I-sodium hyaluronate isebenza njenge-lubricant yezicubu kwaye ithathwa njengedlala indima ebalulekileyo ekulawuleni intsebenziswano phakathi kwezicubu ezikufutshane. Yenza isisombululo se-viscoelastic emanzini. I-viscosity ephezulu yesisombululo inikeza ukukhuselwa komatshini kwizicubu (iris, retina) kunye neeseli zeeseli (i-cornea, i-endothelium, kunye ne-epithelium). I-elasticity yesisombululo inceda ukufunxa uxinzelelo lomatshini kunye nokubonelela nge-buffering yokukhusela izicubu. Ekukhuthazeni ukuphiliswa kwesilonda, kukholelwa ukuba isebenze njengesixhobo sothutho sokukhusela, ukuzisa izinto zokukhula kwe-peptide kunye nezinye iiprotheni zesakhiwo kwindawo yesenzo. Emva koko ukuthotywa kwe-enzymatic kunye nokukhululwa kweeprotheni ezisebenzayo ukukhuthaza ukulungiswa kwezicubu.