(1) Curiyayaasha nolosha ee dabiiciga ah

Sida monosaccharate dabiiciga ah, mannose waxaa laga helay epidermis ee tufaaxa (0.7-1.2%) iyo liin (0.3-0.8%). Qaabka unugyadu waxa uu ahaa ?. C?H??O? iyo gulukoos?. 8. Inta lagu jiro dheef-shiid kiimikaad ee bini'aadamka, mannose wuxuu galaa unugyada iyada oo loo marayo gaadiid-qaade gaar ah, GLUT1, laakiin ma dhaqaajiyo nidaamka qarsoodiga insulin-ta, hanti ka dhigaysa doorasho macaan oo badbaado leh dadka qaba sonkorowga 78.

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(2) Kor u kaca cuntooyinka cusub ee lagu daro

2023, Komishanka Caafimaadka Qaranka ayaa konjac mannose oligomeric ku taxay cunno cusub oo ceeriin ah, taasoo calaamad u ah gelitaanka rasmiga ah ee mannose ee goobta codsiga warshadaha cuntada 7. Heerka polymerization ee mannose oligosaccharides ee laga helay enzymatic hydrolysis of konjac glucomannan waxaa lagu xakameynayaa 2-10 unug sonkor ah, taas oo aan haysan oo kaliya guryaha dabiiciga ah, laakiin sidoo kale waxay leedahay la qabsiga habraaca. 7 ayaa lagu dabaqay in ka badan 20 nooc oo cunto ah sida cabitaano aan sonkor lahayn iyo buskud shaqaynaysa.

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Marka labaad, habka awood-siinta caafimaadka leh ee mannose

(a) Caqabadda dabiiciga ah ee nidaamka kaadi mareenka

Xogta caafimaadku waxay muujinaysaa in 2g oo mannose ah maalintii ay yarayn karto dhacdooyinka caabuqa kaadi mareenka ee soo noqnoqda ee haweenka 38%?8. Nidaamkeeda wax-qabad waxaa ka mid ah:

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Nadiifinta jirka: 90% qaadashada waxaa laga soo saaraa kaadi mareenka 30-60 daqiiqo gudahood, bakteeriyada pathogenic (sida E. coli) ayaa laga soo saaraa jirka 8;

? biofilm dildilaaca: burburin β-1, 4-glucoside bond ee bakteeriyada biofilm, hagaajin waxtarka bakteeriyada ee antibiyootiga 3 jeer ?78;

Nidaaminta difaaca jirka: waxay kor u qaadaan dheecaanka difaaca ee unugyada epithelial-ka kaadi mareenka, kor u qaadaan difaaca deegaanka 8.

(2) Ilaaliyaha aan la arki karin ee caafimaadka mindhicirka

Konjac mannooligosaccharides waxa ay badin kartaa probiotics sida bifidobacteria, waxa ayna kordhin kartaa tirada badan ee dhirta xiidmaha 25%?7. Tijaabo caafimaad oo lagu sameeyay Isbitaalka Kulliyada Caafimaadka ee Wuhan Union, ka dib qaadashada mannose oligosigro muddo 4 toddobaad ah, inta jeer ee saxarada saxarada ayaa kor u kacday 2.3 ilaa 4.1 jeer usbuucii, iyo dhacdooyinka kala-baxa caloosha ayaa hoos u dhacay 62%?7.

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(3) Qalab loogu talagalay ka-hortagga iyo xakamaynta cudurrada dheef-shiid kiimikaadka

Si ka duwan macaaneeyaha macmalka ah, mannose wuxuu leeyahay tusaha glycemic (GI) ee 0, iyo beddelidda sukrose ee alaabta la dubay waxay hoos u dhigtay heerka ugu sarreeya ee sonkorta dhiigga ka dib 2.1mmol/L ee bukaanka sonkorowga ?78. A 2024 Joornaalka Nafaqada Daraasada ayaa xaqiijisay in mannose uu hagaajiyo dulqaadka gulukooska daciifka ah ee bukaanka u adkeysiga insulin ?7 iyadoo la dhaqaajinayo dariiqa AMPK.

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3.Habab cusub oo ku saabsan warshadaha cuntada

(1) Tusaalooyinka horumarinta cuntada ee shaqaynaysa

Cabbitaannada ilaalinta kaadida: 500mg/ dhalo mannose oligosaccharides ayaa lagu daray cabitaan kakan oo karamberriga ah oo nooc gaar ah leh, mugga iibkuna wuxuu dhaafey 2 milyan oo kiis qeybtii hore ee sanadka 7;

Roodhida sonkorta lagu xakameeyo: rootiga beddelka cuntada ee lagu sameeyay konjac iyo mannose-oligosaccharide waxay leedahay 45% karbohaydrayt ka yar iyo saddex jeer ka badan fiber7;

Xoojinta nafaqada carruurta: Ulaha jiiska ee maansada lagu daray waxay kor u qaadi kartaa nuugista calcium 18%, kaas oo lagu daray 30% nidaamka sahayda cuntada ee xannaanada 7.

