????????????????? ????????? ????? ?????? ?? ???, ??????? ?????? ??????????????????? ????? ?? ???????? ?????? ?????? ???? ????? ?????? ???? ???? ????????? ????? ???? ?????? ?? ??? ??? ?????? ????????? ?? ???????? ??????? ??. ???????? ????? ????, ????????? ????, ????????, ????????? ??????? ?????? ??? ?? ????????? ?? ????? ??? ???? ??? ?????????? ? ???? ???????? ?????? ??????? ?? ??? ??. ????? ??????????? ??? ??????, ???? ????? ??????, ??? ?????? (???? ??? ???? ??????? ?????????), ???????????? ?? ????????

??????????? ??? ???????, ?????????, ????????????? ?? ?????? ????? ??????? ??? ?????????????????. ?? ?????? ?????? ?????? ?????????????????. ?? ?????? ???? ?????? ?????????? ???????? ??????? ??. ?? ?????? ??? ??? ???????? ???????????? ?????????? ????????? ??????????? ?? ??? ?????? ?????????? ????????????? ??? ?????????? ??????????? ??.

??????????? ??? ??????? ?????? ???? ?????? ?????? ?? ???? ?????? ?????? ??????? ?? ??? ?????? ??? ???????? ??? ?????? ?? ?????? ?????? ?????. ?????????, ?????? ????????? ????? ?????? ?? ?????? ?????? ???? ??? ????????? ?????? ????? ???????, ????????? ????????????, ?????? ??????? ??????????? ?? ??? ??? ?????????? ?????? ?? ???, ? ??? ??????????? ??? ??? ????????????? ???? ??.

??????????????-??????? ????? ?????? ??? ???, ??? ??????????? ???????????? ????? ?????? ??????? ?? ?????? ???????????? ???? ?????? ???? ??????? ??? ????. ??? ?????? ???? ?????? ????? ?????? ?????? ?????? ??????? ??? ??? ?????? ??????? ??? ?? ??? ?????? ??????????? ?????? ??????? ??? ??? ?????? ??????????? ?? ???????? ??? ?????? ?????? ??.

??? ????? ?????? ?? ??????, ??????????? ?????, ?????? ????????, ????? ???? ????? ?????, ????????? ????, ????????, ????????? ??????? ?????? ???, ????????? ?? ????? ??? ???? ????????? ???????? ????? ?????? ?? ???, ??? ???????????? ?? ??????? ??? ?????? ???????????? ?? ????????? ?? ??? ???, ?????????? ?????? ?? ????? ?? ?????? ?????? ??. ?????: ????? ??? ???????? ???? ????? ????? ?? ???? ????? ?? ???, ??? ??????????? ??? ??????? ?? ??????? ????? ????? ??? ??????? ????? ???? ???? ??, ??? ??????? ????? ??????? ???? ????? ?? ??? ?? ?????? ???? ????? 75% ??? 90% ????? ??. ???? ??????? ????? ???? ????? ???? ?????? 35%-40.9% ?? ?? ??? ?? ????? ???? ??????? ???? ??? ???, ?????? ???, ???? ???????????? ??? ????? ?? ??????????? ???? ????? ? ???????.

?????? ??????? ??????:

1. 2002 ??, ???????? ?????? ????????? ?? ????? ????????? ????? ??? ?????? ?????? ?????? ?????? ?????? ?????? ???? ??????????? ????????? ??? ??? ?? ???, ??? ?????????? ??? ??????????? ???? ?????? ??? 3 ?? ??? ???? ?????? ??????? ???? ??? ???? [1].

2. 2009 ??, ????? ???????? ????? ??????? ????? ??? ?????? 4191 ?????? ???? ??? ??????? ??????? ?????? ??????? ???? ??? ?? ???, ????????????? ???????? ??? ?????????? ???? ?? ??????? ????????? ???? ????????? ???? ???????? NIHSS ????? ?? BI ????? ???? ?????? ?? ????, ???? ????? ?????? ????????? ???? ????, ???????? ????? ???????? ??? ???????? ????????? ?? ?????. ??? ??????? ??????? (≧2000mg/?????) ?????????? ????? ????? ?????? ?? ???, ???? ????? ????? ??????? ?? ???? ????? ???? ??? [2].

3. ???????? ????? ???? ?????? ??? ?????, ????, ???????-????, ????????-????? ????? ????????? ????????????? ???? ????? ??????????? ??? ??????? ???????? ??????? ???? ???????? ????? ????? ????????? ????? ???? ??????? ?????? ???? [3].

4. ????? ?????, ????, ??????? ?????????? ????? ???????-???? ?????? ??????????? ??????????? ?? ????? ?????? ??? ??? ?? ???, ????????????? ???? ???? ???? ?????? ??????????? ?????? ???????-???? ?????? ?????????? ?????? ???? ??? ?????????? ?? ???? [4].