HMB ke metabolite e bohareng ea leucine ea bohlokoa ea amino acid, 'me' mele oa motho o ka hlahisa palo e nyane ea HMB ka boeona. Lijong tse tloaelehileng, 'mele oa motho o hlahisa hoo e ka bang 300 ho 400 mg ka letsatsi, eo 90% ea eona e tsoang ho catabolism ea leucine. HMB e ka sebelisoa ho khothaletsa kholo ea mesifa, ho matlafatsa t?ireletso ea 'mele, ho fokotsa k'holeseterole le maemo a tlaase a lipoprotein' meleng ho fokotsa ho hlaha ha lefu la pelo le lefu la pelo, empa hape le ho ntlafatsa bokhoni ba 'mele ba ho lokisa naetrojene, ho boloka maemo a protheine' meleng, le ho thibela ho bola ha mesifa ho bakuli ba robetseng kapa ba shoeleng litho. Lilemong tsa morao tjena, hobane e ka fokotsa t?enyo ea mesifa ea mesifa ka mor'a ho ikoetlisa, ho lokisa mesifa ea mesifa, ho eketsa matla a mesifa le ho chesa mafura a 'mele, e fetohile motsoako oa linaleli lihlahisoa tsa phepo ea lipapali. Ho feta moo, HMB e netefalitsoe ka bongaka hore e potlakisa pholiso ea maqeba le ho thibela ho ruruha. Liphuputso li bont?itse hore Ca HMB e ka potlakisa motsoako oa protheine le ho fokotsa t?ebeliso ea protheine. Ca HMB e kopantsoeng le glutamine le arginine e ka ntlafatsa ho leka-lekana ha nitrogen e mpe ea bakuli 'me ea phetha karolo e ntle ho hlaphoheloeng ha mahlomola le ho buuoa.

Ka 2011, Lekala la Bophelo la Chaena la pele le ile la phatlalatsa tumello ea β-hydroxy-β-methylbutyrate calcium (Ca HMB) e le lijo tse ncha tsa mohloli, t?ebeliso ea lijo tsa phepo ea lipapali, lijo tse khethehileng tsa t?ebeliso ea meriana, chelete e khothalletsoang ke ≤3 grams / letsatsi. Ka 2017, Khomishene ea Naha ea Bophelo bo Botle le Thero ea Malapa e phatlalalitse katoloso ea sebaka sa kopo ea Ca HMB ho tloha lits'ebetsong tse peli tsa mantlha ho isa ho tse robong, 'me ea laela mekhatlo ea theknoloji ea tlhahlobo ea kotsi ho etsa liteko tsa polokeho. T?ebeliso ea Ca HMB e ile ea atolosoa ho kenyelletsa lino, lebese le lihlahisoa tsa lebese, lihlahisoa tsa cocoa, chokolete le lihlahisoa tsa chokolete, lipompong, lintho tse halikiloeng, le lijo tse khethehileng tsa lijo, 'me chelete e khothalletsoang e ne e ntse e le ≤3 g / letsatsi, e sa kang ea feta tekanyo ea baithaopi ba liteko tsa batho. Ca HMB e amohetsoe joalo ka GRAS ke Tsamaiso ea Lijo le Lithethefatsi ea US ka 1995 mme e sebelisoa lijong tsa phepo ea bongaka le lijong tse khethehileng. Lilemong tse 20 tse fetileng, Ca HMB e 'nile ea sebelisoa haholo lihlahisoa tsa lebese, lihlahisoa tsa chokolete, lino, litepisi tsa matla le lijo tse ling' marakeng oa US. Ca HMB ke lijo tse tala tse lumelloang ke melao ea Majapane, tse ka ekeletsoang libakeng tse ngata tse kang lijo tse tloaelehileng, lijo tsa phepo ea lipapali, lijo tsa ho theola boima ba 'mele, lijo tsa botle, joalo-joalo E ka boela ea sebelisoa e le motsoako o sebetsang ho li-supplement tsa lijo tse kang li-capsules, matlapa, lino tse thata. Bakeng sa bahlahisi le likhemisi, Ca HMB hajoale ke e 'ngoe ea lisebelisoa tsa bophelo bo botle tse tsebahalang' marakeng oa Japane.