(1) Izinto ezenzeka ngokwemvelo

Njenge-monosaccharate yendalo, i-mannose ifunyenwe kwi-epidermis yama-apula (0.7-1.2%) kunye nama-oranges (0.3-0.8%). Indlela yayo yeemolekyuli yayiyi-?. C?H??O? kunye neglucose ?. 8. Ngexesha le-metabolism yomntu, i-mannose ingena kwiiseli nge-transporter ethile, i-GLUT1, kodwa ayisebenzisi inkqubo yokukhupha i-insulin, ipropathi eyenza kube yinto ekhuselekileyo yokuzikhethela kwi-diabetics 78.

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(2) Ukunyuka kwezongezo zokutya okutsha

Ngo-2023, iKhomishoni yezeMpilo yeSizwe idwelise i-konjac mannose oligomeric njengento entsha yokutya ekrwada, ephawula ukungena ngokusemthethweni kwe-mannose kwindawo yesicelo soshishino lokutya ?7. Iqondo lepolymerization ye-mannose oligosaccharide efunyenwe yi-enzymatic hydrolysis ye-konjac glucomannan ilawulwa ngaphakathi kweeyunithi ze-2-10 zeswekile, ezingagcini nje kuphela iipropati zendalo kodwa zikwazi ukulungelelanisa ukulungelelanisa. I-7 isetyenziswe kwiintlobo ezingaphezu kwe-20 zokutya ezifana neziselo ezingenaswekile kunye neebhiskithi ezisebenzayo.

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Okwesibini, indlela yokuxhobisa esempilweni yemannose

(a) umqobo wendalo wendlela yomchamo

Idatha yeklinikhi ibonisa ukuba i-2g ye-mannose ngosuku inokunciphisa iziganeko zokusuleleka ngokuphindaphindiweyo kwi-urinary tract kubasetyhini nge-38% 8. Indlela yokusebenza kwayo ibandakanya:

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Ukukhutshwa komzimba : I-90% ye-intake ikhutshwe nge-urethra ngaphakathi kwe-30-60 imizuzu, kunye neebhaktheriya ze-pathogenic (ezifana ne-E. coli) zikhutshwe emzimbeni 8;

Ukuqhekeka kwe-biofilm : ukutshabalalisa i-β-1, i-4-glucoside bond yebhaktiriya ye-biofilm, ukuphucula ukusebenza kakuhle kwe-bactericidal ye-antibiotics ngamaxesha angama-3 78;

Ulawulo lokhuselo lomzimba : khuthaza ukukhuselwa kwe-defensin ngeeseli ze-epithelial ze-urethral, ??ukuphucula ukhuseleko lwendawo 8.

(2) Umgcini ongabonakaliyo wempilo yamathumbu

I-Konjac mannooligosaccharide inokwandisa iiprobiotics ezifana ne-bifidobacterium, kwaye yandise ubuninzi bezityalo zamathumbu ngama-25% 7. Kulingo lwezonyango kwisibhedlele saseWuhan Union Medical College, emva kokuthatha i-mannose oligosigro kangangeeveki ezi-4, ukuphindaphindeka kokukhutshwa kwamathumbu kwanda ukusuka kwi-2.3 ukuya kumaxesha angama-4.1 ngeveki, kwaye izehlo zokuphuma kwesisu zehle nge-62% 7.

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(3) Isixhobo sokuthintela kunye nokulawulwa kwezifo ze-metabolic

Ngokungafaniyo ne-sweeteners yokwenziwa, i-mannose ine-glycemic index (GI) ye-0, kwaye ithatha indawo ye-sucrose kwizinto ezibhakiweyo zinciphisa i-postprandial iswekile yegazi nge-2.1mmol / L kwizigulane ze-diabetes 78. I-2024 Journal of Nutrition study iqinisekisile ukuba i-mannose iphucula ukunyanzeliswa kwe-glucose kwizigulane ezixhathisa i-insulin ?7 ngokuvula indlela ye-AMPK.

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3.Izenzo ezitsha kushishino lokutya

(1) Imizekelo yophuhliso lokutya olusebenzayo

Iziselo zokukhusela umchamo : I-500mg / ibhotile ye-mannose oligosaccharide yongezwa kwisiphuzo se-cranberry esiyinkimbinkimbi ye-brand ethile, kwaye umthamo wokuthengisa udlule kwi-2 yezigidi zeemeko kwisiqingatha sokuqala sonyaka 7;

indawo yokubhaka yokulawula iswekile : isonka endaweni yokutya esenziwe nge-konjac kunye ne-mannose-oligosaccharide ine-45% encinci ye-carbohydrate kunye ne-fiber ephindwe kathathu ngaphezulu kwe-7;

Ukuqinisa isondlo kubantwana : Izinti zeshizi ezinemannose ezongeziweyo zingakhuthaza izinga lokufunxa i-calcium nge-18%, efakwe kwi-30% yenkqubo yokubonelela ngokutya kwe-kindergarten 7.

