Dhinaca cilmi-baarista caafimaadka mindhicirka, Polydextrose ayaa muddo dheer lagu sifeeyay inay tahay fiber-cunto oo caadi ah oo biyaha ku milma. Si kastaba ha ahaatee, dhowr daraasadood oo horudhac ah ayaa sanadihii ugu dambeeyay muujiyay in unugyadan synthetic ee si aan kala sooc lahayn loogu sameeyay gulukoos ay tahay "ciyaaryahan badan" oo dib u qaabeeya microecology-ga mindhicirka iyada oo loo marayo habka saddex-geesoodka ah ee "sharciga viscosity-ka - quudinta saxda ah ee microbiota - falcelinta cascade metabolite". Daraasadii ugu dambeysay ee Dabeecadda Gastroenterology ee 2024 waxay muujineysaa in qaadashada maalinlaha ah ee 10-15g ee polyglucose ay kor u qaadi karto daacadnimada xannibaadda mindhicirka 37% waxayna hoos u dhigtaa heerka cuncunka caabuqa IL-6 29%. Daah-furkani kaliya ma beddelo garaadka dhaqanka laakiin waxa uu sidoo kale dhalinayaa mowjado codsi ah oo isdhaafsan oo u dhexeeya warshadaha cuntada ilaa dawooyinka kiliinikada.

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Qofkastaoplaceholder0 Cutubka 1 Go'aaminta Sayniska: "Garaadka Dheefshiidka oo dhan" ee molecule

Youdaoplaceholder0 1.1 Viscosity deformation: "Jawaabta caqliga leh" ee caloosha ilaa xiidanka

Kala-duwanaanta polydextrose waxay ku jirtaa isbeddelka viscosity-ka ka jawaabaya:

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Youdaoplaceholder0 Caloosha (pH 1.5-3.0): Silsiladda molecular waxay ku xiran yihiin bonds hydrogen si ay u sameeyaan qaab-dhismeedka shabakad saddex-cabbir ah, saabuunta viscosity ilaa 1500 mPa·s, waxay hoos u dhigtaa heerka faaruqinta caloosha ilaa 45% (marka la barbar dhigo kaliya 20% fiber)

Youdaoplaceholder0 Mindhicir yar yar (pH 6.0-7.4): Xidhiidhada hydrogen qayb ahaan waa jabay, viscosity waa la dhimay ilaa 400 mPa·s, iyo adsorption bile acid waxa ay yaraynaysaa nuugista kolestaroolka 18% iyada oo aan saamayn ku yeelan nuugista nafaqada;

Youdaoplaceholder0 Colon ? (pH 7.0-7.5): Halsano microbial waa la bilaabay, viscosity burburay oo ka hooseeya 50 mPa·s, acids dufan-gaaban (SCFAs) ayaa la sii daayay, iyadoo diirada butyric acid kordhay by 3.2 jeer, hagaajin toos ah u dhaqdhaqaaqa mindhicirka unugyada epitheliureal unugga.

Youdaoplaceholder0 Technology Breakthrough: Tiknoolajiyada DSM ee SmartVisc? waxay u habeyn kartaa qalooca viscosity qaybo kala duwan iyadoo nidaaminaysa heerka polymerization (qiimaha DP), sida qaacidada G-nooca si gaar ah loogu talagalay bukaanada qaba reflux gastroesophageal, kaas oo sameeya filim difaaca jirka oo leh viscosity ilaa 2000 m.

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Youdaoplaceholder0 1.2 Xeerka Microbiota: Laga bilaabo "quudinta spectrum ballaaran" ilaa "faa'iidada la beegsanayo" ?

Prebiotics-dhaqameedku waxay inta badan si aan kala sooc lahayn u kiciyaan dhammaan microbiota, halka polydextrose ay muujiso awoodaha sharciyeed ee saxda ah:

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Youdaoplaceholder0 Kahortagga korka: Gobolka viscosity-ga sare wuxuu ka dhigayaa xannibaad jireed xiidanka u dhow, xannibaya ku-dhejinta bakteeriyada pathogenic (sida Escherichia coli), hoos u dhigista heerka gumeysiga pathogenic 52%;

Youdaoplaceholder0 Kororka hoostiisa: jajabyada Oligosaccharides ayaa si gaar ah loo isticmaalay bakteeriyada faa'iido u leh sida Bifidobacterium iyo Roseella, iyo badnaantooda ayaa kordhay 68% ka dib 8 toddobaad oo faragelin ah (oo ku salaysan isku xigxiga metagenomic);

Youdaoplaceholder0 Isku-dhafka dheef-shiid kiimikaadka: Butyric acid waxay soo saartaa waxay kicisaa soo-dhoweeyaha GPR109A, waxay kicisaa kala-soocidda unugyada T ee nidaamsan, waxayna wanaajisaa tusaha dheelitirka difaaca mindhicirka ilaa 0.91 (xadka caafimaadka> 0.85).

