(1) Lintho tse phelang tse etsahalang ka tlhaho

Joaloka monosaccharate ea tlhaho, mannose e fumanoe ka har'a epidermis ea liapole (0.7-1.2%) le lilamunu (0.3-0.8%). Mokhoa oa eona oa limolek'hule e ne e le ?. C?H??O? le glucose ?. 8. Nakong ea metabolism ea motho, mannose e kena liseleng ka sepalangoang se itseng, GLUT1, empa ha e kenye tsamaiso ea insulin-secreting, thepa e etsang hore e be khetho e monate e sireletsehileng bakeng sa batho ba nang le lefu la tsoekere ?78.

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(2) Ho phahama ha li-additives tse ncha tsa lijo

Ka 2023, Khomishene ea Naha ea Bophelo e ile ea thathamisa konjac mannose oligomeric e le thepa e ncha ea lijo, e t?oaeang ho kena ka molao ha mannose t?imong ea kopo ea indasteri ea lijo 7. Tekanyo ea polymerization ea mannose oligosaccharide e fumanoang ke enzymatic hydrolysis ea konjac glucomannan e laoloa ka har'a li-unit tsa tsoekere tse 2-10, tse sa bolokeng thepa ea tlhaho feela empa hape li na le ho ikamahanya le maemo. 7 e sebelisitsoe mefuteng e fetang 20 ea lijo joalo ka lino tse se nang tsoekere le li-biscuits tse sebetsang.

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Ea bobeli, mokhoa o matlafatsang oa mannose

(a) mokoallo oa tlhaho oa tsamaiso ea moroto

Lintlha tsa bongaka li bonts'a hore 2g ea mannose ka letsatsi e ka fokotsa ts'oaetso ea khafetsa ea ts'oaetso ho basali ka 38% 8. Mokhoa oa eona oa ts'ebetso o kenyelletsa:

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ho tlosoa ha 'mele : 90% ea ho noa e nt?oa ka urethra nakong ea metsotso e 30-60, 'me libaktheria tsa pathogenic (joaloka E. coli) li nt?oa 'meleng 8;

biofilm cracking ?: senya β-1, 4-glucoside bond ea bacterial biofilm, ntlafatsa katleho ea baktheria ea lithibela-mafu ka makhetlo a 3 78;

taolo ea 'mele ea ho it?ireletsa mafung: ho khothaletsa tlhahiso ea defensin ka lisele tsa urethral epithelial, ho matlafatsa sesole sa lehae8.

(2) Mohlokomeli ea sa bonahaleng oa bophelo bo botle ba mala

Konjac mannooligosaccharide e ka atisa li-probiotics tse kang bifidobacterium, 'me ea eketsa bongata ba limela tsa mala ka 25% 7. Tekong ea tleliniki Sepetleleng sa Wuhan Union Medical College, kamora ho noa mannose oligosigro bakeng sa libeke tse 4, khafetsa ea ho nt?a mala a eketsehile ho tloha makhetlo a 2.3 ho isa ho a 4.1 ka beke, mme sekhahla sa ho tsoa ka mpeng se theohile ka 62% 7.

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(3) Sesebelisoa sa ho thibela le ho laola mafu a metabolism

Ho fapana le li-sweeteners tsa maiketsetso, mannose e na le index ea glycemic (GI) ea 0, 'me ho nkela sucrose linthong tse besitsoeng ho fokotsa tlhōrō ea tsoekere ea mali ka 2.1mmol/L ho bakuli ba lefu la tsoekere ?78. Phuputso ea 2024 Journal of Nutrition e netefalitse hore mannose e ntlafatsa mamello ea tsoekere ho bakuli ba hanyetsanang le insulin 7 ka ho kenya t?ebetsong tsela ea AMPK.

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3.Litloaelo tse ncha indastering ea lijo

(1) Mehlala ea ntlafatso ea lijo tse sebetsang

lino tse sireletsang ho nt?a metsi : 500mg/ botlolo ea mannose oligosaccharide e kentsoe senoeng sa cranberry complex sa mofuta o itseng, 'me theko ea thekiso e feta linyeoe tse limilione tse 2 halofong ea pele ea selemo sa 7;

Bakery e laolang tsoekere : bohobe bo nkelang lijo bo entsoeng ka konjac le mannose-oligosaccharide bo na le lik'habohaedreite tse ka tlase ho 45% le fiber e fetang makhetlo a mararo ho feta 7;

Matlafatso ea phepo e nepahetseng bakeng sa bana : Lithupa tsa chisi tse kentsoeng mannose li ka khothaletsa sekhahla sa ho monya calcium ka 18%, e kenyellelitsoeng tsamaisong ea 30% ea phepelo ea lijo tsa kindergarten 7.

