HMB ??? ?????? ?????????? ?????? ???? ???????? ?? ??????? ?????????? ??????????? ?? ??? ?????? ?????? HMB ???? ?????????? ??????? ?????. ???????? ???? ???? ??, ?????? ????? ????? 300 ??? 400 mg ????? ?????????? ?????? ???, ????? 90% ??? ???????? ????????????? ??????. ???? ???? ?????? ?????????? ??????, ???????????? ???? ?????? ??????, ?????? ??????????? ?? ??? ????? ????????????? ?????? ??? ??????, ?????? ??? ??? ?? ??? ?????? ??? ?????? ??? ?????? ????? ?????? ?????????? ??? ?????? ??????? ???? ?????? ??????, ?????? ????????? ?????? ?????? ?????? ?? ??? ????? ?? ?????? ???????? ???? ???? ???? ??? ?????????? HMB ?????? ?? ?????. ??? ???????, ???????? ???????? ??? ???? ???? ??? ??? ?????? ????? ??? ??????, ???? ???? ????? ??????????? ??????, ???? ???? ?????? ???? ?????? ?? ???? ???? ???? ?????? ??? ???? ??????, ?? ??????? ???? ?????????? ??? ?????????????? ??? ???? ??. ?? ?????, ????? ??? ????? ?????? ?????? ?? ??????? ?????? ?? HMB ??????? ????? ?? ??. ???????????? ?????? ?? ????? Ca HMB ????????? ????????? ?????? ?????? ?? ????????? ???????? ???????? ?????? ???? ????. Ca HMB ????????? ?? ????????? ??? ??????? ???????? ???????? ??? ?????????? ??????????? ???? ?????? ?? ???? ??? ?????? ?? ??????? ????? ???? ???????? ??????? ??????????? ??? ?? ?????.

2011 ??, ????? ????? ?????? ??????????? β-????????????-β-????????????????? ????????? (Ca HMB) ?? ?????? ??????? ??? ????? ?????, ??????? ???? ???? ??????, ????? ?????? ????? ?????? ????, ????????? ???????? ≤3 ???????/????? ?? ??????? ????. 2017 ??, ????? ?????? ?? ????? ??????? ?????? Ca HMB ?? ?????? ???? ??? ???? ?????? ???? ??? ??? ????? ?????? ??? ?? ??????? ?? ???, ??????? ??????? ?????? ???? ????? ???? ??????? ??????? ?????? ???? ??? ????. ??? ????, ???? ?? ???? ????????, ?????? ????????, ?????? ?? ?????? ????????, ??????, ???? ?? ????? ?? ????? ???? ???? ?????? ?????? Ca HMB ?????? ?????? ??? ?? ???, ????????? ???????? ????? ≤3 g/????? ?? ???, ?? ?????? ?????? ?????? ???????? ?????????? ???????? ?????? ???? ???. 1995 ?? ?????? ???? ???? ?? ??? ???????? ?????? Ca HMB GRAS ??? ??????? ???? ??? ?? ?????? ???? ???? ?? ????? ???? ?????? ?????? ??. ?????? ??? 20 ???, Ca HMB ?????? ???? ???????? ???? ????????, ?????? ????????, ??? ????, ????? ???? ?? ??????? ???? ???? ????? ?????? ?? ??. Ca HMB ??? ???? ???????? ????? ???? ?? ??? ???? ?????????????? ?? ??? ?? ???????? ????, ??????? ???? ????, ?? ??? ?? ?????? ????, ?????????? ???? ???? ???? ?????????? ???? ?? ?????. ?? ?????????, ???????, ?? ??? ???? ???? ???? ???????? ??????????? ?????????????? ???? ?????? ?? ?????. ???????????? ?? ????? ????, Ca HMB ???? ???? ???????? ????? ???????? ?????? ???????????????? ????.