Youdaoplaceholder0 Cutubka 2aad Codsiga Duufaanta: Dhaqanka Xudduudaha laga bilaabo miiska ilaa Sariirta Cusbitaalka

Youdaoplaceholder0 2.1 Warshadaha Cuntada: "Matoorka aan la arki karin" oo leh hawlo la cusboonaysiiyay

Youdaoplaceholder0 Kacaanka Dubista : Kooxda Meiji ee Japan ayaa soo saartay buskud eber ah iyaga oo ka faa'iidaysanaya awoodda haynta biyaha (8.3g biyaha / g) iyo xasiloonida kulaylka (dulqaadka 220 ° C) ee polyglucose, hoos u dhigista isbeddellada gulukooska dhiigga ee ka dib 41%.

Youdaoplaceholder0 Hal-abuurka Cabbitaannada: Biyaha mindhicirka ee Nongfu Spring, kaas oo adeegsada gaaska soo saara gaaska halsano ee gumeysiga ee polyglucose si uu u yareeyo calool-istaagga iyada oo aan xanaaqin, laga iibiyey in ka badan 8 milyan oo dhalo bishii ugu horreysay suuqa;

Youdaoplaceholder0 Horumarka Beddelka Cunnada: Soylent ee Mareykanka waxay isticmaashaa qaacido-mujis-jilicsan si ay u kordhiso tamarta si tartiib ah u sii deyneysa ilaa 6 saacadood oo ay u wanajiso dulqaadka orodyahannada marathon-ka 23%.

Youdaoplaceholder0 2.2 Nafaqada kiliinikada: "Gaashanka xannibaadda mindhicirka" ee bukaannada ICU

Daraasadda RCT ee Isbitaalka Sir Run Run Shaw, Dugsiga Caafimaadka, Jaamacadda Zhejiang (n=204) waxay tuseysaa in:

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Youdaoplaceholder0 Kahortagga caabuqa: Bukaannada ICU ee lagu kabo 15g oo polydextrose ah maalin kasta, dhacdooyinka sepsis-ka 'enterogenous sepsis' ayaa hoos u dhacay 44%;

Youdaoplaceholder0 Dayactirka xuubka xuubka: Plasma ligonin (calaamad u dhiganta dheecaanka mindhicirka) ayaa hoos u dhacay 31% iyo cufnaanta unugyada goblet ayaa kordhay 39%;

Youdaoplaceholder0 Immunomodulatory : U fiirsashada Serum IgA ayaa kordhay 28%, iyo saamiga unugyada CD4+/CD8+ T ayaa ku soo noqday heerka caadiga ah.

Qofkastaoplaceholder0 Cutubka 3 Kacaanka Farsamada: Laga Soo Bilaabo Naqshadaynta Molecular ilaa Nafaqada Saxda Ah Ee La Karfiyay

Youdaoplaceholder0 3.1 Wax ka beddelka qaabdhismeedka: Fur habeynta baahida

Youdaoplaceholder0 Viscosity Bartilmaameedka : Iyadoo la soo bandhigayo silsiladaha dhinaca sorbitol, polyglucose (nooca C) gaar ah oo xiidan ah ayaa la sameeyay, kaas oo maangalkiisu aad hoos ugu dhacay 10 mPa·s marka loo eego pH 7.0, gaar ahaan dadka calool istaaga;

Youdaoplaceholder0 Dhaqan la wanaajiyey: Roguet, France, waxay horumarisay tignoolajiyada Probiocoat? microcapsule taas oo koobaysa probiotics ee matrix polyglucose, kordhinaysa heerka badbaadada acid gastric min 15% ilaa 92%.

Youdaoplaceholder0 3.2 Sirdoon macmal ah: dildilaaca xeerka faragelinta gaarka ah

Nidaamka "Twin Digital ee mindhicirka" oo ay dhistay NutriAI, oo ah shirkad Israa'iil ah, waxay isku daraysaa 200,000 oo xaaladood oo ah xogta dhirta xiidmaha ee xiidmaha iyo moodooyinka dhaqdhaqaaqa dareeraha, kuwaas oo saadaalin kara jawaabta shakhsi ahaaneed ee polydextrose:

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Youdaoplaceholder0 Kordhinta qiyaasta : 8-12g/maalintii + fructooligosaccharides nidaamka isku darka ee lagu taliyay bukaannada IBS waxay hoos u dhigtay dhacdooyinka kala-baxa caloosha 67%;

Youdaoplaceholder0 Muuqaal ku haboon: Qaab jimicsi xoog leh oo loogu talagalay ciyaartoyda, kaas oo kordhiya heerka halsano ee mindhicirka 40% kana fogaada raaxo la'aanta caloosha iyo mindhicirka inta lagu jiro tababarka.

Youdaoplaceholder0 \ n \ n Cutubka Afraad: Kacdoonka Warshadaha: Dagaalka Tiknoloojiyada ee Suuqyada Trillion-dollar ?

