Lefapheng la litsebi tsa phepo e nepahetseng,vithamine Ee t?oana le "spearhead" ea maverick. Boholovithaminelitloaelo li sebetsa e le coenzyme ka liphetoho tsa lik'hemik'hale, li bapala karolo e thusang, 'me vithamine E e ikhetha, e nang le matla a eona a matla a ho sireletsa bophelo bo botle ba batho. Vithamine E ke ea bohlokoae qhibilihang ka mafuravithamine lelapa 'me ke derivative ea benzodihydropyrane e nang le sebopeho se t?oanang le mosebetsi oa likokoana-hloko, haholo-holo ho akarelletsa tocopherol le tocotrienol. Sehlopha se seng le se seng se arotsoe ka li-subtypes tse 'nè, α, β, γ le δ, ho ea ka phapang ea boemo ba methyl ka lesale la benzopyrane, kakaretso ea mefuta ea 8, 'me li-isomer tsena li na le matla a antioxidant. Li-radicals tsa mahala ke sehlopha sa limolek'hule tse sa tsitsang tse nang le ts'ebetso e phahameng haholo ea lik'hemik'hale tse hlahisoang ts'ebetsong ea metabolism ea 'mele. Leseli la ultraviolet, t?ilafalo ea tikoloho le lintlha tse ling tse ka ntle li ka etsa hore ho be le li-radicals tsa mahala, 'me mitochondria hape ke sebaka sa tlhahiso ea mahala ea radical ha lisele li etsa metabolism ea aerobic ho fana ka matla. Li-radicals tsa mahala tse feteletseng li baka khatello ea oxidative, e hlaselang li-macromolecules tsa tlhaho tse kang lipids, liprotheine le DNA ka har'a lisele, e leng se bakang t?enyo ea oxidative. Ka linako tse mahlonoko, vithamine E e it?etlehile ka sebopeho sa eona sa phenolic hydroxyl ho fana ka liathomo tsa haedrojene ho sebetsana le li-radicals tsa mahala, ho fokotsa li-radicals tsa mahala, ho sitisa ketane ea oxidative, kahoo ho sireletsa lisele.

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Ho qhibiliha ha mafura ha vithamine E ho etsa hore e ajoa ka mokhoa o khethehileng libakeng tse nang le lipids tse ngata, joalo ka lisele tsa lisele le lipoprotein. Libakeng tsena, e thibela ka matla lipid peroxidation. Ha li-radicals tsa mahala li hlasela mafura a polyunsaturatedacid, e bakang ketane ea lipid peroxidation e senyang li-membrane tsa sele le lipoprotein, vithamine E e ka emisa karabelo nakong ea ho qala le ho fetisetsa, ho sireletsa lipids ka maleng, mali, lisele le lisele tsa lisele. Ka tsamaiso ea methapo ea pelo,vithamine Ee fokotsa tlhahiso ea oxidized low-density lipoprotein ka phello ea antioxidant, e fokotsa t?enyo ea eona ho lisele tsa vascular endothelial, ebe e thibela sebopeho le nts'etsopele ea letlapa la atherosclerotic. Ka nako e ts'oanang, vithamine E e ka boela ea laola ho ata le ho falla ha lisele tsa mesifa ea mesifa e boreleli ho boloka tsitsipano e tloaelehileng le elasticity ea methapo ea mali. Vitamin E e boetse e phetha karolo ea bohlokoa taolong ea 'mele ea ho it?ireletsa mafung. E khothalletsa ho ata le ho arohana ha lisele tsa 'mele tsa ho it?ireletsa mafung tse kang T le B lymphocyte, ho matlafatsa t?ebelisano pakeng tsa lisele, le ho matlafatsa karabelo ea 'mele ea ho it?ireletsa mafung. Ka nako e ts'oanang, e kenya letsoho taolong ea phetisetso ea lisele tsa 'mele oa ho it?ireletsa mafung, e ama secretion le polelo ea li-cytokine, hape e laola karabelo ea 'mele ea ho it?ireletsa mafung. Mehloli e meholo ea tlhaho ea vithamine E e kenyelletsa oli ea meroho, linate, lipeo le meroho e makhasi a matala. Har'a mehloli ena, oli ea meroho ke eona e ruileng ka ho fetisisa ea vithamine E, haholo-holo e le alpha-tocopherol. Ho phaella moo, ho na le li-supplement tsa multivitamin E 'marakeng, ho akarelletsa le softgel, matlapa a chewable le litlolo, tse loketseng litlhoko tsa lihlopha tse fapaneng tsa batho. Ho ipapisitsoe le lit?upiso tsa phepo ea limatlafatsi, tekanyetso e khothalletsoang ea vithamine E bakeng sa batho ba baholo ke 15 mg ka letsatsi (e lekantsoe ka alpha-tocopherol e lekanang). Leha ho le joalo, lintlha tsa 'nete tsa lipatlisiso li bont?a hore karolelano ea vithamine E e jeoang ke batho ba baholo ka lijo tsa bona tsa letsatsi le letsatsi hangata e ka tlase ho 10 mg. Liphuputso tse ling li bont?itse hore kalafo ea adjuvant bakeng sa mafu a itseng a kang ho lieha ho tsofala le ho ntlafatsa ho senyeha ha kelello, ho tlatsetsa 200-800 mg ea vithamine E letsatsi le leng le le leng ho ka ba le phello e itseng. Ka kakaretso, vithamine E ea molomo e bolokehile, empa ho ja nako e telele (ho feta 1,000 mg ka letsatsi) ho ka eketsa menyetla ea ho ba le liphello tse mpe tse kang kotsi ea mali. Ka hona, ha u sebelisa li-supplement tsa vithamine E, ke habohlokoa ho latela keletso ea litsebi ho netefatsa polokeho le mabaka a utloahalang a tlatsetso.