(2) Ukuphumelela ekuqhubeni iteknoloji entsha

Itekhnoloji eqondisiweyo ye-enzymatic hydrolysis ephuhliswe ngamashishini e-Hubei inyuse izinga lokuguqulwa kwe-konjac glucomannan ukusuka kwi-58% ukuya kwi-92%, kwaye yanciphisa iindleko zemveliso nge-40% 7. Ukusetyenziswa kwenkqubo ye-microencapsulation kwandise ukuzinza kwe-mannose ukuya kwimizuzu engama-60 kwi-120 ℃, kwaye yandisa isicelo sayo kwintsimi yokubhaka i-78.

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4.Ingqiqo yenzululwazi kunye nokusetyenziswa okunengqiqo

(1) UMthetho Omkhulu wolawulo lwethamo

Umda wokhuseleko : i-intake eyodwa ayidluli i-3g, ukuthathwa kwansuku zonke kulawulwa ngaphakathi kwe-5g, ukugqithisa kunokubangela ukugqithiswa kwesisu, isifo sohudo (iziganeko ezimalunga ne-7%) 8;

Isilumkiso esikhethekileyo sabemi : ukusilela kwezintso izigulane zehle nge-50%, kufuneka zisebenzise i-8 phantsi kwesikhokelo sikagqirha;

Iskimu se-Synergistic : Idityaniswe ne-cranberry extract, i-antibacterial effect inyuke ngama-2.3 amaxesha 8.

(2) Imveliso yenguqu yemigangatho yokumakisha

IMithetho Jikelele yokuFakwa kweLebhile yeSondlo sokuTya kwaseKupakishweni njengoko ilungisiwe ngo-2024 ifuna:

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Imannose iya kumakishwa ngokwahlukeneyo kuluhlu lwezithako kwaye ayiyi kuxutywa negama eliqhelekileyo elithi "sweetener" 7;

Amabango omsebenzi kufuneka aphawulwe "kungekhona unyango olulolunye lwechiza" 8;

Idosi ≥1g/100g kufuneka imakishwe "kusenokubangela ukungaphatheki kakuhle kwamathumbu" 7.

1.Iingxabano kunye nethemba elizayo

(1) Ingqwalasela ekhoyo yempikiswano

Iimpembelelo zexesha elide eziza kubonwa : Imiphumo yexesha elide yokuthatha ngokuqhubekayo ngaphezu kweminyaka eyi-5 kwi-intestinal flora ayicaci 7;

Ubume bendalo : Ingaba inkqubo ye-enzymatic hydrolysis itshintsha iimpawu ezibalulekileyo zezinto ezibangela iingxoxo zezifundo 7;

Iimpembelelo zekhonkco leekholoji : Ukwandiswa kokulima kweKonjac kukhokelele kwinguqu ye-30% yomhlaba wezityalo zesiqhelo, ezinokuchaphazela i-biodiversity 7.

(2) Isalathiso sophuhliso lwezobuchwepheshe

ukuchaneka kwesicelo : Ukuphuhliswa kwezinto eziphuma kwimannose ezikhethekileyo kwiintlobo ezahlukeneyo 8;

imveliso eluhlaza ?: Iindidi ze-Konjac eziphuculwe ngeteknoloji ye-CRISPR, umxholo weglucomannan unyuke ukusuka kwi-60% ukuya kwi-85% 7;

Ukujongwa ngobukrelekrele : Isixhobo esinxitywayo sijonga ukugxilwa kwe-urinary mannose ngexesha lokwenyani lolongezelelo lomntu 8.

Ukuqukumbela

Njengomzekelo wokuhlanganiswa kwendalo kunye nobuchwepheshe, i-mannose ayiqhubeki nje ubulumko bamandulo phantsi komthi we-apula, kodwa iphinde ikhanyise ukukhanya kobunjineli bokutya banamhlanje. Ngaphantsi kwesikhokelo se-Healthy China 2030 isicwangciso, esi songezo esisebenzayo nesikhuselekileyo silungisa kwakhona imida yokuqonda kwabantu malunga nezongezo zokutya. Nangona kunjalo, kuyimfuneko ukuqaphela ukuba ukusetyenziswa okunengqiqo kwanoma yimuphi ukongeza kufuneka kusekelwe kukutya okunokulinganisela, njengoko "Izongezo zokutya ezingenakuphepheka" zithi: "Inzululwazi kunye nobuchwepheshe buye benza ukutya kube lula, kodwa ukuhlonipha indalo kuye kwahlala kusisiseko soshishino lokutya.