Youdaoplaceholder0 4.1 Race Capacity: Shirkadaha Shiinaha ayaa ka gudbay qalooca

Youdaoplaceholder0 Baolingbao Bio : Maalgeli 800 milyan yuan si loo dhiso saldhigga wax-soo-saarka polyglucose-ka ugu weyn adduunka, tignoolajiyada enzymatic synthesis si loo gaaro 99.9% nadiif ah;

Youdaoplaceholder0 Hualixi Biotech ? : Kobciyay nano-fibrotic polyglucose, dareenka sharciyaynta viscosity ayaa kordhay 4 jeer, la helay ogolaanshaha cuntada caafimaadka ee gaarka ah ee NMPA;

Youdaoplaceholder0 Qaabeynta Transnational : DuPont waxay la kaashanaysaa Mayo Clinic si ay u horumariso tijaabada caafimaad ee Wajiga III ee polydextrose ee ka hortagga kansarka mindhicirka.

Youdaoplaceholder0 4.2 Caqabadaha Garashada: Farqiga u dhexeeya Shaybaadhka ilaa Suuqa Guud

Inkasta oo caddayn cilmi ah oo ku filan, cilmi-baarista macaamiisha ayaa muujinaysa in:

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Youdaoplaceholder0 Aqoonta Indho la'aanta : Kaliya 31% dadweynaha ayaa fahma farqiga u dhexeeya polydextrose iyo fiilooyinka caadiga ah;

Youdaoplaceholder0 Qiyaasta khaldan fikradaha: 45% macaamiisha ayaa si khaldan u aaminsan in "wax badan ayaa ka fiican", taas oo keeni karta raaxo la'aan sida dibiro;

Youdaoplaceholder0 Jawaabcelinta Warshadaha: Bulshada Shiinaha ee Nafaqada ayaa sii daysay Warqadda Cad ee Codsiga Polydextrose, iyada oo dejisay marin badbaado ah oo ah 15g maalintii.

Qofkastaoplaceholder0 Cutubka 5 Aragtida Mustaqbalka: Dib-u-qeexidda Fibre's 'Xuduudda Wacan'

Youdaoplaceholder0 5.1 Brain-Gut Axis Breakthrough: Buundada molecular ee mindhicirka ilaa dareenka

Tijaabooyinkii ugu dambeeyay ee xayawaanka ee Machadka Tignoolajiyada ee California ayaa helay:

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Youdaoplaceholder0 Nasinta Walaaca: Jiirarka ku jira kooxda dhexgalka polyglucose waxay kordhiyeen wakhtiga sahaminta ee tijaabada maze 53%;

Youdaoplaceholder0 Baafinta Mechanism: Butyric acid waxa uu kiciyaa muujinta BDNF ee hippocampus iyada oo loo marayo xannibaadda dhiigga-maskaxda, iyada oo kordhinaysa cufnaanta synaptik 29%.

Youdaoplaceholder0 5.2 Biology Synthetic: 'Qaabka ugu dambeeya' ee fiilooyinka la qorsheeyay

Shirkadda Ginkgo Bioworks ee Maraykanka ayaa wax ka beddeshay noocyada khamiirka iyadoo la adeegsanayo tignoolajiyada CRISPR-Cas9 si ay si toos ah u qariso "polydextrose hiddo-wadaha" oo leh hawlo habaysan:

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Youdaoplaceholder0 Beegsiga saxda ah: Waxay si gaar ah u kicin kartaa kobaca Achaemenia, fara badana waxa ay kordhisay 80% moodooyinka buurnaanta;

Youdaoplaceholder0 Jawaab caqli gal ah: Dareemaha pH-ku-dhisan, saxnaanta isbeddelka viscosity ayaa horumaray ilaa ±5 mPa·s, oo la filayo in ay gasho tijaabooyin caafimaad 2026.

Youdaoplaceholder0 Gabagabo: Marka sirdoonka molecular la kulmo Gut Ecology ?

Safarka sayniska ee polydextrose waa taariikh ka soo noqoshada "wax soo saarka warshadaha" ilaa "injineer deegaanka xiidmaha". Waxay noo sheegaysaa in horumarka dhabta ah ee caafimaadku inta badan ka yimaad dhismo qoto dheer iyo dib-u-habayn xudduudaha nuxurka ah. Sida ay tidhi Jennifer Doudna oo ku guulaysatay Nobel-ka, "Bayoolajiyada synthetic waxa ay ina baraysaa in molecules lagu siin karo 'awoodda fikirka'." Kacaankan teknoolajiyada ee caafimaadka mindhicirka, polydextrose ayaa laga yaabaa inay noqoto meesha laga bilaabo - marka "molecules caqli badan" ay ku biiraan dagaalka, bini'aadamku wuxuu ugu dambeyntii gaari doonaa tallaabooyin sax ah oo ka dhan ah cudurrada dabadheeraad.