(2) Horumarrada farsamaynta hal-abuurka tignoolajiyada

Tiknoolajiyada la hago ee enzymatic hydrolysis ee ay sameeyeen shirkadaha Hubei waxay kordhisay heerka beddelka konjac glucomannan min 58% ilaa 92%, waxayna hoos u dhigtay qiimaha wax soo saarka 40%?7. Codsiga habka microencapsulation waxay kordhisay xasilloonida mannose ilaa 60 daqiiqo at 120 ℃, waxayna balaadhisay codsigeeda goobta dubista ?78.

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4.Aqoonsiga sayniska iyo codsiga macquulka ah

(1) Xeerka Dahabka ah ee xakamaynta qiyaasta

Xaddiga badbaadada: hal qaadasho kama badna 3g, qaadashada maalinlaha ah waxaa lagu xakameynayaa 5g gudahood, xad-dhaafka ah wuxuu keeni karaa calool xanuun, shuban (dhacdooyinka qiyaastii 7%)?8;

Digniin dadweyne oo gaar ah: Bukaannada ku filnaansho la'aanta kelyaha heerka soo saarista ayaa hoos u dhacay 50%, waxay u baahan yihiin inay isticmaalaan 8 iyadoo la raacayo hagidda dhakhtar;

Nidaamka isku-dhafka ah: Marka lagu daro soosaarkii karamberriga, saamaynta bakteeriyada ayaa kordhay 2.3 jeer 8.

(2) Horumarka warshadaha ee heerarka calaamadaynta

Xeerarka Guud ee Calaamadaynta Nafaqada ee Cuntooyinka La Diyaariyay sida wax laga beddelay 2024 waxay u baahan yihiin:

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Mannose waa in si gaar ah loogu calaamadiyaa liiska maaddooyinka oo aan lagu qasin ereyga guud "macaan" 7;

Sheegashada shaqadu waxay u baahan tahay in la calaamadiyo "ma aha daawaynta mukhaadaraadka kale"8;

Qiyaasta ≥1g/100g waa in la calaamadiyaa "waxa laga yaabaa inay keento raaxo la'aan yar oo xiidmaha" 7.

1.Khilaafyada iyo rajada mustaqbalka

(1) Diirada jirta ee muranka

Saamaynta muddada-dheer ee la arki karo

Dabiiciga ah: Haddii habka enzymatic hydrolysis beddelo sifooyinka lagama maarmaanka ah ee walxaha uu keeno dood tacliimeed 7;

Saamaynta silsiladda deegaanka: Balaadhinta beerashada Konjac waxay keentay isbeddelka 30% ee dhul-dalagga dhaqameed, taas oo saamayn karta kala duwanaanshaha noolaha 7.

(2) Jihada horumarinta tignoolajiyada

Codsiga saxda ah: Horumarinta mannose devatives gaar ah noocyada kala duwan 8;

Wax soo saarka cagaaran: Noocyada Konjac oo ay hagaajisay tignoolajiyada CRISPR, maadada glucomannan waxay ka korodhay 60% ilaa 85%?7;

La socodka caqliga leh: Aalad la xidhi karo waxa ay la socotaa fiirsiga mannose kaadi mareenka wakhtiga dhabta ah si loo helo dheeraadka shakhsi ahaaneed 8.

Gabagabo

Sida tusaale ahaan isdhexgalka dabeecadda iyo tignoolajiyada, mannose ma aha oo kaliya inuu sii wado xigmadda qadiimiga ah ee geedka tufaaxa, laakiin sidoo kale wuxuu iftiimiyaa iftiinka injineernimada cuntada casriga ah. Iyada oo la raacayo hagidda istaraatiijiyadda caafimaadka qabta ee Shiinaha 2030, wax-ka-qabsigan shaqaynaya iyo badbaadada leh ayaa dib u qaabaynaysa xudduudaha fahamka dadka ee cuntada lagu daro. Si kastaba ha ahaatee, waxaa lagama maarmaan ah in la ogaado in isticmaalka macquulka ah ee wax kasta oo lagu daro ay tahay in lagu saleeyo cunto dheellitiran, sida "Cunnada Lagu daro ee aan laga Maarmi karin" ayaa tiri: "Sayniska iyo tignoolajiyada ayaa ka dhigay cuntada suurtogalka ah, laakiin ixtiraamka dabeecadda ayaa had iyo jeer ahaa aasaaska warshadaha cuntada.