(2) Khatelo-pele ea ho sebetsana le boqapi ba theknoloji

Theknoloji e tsamaisitsoeng ea enzymatic hydrolysis e ntlafalitsoeng ke likhoebo tsa Hubei e ekelitse sekhahla sa phetoho ea konjac glucomannan ho tloha ho 58% ho isa ho 92%, le ho fokotsa lit?enyehelo tsa tlhahiso ka 40% 7. Ts'ebeliso ea ts'ebetso ea microencapsulation e atolositse botsitso ba mannose ho metsotso e 60 ho 120 ℃, mme e atolositse ts'ebeliso ea eona t?imong ea ho baka 78.

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4.Tlhahiso ea saense le ts'ebeliso e utloahalang

(1) Molao oa Khauta oa ho laola lethal dose

Tekanyo ea t?ireletseho: ho ja ha 'ngoe ha ho fete 3g, ho noa letsatsi le leng le le leng ho laoloa ka hare ho 5g, ho feteletseng ho ka baka ho ruruha ka mpeng, lets'ollo (keketseho ea hoo e ka bang 7%) 8;

Tlhokomeliso e khethehileng ea baahi : bakuli ba nang le bothata ba ho fufuleloa ba renal sekhahla sa ho nt?a metsi se theohile ka 50%, ba hloka ho sebelisa 8 tlas'a tataiso ea ngaka;

Synergistic scheme : Ha e kopantsoe le cranberry extract, antibacterial effect e eketsehile ka makhetlo a 2.3 8.

(2) Ho iphetola ha indasteri ea litekanyetso tsa ho t?oaea

Melao e Akaretsang ea ho Ngola Lijo tse Phethahetseng Pele tse Pakiloeng joalokaha e fetotsoe ka 2024 e hloka:

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Mannose e tla t?oauoa ka thoko lethathamong la metsoako 'me e ke ke ea tsoakoa le lentsoe le akaretsang "sweetener" 7;

Likopo tsa mosebetsi li hloka ho t?oauoa "eseng bakeng sa kalafo e 'ngoe ea lithethefatsi" 8;

Tekanyetso ≥1g/100g e lokela ho t?oauoa "e ka baka bohloko bo fokolang ba mala" 7.

1.Likhohlano le litebello tsa nako e tlang

(1) Tsepamiso e teng ea khang

Liphello tsa nako e telele tse lokelang ho hlokomeloa : liphello tsa nako e telele tsa ho noa ho tsoelang pele ka lilemo tse fetang 5 ho limela tsa mala ha li hlake 7;

Tlhaho : Hore na ts'ebetso ea enzymatic hydrolysis e fetola thepa ea bohlokoa ea lintho e baka lipuisano tsa thuto 7;

Liphello tsa ketane ea tikoloho : Katoloso ea temo ea Konjac e lebisitse phetohong ea 30% ea mobu oa lijalo oa setso, e leng se ka amang mefuta-futa ea lihloliloeng 7.

(2) Tataiso ea tsoelo-pele ea theknoloji

Ts'ebeliso e nepahetseng : Nts'etsopele ea lihlahisoa tsa mannose tse ikhethileng mefuteng e fapaneng 8;

tlhahiso e tala ?: Mefuta ea Konjac e ntlafalitsoeng ke theknoloji ea CRISPR, litaba tsa glucomannan li eketsehile ho tloha 60% ho ea ho 85% 7;

Tlhokomelo e bohlale : Sesebelisoa se aparoang se beha leihlo khatello ea moroto ka nako ea 'nete bakeng sa tlatsetso ea motho 8.

Qetello

E le mohlala oa ho kopanngoa ha tlhaho le theknoloji, mannose ha e tsoele pele bohlale ba boholo-holo tlas'a sefate sa apole feela, empa hape e khant?a leseli la boenjiniere ba kajeno ba lijo. Tlas'a tataiso ea leano la Healthy China 2030, tlatsetso ena e sebetsang le e bolokehileng e hlophisa bocha meeli ea kutloisiso ea batho ea li-additives tsa lijo. Leha ho le joalo, hoa hlokahala ho hlokomela hore t?ebeliso e utloahalang ea tlatsetso leha e le efe e lokela ho thehoa lijong tse leka-lekaneng, joalokaha "Li-additives tse ke keng tsa qojoa" li re: "Saense le theknoloji li entse hore lijo li khonehe, empa ho hlompha tlhaho e 'nile ea e-ba motheo oa indasteri ea lijo.