Iti sesinye sezona ziselo zidumileyo kwihlabathi, ngakumbi eTshayina. I-tea e-China ayilona nje isiselo, kodwa kunye nesimboli sendlela yokuphila kunye nenkcubeko.

Ukusela iti kuthathwa njengendlela yokuphila esempilweni kuba iti iqulethe iintlobo ngeentlobo zeekhompawundi eziluncedo, ezinje ngeecatechin, iti polyphenols kunye necaffeine. Izifundo ezininzi zibonise ukuba isicatshulwa seti sinokuthintela umhlaza, ukwandisa ubomi, ukunciphisa umngcipheko woxinzelelo lwegazi, isifo seswekile, isifo senhliziyo njalo njalo.

Isifo sesibindi esinamafutha angasinxilisayo (NAFLD) luhlobo oluqhelekileyo lwesifo sesibindi esingapheliyo e-China, kunye nezigulane ezingaphezu kwe-150 yezigidi. Okwangoku, akukho ziyobisi ezivunyiweyo ukunyanga isifo sesibindi esinamafutha angenatywala, kwaye izigulane zinokungenelela kuphela ngotshintsho lokutya kunye nokuzivocavoca. Ngoko ke, kukho imfuneko engxamisekileyo yokuphuhlisa izicwangciso ezintsha zonyango.

Kutshanje, Abaphandi abavela kwiYunivesithi yezoNyango yaseChina bapapashe iphepha elinesihloko esithi "I-Epigallocatechin gallate inciphisa isifo sesibindi esinamafutha anganxiliyo" kwiphephancwadi i-Clinical Nutrition ngokusebenzisa ukuvinjelwa kwentetho kunye nomsebenzi we-Dipeptide kinase 4 ".

Olu pho nonongo luqinisekisiwe ngezilingo zeklinikhi ezilawulwa ngokungahleliwe, iimvavanyo zezilwanyana kunye novavanyo lwe-in vitro ukuba i-EGCG, eyona nto iphambili ye-bioactive kwi-tea eluhlaza, inceda ekuphuculeni isibindi esinamafutha, i-ECGC inqanda ukuqokelelwa kwe-lipid, inqanda ukuvutha, ilawula i-lipid metabolism, ikhusela umonakalo wesibindi, kwaye iphucula i-non-alcoholic fatty expression4 inhibiting ye-dipepting yesibindi. (DPP4).

I-Dipeptide kinase 4 (DPP4), i-protease eqhekeza uluhlu lwe-substrates kwi-cell surface, iye yaqokelela ubungqina bokuba i-DPP4 idlala indima ekuphuhlisweni kwe-NAFLD, kunye nezigulane ze-NAFLD zibonisa umsebenzi ophezulu we-plasma we-DPP4 xa kuthelekiswa nabantu abaphilileyo.

Kolu phononongo, abaphandi bahlalutya ukuphumelela okunokwenzeka kwe-EGCG kwizigulane ezine-NAFLD ngokusebenzisa iimvavanyo zekliniki ezilawulwa ngokungahleliwe, zabona ukuphuculwa kwe-EGCG kwisibindi seempuku zemodeli ngokusebenzisa iimvavanyo zemodeli yezilwanyana, kwaye bahlalutya indlela yokuphucula i-EGCG kwi-NAFLD ngokusebenzisa iimvavanyo ze-vitro.

Kulingo lwekliniki olulawulwa ngokungahleliwe olubandakanya abathathi-nxaxheba be-15 kunye ne-NAFLD, i-EGCG idliwe ngamacwecwe e-tea polyphenol, kwaye idatha yesibindi yalinganiswa kwisiseko, iiveki ze-12 kunye neeveki ze-24.

Iziphumo zafumanisa ukuba izigulane zineenqatha eziphantsi kakhulu zesibindi emva kweeveki ze-24 zonyango lwe-EGCG xa kuthelekiswa nesiseko, kwaye izigulane ezimbini zine-fatty remission remission emva kokuphela kweveki ye-24 yonyango. Ukongeza, umjikelezo wesinqe sesigulana kunye namanqanaba e-cholesterol ewonke nawo ehle kakhulu emva kweeveki ezingama-24.

Uhlalutyo lubonise ukuba emva kweeveki ze-24 zonyango lwe-EGCG, amanqanaba e-AST ancitshiswa kwaye amanqanaba e-DPP4 nawo ancitshiswa.

Uhlalutyo lomsebenzi wezintso lubonise ukuba amanqanaba e-serum creatinine kunye namaxabiso e-glomerular filtration rate ahlala ngaphakathi kwinqanaba eliqhelekileyo, ebonisa ukuba i-EGCG ineprofayili yokhuseleko oluhle.