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Ukulungiselela indlela ye-HMB-Ca
2025-03-17
Indlela yoku-1:
Ukusebenzisa i-4-methyl-4-hydroxy-2-pentanone (i-diacetone alcohol) njengento yokuphendula, amanzi njenge-solvent, isisombululo se-NaOBr samanzi sasisetyenziselwa ukusabela kwe-halogenated, kulandelwa yi-acidification kunye ne-isobutanol extraction. I-asidi ye-HMB kwi-extract isobutanol yayifakwe ityuwa ngokuthe ngqo kunye ne-Ca (OH) i-2 ukufumana i-β - hydroxy - β - methylbutyrate calcium. Le ndlela ineenzuzo zokucoceka kwemveliso ephezulu kunye nongcoliseko oluphantsi lokusingqongileyo.
- Indlela yesi-2:I-1) Ukusabela kwe-glacial acetic acid, i-sulfuric acid, kunye ne-H2O2, ilandelwa yi-vacuum distillation, ivelisa isisombululo se-peracetic acid;
- 2) Xuba imveliso efunyenwe kwinyathelo 1) kunye ne-diacetone alcohol, yongeza i-methyl acetate njenge-solvent yokusabela, uze udibanise kwaye uqokelele i-70 ℃ iqhezu. Intsalela emva kwe-distillation isisombululo se-β - hydroxy - β - methylbutyric acid;
- I-3) Yongeza amanzi kunye nesisombululo se-sodium hydroxide kwi-residu ye-distillation efunyenwe kwinqanaba le-2) ukulungisa i-pH kwi-6.0-7.0. Fudumeza kwaye unyibilikise umxube, uze uwuhluze. Yongeza i-calcium chloride kwi-filtrate, ugxobhoze ukusabela, kwaye ulungelelanise i-pH kwi-6.5-7.0 kwakhona ukuze i-precipitate β - hydroxy - β - methylbutyrate calcium. Hlunga kwaye womise ukufumana imveliso