I-Vitamin E (i-Vitamin E) liqela leevithamini ezinyibilikayo ezinamafutha aqukethe i-α, β, γ, δ-tocopherol kunye ne-tocotrienol. Sisakhamzimba esibalulekileyo ukuba umzimba awukwazi ukuzenzela ngokwawo, kwaye yenye yezona antioxidants zibalulekileyo 12.
Ulwakhiwo lweekhemikhali luqukethe amakhonkco e-benzopyrane kunye namatyathanga asecaleni e-hydrophobic, anika i-lipid membrane ukungena kwi-67.
Iimpawu zomzimba kunye neekhemikhali

Ukunyibilika : ukunyibilika kumafutha, i-ethanol kunye nezinye izinyibilikisi eziphilayo, ezinganyibilikiyo emanzini 12.
Uzinzo : ukumelana nobushushu (≤200 ° C) kunye neendawo ezineasidi kodwa zinobuntununtunu kwialkali, ioksijini, imitha ye-UV kunye neeyoni zentsimbi (Fe3 + + /Cu2 +). Ukuqhotsa kuwonakalisa kakhulu umsebenzi

Okokuqala, inkqubo ye-antioxidant synergistic ye-radical free scavenging circulatory system

I-Vitamin E, njenge-antioxidant ene-fat-soluble, ikhetha ngokufanelekileyo i-lipid free radicals kwi-membrane yeseli, ngelixa i-vitamin C, njenge-antioxidant e-soluble yamanzi, iyanciphisa kwaye ihlaziye i-vitamin E ene-oxidized (i-tocopherol free radicals), eyenza umjikelezo oqhubekayo we-antioxidant 17.
Iimvavanyo zibonisa ukuba ukudibanisa kwezi zibini kunokuphucula ukusebenza kwe-antioxidant ngamaxesha e-3, i-molecule enye i-vitamin E ingakwazi ukususa ngokuqhubekayo ukuya kwi-4 i-radicals yamahhala, i-vitamin C ngokusebenzisa indlela yokuvuselela ukwandisa ixesha layo lesenzo 78.

Uthungelwano loKhuselo lwesiGaba esiPhakathi

I-Vitamin E iqinisa i-lipid bilayer ye-membrane yeseli kwaye ithintela i-lipid peroxidation chain reaction. I-Vitamin C ikhupha i-radicals yasimahla enyibilikayo emanzini kwi-cytoplasmic matrix ukwenza inkqubo yokukhusela i-lipid-water biphasic 13.

Okwesibini, i-immune system bidirectional activation effect iphakamisa ukungatheleleki okungaphakathi: I-Vitamin C ikhuthaza i-neutrophil chemotaxis, i-vitamin E iphucula umsebenzi weeseli ze-NK, kwaye ukudibanisa kunciphisa iziganeko zokusuleleka kwendlela yokuphefumula nge-32% 15.
ilawula i-adaptive immune immune : i-synergistically ivuselela ukwanda kwe-T lymphocyte, iphucula ukusebenza kakuhle kwemveliso ye-antibody ngama-28%, kwaye ibe nefuthe elihle kwimpendulo yesitofu sokugonya 57.

Okwesithathu, indlela yokungenelela edibeneyo yezempilo yesikhumba

Ukhuseleko lokufota

I-Vitamin E inqanda i-sepiperoxidation eyenziwe yi-UV kunye ne-vitamin C ivimba umsebenzi we-tyrosinase, i-enzyme ephambili kwi-melanin synthesis, kunye nokudibanisa kunciphisa izinga le-erythematosis yesikhumba nge-54% 24.

Ukulawulwa kwe-collagen metabolism

I-Vitamin C ivuselela i-prolyl hydroxylase ukukhuthaza i-collagen synthesis, kwaye i-vitamin E inciphisa umsebenzi we-collagenase ukukhusela ukuthotywa. Ulingo lwezonyango lubonise ukuba ukuqina kwesikhumba kuphuculwe ngama-23% kwaye ubunzulu bombimbi buncitshiswe nge-19% 34.

4. Indlela yokubambisana yokhuseleko lwentliziyo
Ungenelelo lwe-atherosclerosis ye-atherosclerosis : I-Vitamin E inqanda i-oxidation ye-low-density lipoprotein (LDL) kunye ne-vitamin C yokulungiswa kwe-vascular endothelium eyonakeleyo ngokudibanisa ne-18% yengozi ephantsi yeziganeko ze-cardiovascular 15.
ukuphuculwa kwe-microcirculation : ivithamin E yehlisa ukudityaniswa kweplatelet engaqhelekanga, ivithamin C yonyusa ukuqina kwe-capillary, kwaye inexabiso lothintelo oludibeneyo kunye nonyango lwe-retinopathy yesifo sikashukela 58.

5. Iimpawu ze-Metabolic cooperative optimization
Ukulawulwa kwe-iron metabolism : I-Vitamin C iya kunciphisa isinyithi esine-trivalent kwintsimbi ye-bivalent, iphucule izinga lokufunxa amaxesha angama-2-3; I-Vitamin E ikhusela ukuzinza kwe-erythrocyte membrane kwaye inciphisa umngcipheko we-hemolysis 57.
I-cholesterol balance : I-Vitamin E inqanda i-HMG-CoA reductase ukunciphisa i-cholesterol synthesis, i-vitamin C ikhuthaza ukukhutshelwa kwe-bile acid, kwaye ngokudibeneyo kunciphisa amanqanaba e-cholesterol epheleleyo nge-12% -15%