Tea ndechimwe chezvinwiwa zvakakurumbira munyika, kunyanya muChina. Tea muChina haisi kunwa chete, asiwo chiratidzo chehupenyu mararamiro uye tsika.

Kunwa tii kunoonekwa semararamiro ane hutano nekuti tii ine akasiyana siyana anobatsira makomisheni, senge makatechini, tii polyphenols uye caffeine. Ongororo dzakawanda dzakaratidza kuti tii inobvisa inogona kurambidza kenza, kuwedzera hupenyu, kuderedza njodzi yeBP, chirwere cheshuga, chirwere chemoyo uye zvichingodaro.

Kwete-doro fatty chiropa chirwere (NAFLD) ndiyo inowanzozivikanwa yechirwere chisingaperi chechiropa muChina, ine vanopfuura mamiriyoni e150 varwere. Parizvino, hapana mishonga inobvumirwa kurapa chirwere chisingaiti chiropa chechiropa, uye varwere vanogona kungopindira nekuchinja kwekudya uye kurovedza muviri. Nokudaro, pane chido chekukurumidzira kugadzira nzira itsva dzekurapa.

Munguva ichangopfuura, Vatsvakurudzi vanobva kuChina Medical University vakabudisa bepa rine musoro unoti "Epigallocatechin gallate inoderedza chirwere chisingaiti chiropa chechiropa" mumagazini yeClinical Nutrition kuburikidza nekudziviswa kwekutaura uye basa reDipeptide kinase 4 ".

Ichi chidzidzo chakasimbiswa kuburikidza nekliniki randomized controlled trials, mhuka yekuedza uye in vitro kuedza kuti EGCG, iyo huru bioactive ingredient mu green tea, inobatsira kuvandudza mafuta echiropa, ECGC inhibits lipid accumulation, inhibits kuzvimba, inodzora lipid metabolism, inodzivirira kukuvadzwa kwechiropa, uye inovandudza isiri-doro fatty chiropa ne inhibiting yekutaura kwepedyl 4. (DPP4).

Dipeptide kinase 4 (DPP4), protease inoparadzanisa huwandu hwema substrates pamusoro pesero, yave ichiunganidza uchapupu hwokuti DPP4 inobata basa mukuvandudzwa kweNAFLD, nevarwere veNAFLD vachiratidzira plasma yakakwirira yeDPP4 basa kana ichienzaniswa nevanhu vane hutano.

Muchidzidzo ichi, vatsvakurudzi vakaongorora kukwanisa kushanda kweEGCG kune varwere vane NAFLD kuburikidza nekliniki randomized controlled trials, vakacherechedza kuvandudzwa kweEGCG pachiropa chemuenzaniso wembeva kuburikidza nekuedza kwemuenzaniso wemhuka, uye vakaongorora nzira yeEGCG kuvandudzwa muNAFLD kuburikidza ne in vitro experiments.

Muchiedzo chekliniki chakarongeka chinosanganisira vatori vechikamu 15 neNAFLD, EGCG yakadyiwa nemapiritsi eti polyphenol, uye data yechiropa yakayerwa pakutanga, vhiki dze12, uye mavhiki makumi maviri nemana.

Zvigumisiro zvakawana kuti varwere vaiva nehuwandu hwemafuta echiropa mushure memavhiki makumi maviri nemana eEGCG kurapwa zvichienzaniswa nekutanga, uye vaviri vevarwere vaiva nemafuta echiropa kuregererwa mushure mekupera kwevhiki ye24 yekurapa. Pamusoro pezvo, kutenderera kwechiuno kwevarwere uye huwandu hwecholesterol hwakadzikirawo zvakanyanya mushure memavhiki makumi maviri nemana.

Kuongorora kwakaratidza kuti mushure memavhiki e24 eEGCG kurapwa, AST mazinga akaderedzwa uye mazinga eDPP4 akaderedzwawo.

Renal function analysis yakaratidza kuti serum creatinine mazinga uye glomerular filtration rate yakaramba iri mukati mehutano hwemazuva ose, zvichiratidza kuti EGCG ine kuchengetedzwa kwakanaka.