0102030405
????? B12 ?? Hydroxycobalamin ??? ??? ???? ???
?????
Hydroxycobalamin (ohcbl? ?? B12a) ????? B12 ?? ??? ????? ??? ??? ?? ????? B12 ?? ?????? ??? ?? ??? ??? ?? cobalamine ???? ?? ?????? ??? ??? ??? ?? ???????? ?? ????? ???? ???? ??? ?????? ??? ?? ?????????????????? ?? ??? ??? ????? B12 ???? ???? ???? Hydroxycobalamin ???? ??? ??? ?????? ??? ??? ????? ?? 12 ??? ??? ?? ??????????????????? ?? ??? ??? ????? ???? ???? ??? ????? ??????? ???? hydroxycobalamin ????? ?? ????? B12 ?? ??? ???? coenzyme ??? ??? ????? ?? ???? ??? ????? ?? ??????????????????? ?????? ?? ?? ?????? ?? ??? ?????? ??? ?? ????? ?? ??? ??? ????????? ??? ?? ???? ?? ??? ??????? ???? ?? (?????? ?? ????????? ????? ?? ???? ?????? ????? ??)? Hydroxycobalamin ??? ??? ????? ?? ??? ?? ??????? ??? ???? ??.
????? 2
?????
?? ??? ????? API ?????? ??? ????? ?? 12 ?? ??? ????? ???? ?? ???????????????????? ???????????? ??????????? ??? ????????? ???????? ???? ?? ?? ??? ?? ?? ?? B12 ???????? ??? ????? ??? ?? ????? ?????? ???? ???? ???? ?? ??? ??? ????? ????? ?? ????? ???? ??? Hydroxycobalamin ?? hydroxycobalamin ??? ???? ?? ?????? B12 ?? ????? ??? ??????????? ???? ?? ??? ??? ??? ??? B12 ????????? ??? ??? ??????????????????? ???? ??? ?????? ?? ????? ??? ????? ??? ??? ????????? ????? ??? ??? ???? ???? ???????? ??? ??? ???? ??? ????? ??? ?? ??? cyanocobalan ??? Mecobalamin ?? ?????? ??? ???? ??? ???? ???? ??? ?? ?? ?????? ??? ????? ??? ?? ???? ?????? ?? ???? ?? ?? ??? ?? ???? ?? ??? ???? ????? ?? ????? ?? ???? ??? ????? ??? ?? ??? ?? ???? ???? ????????? ?? ?? ?? ??? ??? ???? ?? ??? ???? ??? ?? ?? ?????? ??????????????????? ???? ??? ?? ??? ????????? ?? ???? ?? ?? ???? ?? ????? ??? ??? ?????? ????????????? ??? ???? ??? ?? ??? ?? ?? ????? ???? ??? ????????? ??? ?? ????? ???
??????? ?? ???????
????? | ??????? | ????? |
?????? ??? ??????? ????? | ||
????? ??? | ???? ??? ?? ????? ????? | ????? ???? ??? |
????? | 361±1nm? 550±2nm ?? ????? ?? ????? ??? ????? | ????? ???? ??? |
??? ???? ?? ????? | ≤12% | 9.0% |
???? | 09.0%-1.3% | 1% |
?????? ?? ?????? | ≤0.1% | 0.06% |
???? ???? | ||
?????? (As) | ≤0.1mg/kg | ????? ???? ??? |
??? (Pb) | ≤1mg/kg | ????? ???? ??? |
??????????????? ???? | ||
?? ???? ?? ???? | ≤1000cfu/g | ????? ???? ??? |
???? ??? ???? | ≤100cfu/g | ????? ???? ??? |
???????? | ???? | ???? |
?? ???? | ???? | ???? |
????????? | ???? | ???? |
Staphylococcus | ???? | ???? |
????? ??????? | ||
?????: 25 ??????? / ????? | ||
?????: ??????? ?? ??? ??? ????? ??? ?? ????? ??? ???? ?????? ??? ???? ???? ?? ?????? ????? ?? ??????? ????? ?? ????? ?? ?????? ??? ???? ??????? ?? ????? ?????? | ||
???? ????? | 3 ??? | |