1976 ??, ?????????? ?????? ????????? ?? ??????????? ?????????????? ???????? ?????? ???????, ????? ???????? ???????? ??? ???? ????? ???? ???????? ?? ?????????? ???? ??? ???, ?? ?????? ?????????? ?????? ????? ????? ??? ????? ?????, ???? ?????????? ???? ?? ????? ???, ?????? ?? ??? ???? ?? ??? ?????? ??????? ?????? ???. 1980 ????????, ?????????? ??? ??????????? ?????????? ?? ?????? ?????? ?????? ????? ???? ?????? ??????? ???? ?? ???, ????????? ???????????? ???????? ??? ??? ??????? ???????? ?? ???, 1991 ??, ?????????? ?????? ??? ??????? ???? ???? ??? ?????? ????? ???? ????? ??? ???. ?????? ???? ???? ?? ??? ???????? (FDA) ???? ?? ??? ???? ???? ???????? ????????? ??? ?????????? ????? ????, ???????? ???????? ?????????? ???, ?????????? ???????? ??????? ????????? ??? ?? ???, ?? ???????? ????? ??????? ?? ???, ?? ???? ?? ????? ?? ??? ?????? ????? ?????? ??. ??? ???????, ?????????? ?????? ???????? ???????? ?????? ?? ??, ???? ?-?????? ?????, ??? ?????????, ??????????? ???? ??????. ? ???, ????????????? ?????? ?? ????? ??? ??????? ???? ????????? ????, ?????????? ?????? ? ????????????? ??????? ??? ????? ?.

????????? ?????? ?? ?????????? ?? ???????

????????? ?????? ??????? ????????? ??? ??????????, ?????? ???? ??????, ???? ???? ?? ?? ???? ?? ????? ???? ???????? ???? ?? ???? ???????? ???? ??. ? ????, ????? ? ???? ????, ??? ???? ?????? ?????????? ???? ?????? ???? ?????? ??? ?? ???, ??? ??????????? ??? ??????? ??????? ???? ???, ?????????? ????????? (HCl) ?? ??????? ????? ???? ?????? ???????? ???? ????. ?? ?????, ????????? ??? ??? ???? ???? ??? ????????????? ?? ???? ???, ?? ??? ??? ?????????? ???? ?? ??? ?????? ??????? ??? ????.

2015 ??, ?? ????????? (?????????? ?? ??? ?????? ????? ?????) ?? ??? ????-???? ????? ?????????? ??????? ?? ?????????? ?? ??? ?????? ????? ????? ?????? ????? ???? TG-DSC-FTIR ??????? ?????? ?? ???, ????????????? ???? ???? ?????????? 120℃ ?? ??????? ???? ???? ??? HCl, H2O ?? CO2 ?????? ????. ?????? ?????????? ????????? ??? ???? ??????, ?????????? ??????? ???? ???? ???. ??? ?????????? ?????? ?????????? ????????? ???? ?????? ??????? ?????? ?? ???????????????? ????? ??? ???? ????? ???, ?????????? 200℃ ? ??? ??? ??????? ?????? ??????? ???? ?????? ?????? ?????? ???????? ????????? ???? ?? ?????? ?????. ????? ??? ??????? ??? ?????? ??????? ???? (> 200 ° C), ????????????? ???? ????? ?? ???? ??? ?-?????? ??????? ????? ???? ???????????????? ??. 2019 ??, ????? ???-???? (????????????? ?????? ????? ??? ?????????? ???? ???????? ????? ??? ???? ??????? ????. ?????????? ???? ??? ?? ?-?????? ??????? ???????? ???? ?????? ????? ????? ???? GC-MS ?????? ?? ???, ???????? ?????? ?????? ?? ???????????????? ????? ????? ???? ??? ???, ???????????????? ???????? ?????????? ????? ????? ??? ????? ??????? ??. ?? ?????, ??? ??. ?????? (????? ???????? ????????????? ?????? ??????? ??????????-?????????? ?? ????????) ?? ???? ??. 1H NMR ????????????, ??? ??????? ???????? ?? ???? ??????? ???????? ???? ?? ??? ?????? ???????????? ?? ???? ??????? ?????? ??????? ??? ??????? ??? ???. ?????????? ?????? ?????? ????????? ???????? ???? ?? ??? ?????????? ?? ??? ????????? ?? ??????? ?????? ??? ?????????? ??????????? ????.

2024 ??, ????????? ?????? ???????? ???????? ???? (????????????? ?????? ?? ?????????? ?? ??? ?????????? ??????? ?????? ?????????? ?? ???????? ?? ?????, ????????? ?????? ????? ??? ??? ???? ????? ?? ??? ???????????????? ????? ?????? ??, ???????? ?? ?????????? ?? ?????? ????? ??? ???????? ??? ???. ????????????? ???? ???? ??? ??????? ????, ?????????? ??? ??? ????????? ???? ???? ???? ??? ???? ??? ???????????????? ???? ??????? ??? ??? ?????. ????????? ?????? ?? ?????????? ??? ????? ??????? ??????.

????????? ???, ?????????? ?????? ???????? ?????? ?? ??? ?????? ??????? ????. ????????? ?????? ???????, ??? ???? ?????? ????? ???? ?????????? ?????? ????? ?????, ????????? ????????????? ????? ??? ?????? ?, ??? ???? ????? ?????? ??????? ????????? ?? ?????, ????? ??? ??? ??? ??? ?????? ???????? ????? ?????, ?????????? ?????? ??? ?????? ?????? ????? ???? ?????? ???? ????. ?? ?????, ????? ???? ????? ???? ????????? ?? ??? ???, ????? ???????????? ???????? ???? ????? ?? ????????? ?????????? ????? ????? ?????? ??.