????????? ??????????? 68% ?? ??? ????????? ?????? ???? ??? ?? ???, ?????????? 45% ?? ???? ???? ??????? ??? ??????.
2.2 ?????????? ???????????? ??????????? ??????
???? ????: 2023 ?? ??? ?????????? ?? ?????? "????????????+??????????" ???????? ?????????? ?????, ????? ???????? ???????? ?????? ???? ???????? ??????? 40% ????? ???? ?????;
?????? ????: ???? ???? ?????? ??????? ???????? ???? ??? ????????? ??????? ??? ???????????? ??????????? ???????? ????? ???? ????? ???????? ??? ????????? ?????? ?????;
?????????: ??????? ?? ???? ?? ?????????? ????????? ?? ?????? ????? ?????? ????? ???? ??????? ???? ???? ?? ?? ??? ????????????? ???????? ?????? ???? ???? ?????.
?????????? ??????: ???????????? ??? ?????????????? ????? ???, ???????? ???? ?? ?????? ??????? ????????? ???? ????? ??????? ? ??.
3, ?????? ??????: ???????? ???? ??????????? ????????
3.1 ??? ?????? ??????? ???? ????????
2024 ?????? ???????, ???????? ??? ??? ??????? ?????????? ?????? ?????? ?????????? ????????? ??? ??? ?????:
???????????? ????????: ??? 5?? ???? ?????? ??????????? 12000?? ????????? ?? ???, ????? ???????????? ??????? 15 ?????? ???????? ????????? ???? ??????? ???????? 1.3 ???????? ???? ???;
????????? ?????????: ???????????? ??????? ???? ????? ???? ?????? ?? ???? ?????, ??? ?????? in vitro ?????? ?????? ???? ?????? ?? ?????;
??????? ??????: ????? ???? ?????? ???? ?????? ??????, ??? ?????? ????? ????? ??????? ??? ??????? ???? ????????? ???????? ???? ????? ???? ????.
3.2 ?????? ???????? ??????? ????
??????? ???: ?????? ??????????? ????? ?????? ???? ????, ????? ????????? ?? ?????? ??????? (??????? ???? ??????????? ??? ?????);
???? ??????: 2024 ?? Nature Metabolism ?? ??? ?? ?????????? ????, ???? ????? ??? ?????????? bifidobacteria ????????? ?????? ?????, ??????? 50 ? ??? ????? ??????? ???? ?????? ???? ??????? ????? ????????.
3.3 ?????? ?????? ???? ????
EU EFSA: 2024 ?? ????? ?????? ????? (ADI) ???? ?? ??????? 1.2/kg ????? ??????? ??? ?? ???, "???????? ???????? ???? ???????? ???" ???? ??????? ????;
??? ????? ?????? ?????? ???????????? ?? ?????? ?????? ???? ?? ??????? ?????????? ????????? ????? ?? ??? ???, ?????? ?????????? ????????? ???? ??????;
???????? ????? ????: ??? ??? ???? ???????? ????? ?????? "???? ???? ??? ?????? ????????? ?????? ???? ??????????" ?????? ?? ??? ???, ?? ??? ??????? ???? ??? ???????? ??????? 7.5 ????????? ???? ?? ??????? ????.
4, ????? ??? ?????: ???????? ??????? ?? ??????????? ??????
4.1 ?????? ????????? ???????????? ?? ???????? ???????
???? ????? ?????: ?????????? ?????????? ????????? ?? ???? ?? 90% ????? ???? ??? ??? ???? ??? ?? ???????? ??? ????;
??????????? ??????? ?????: "?????????? ?????????" ???????? ????? ???? ??????? ?? ?? ???? ??? ??????? ?????;
???? ?????????: ????? ??? ??????? ??????? ?????? ??????, ???????????? Escherichia coli ????? ?????? ??????? ??? ??? ?????? ??????? ???????? 70% ???? ??? ??.
4.2 ?????? ?????? ?????? ??? ?????? ?????
?????????? ????: "????? ??? ?????? ?? ?????? ?? ?????? ?????????" ?????? ????? ???? GABA (???? ???????????????? ?????) ??? ???? ?? ??;
????????? ????? ???? ?????: pH ????????? ????? ???????????? ???????? ??? ??? ?????? ??????? ????????? ?????? ???? ??? ???? ?? ?????? ????;
????????? ?????????: ????? ?????? ???????????? ???? ???????????? ?? ?????? ?? ??????? ?????? ?????? ?? ?????????? ???????? ?????.
4.3 ???? ???? ???? ?????? ?? ?????
???? ?? ?????? ???????????: ?????? ????? ?????????? ???? ??? ????????? ??? ????? ???? ?? ???? ??? ???? ?????? ???????????? ???? ??? ???;
???????? ????? ?????????: ????????????? ???????????? ??????? (?????/??????) ???????? ????? ??????? ????? ????;
???????? ???????: ???????????? ????????? ???? ???? ??? ???? 8 ?? ???????? ??? ???, ?????? ????????? ?????? ?????? ???????????? ????????? ?? ??????.
??????: ?????????? ????? ?????? ??????
???? ???? ??? ?????? ????????????? ??? ??? ??????????????? ?????? ??????? ?? ???? ???? ?? ????? ???????????. ???????? ??? ???? ?? ???? ??????????? ??? ??? ??? ???, ?? ????????? ???? ???? ??????? ????? ???? ??? ?????? ??: ???????? "???????" ???????? ?????????? ??? ?????? ????, ??????? ?????, ?????????? ?????????? ?? ??????? ????? ??? ????????????? ???? ?????. ???? ??? ???? ?????? ??????? ????? ????? ??? ?????? ????? ????? ????? ?? ?????? ????????.