1930 ?????? ???? ???????, ???????????? ?????? ???? ????? ???????? ?????? ?? ????? ????, ?? ??? ???? ?? ??????? UV ?????? ???? ???? ???????? ???????? ??????????????? ????? ?????? ???? ?? ???? ?? ???? ????? ???. ???????????? ?????? ??? ?? ??????? ??????? ????? ??????????????? ????? ?????? ???? ????? ???? ?????? ?????? ??????????? ???????????? ??? ??????? D ???????? ??? ??? ???.

??????? D (???????? VD) ??? ????? ????????? ??????? ??????? ?? ??? ?? ??????-????? ?????? ?? ???? ????????? ???? ?????????? ??????????? ???????. ?????? ?????? ??? ????? ??????? D3 (cholecalciferol, cholecalciferol) ?? ??????? D2 (calciferol) ?. ?????? ??? ??????? D ??????? ?????? ???? ??????, ?????? ?? ???, ???? ???? ???? ???? ????? ??????. ?????? ???????? ???, ?? ???? ??????????? ??? ??????? ??????? ?? ?????????????? ???????? ??????? ????????? ????. ?? ??????, ?????? ?? ????????????????? ???????????????? ????? 1,25-?????????????????????? D3 ??? ????????? ?? ??? ?? ??? ??????????? ????????????? ??? ??? ?????? ?????????? ????????? ????? ????????? (CaBP) ????????? ???????? ?? ?????, ????????? ??????? ?????????? ?? ?????, ?? ????? ?????????? ?????????? ?? ?????. ?????? ?????? ??????????? ?????????????? ?? 7-?????????????????????, ?????????????? ???? ?? ??? ??? ???? ???? ?? ????????? ???? ???? cholecalciferol ??? ????????? ?? ?????. ?? ????????? ?? ???????? ??????? ?????????? ??? ?????? ??????? D ??.

VD ??? ?????????? ?? ??????????????. ?? ???? ?????? ????????? ?? ???, ????? ????????? ?? ???, ?????? ???, ??? ??????? ??????????, ???????????????, ???? ?? ????? ??? ?????????? ???? ??? ??? ???? ???? ?????? ????? ??? ???. ???? ??????, ???? ????? ???? ?? ?????? ?? ??? ???????????? ??????? ?. ???????, ?????, ?? ?????? ???? ?????????, ?????? ????????? ?? ???? ??? ???????? ???? ????? ?????????? IU 400 (?????????? ???) ??. ????????? ????? ???, ??????????? ?????????????? ????? ?????? ?? ???, ?????? ?????? ????? ?????? ??. ??????? ????????? ??? ???????, ??? ?? ??? ?????, ???????? ???? ??? ??? ???? ???, ??? ??? ??????? ? ??????? ??. ??????? D ???? ??? ???? ???????? ????? ????????? ???? ???, ???? ????? ???????, ????, ????? ?? ???? ??? ?? ????? ????????? ??? ??? ??? ???.