Kwasebutsheni be-1930s, izazinzulu zafumanisa ukuba ukukhanya kwelanga okanye ukusetyenziswa kweoyile yomnquma, ioyile yeflaxseed, kunye nokunye ukutya okunokukhanya kwe-UV kunokulwa ne-osteoporosis. Uphando olongezelelekileyo ngoososayensi bachonge kwaye babiza ivithamin D njengesithako esisebenzayo kumzimba womntu ukulwa neosteoporosis.

I-Vitamin D (i-VD ngokufutshane) yivithamin enyibilikayo ngamanqatha, liqela lezinto eziphuma kwi-steroid ezineziphumo ze-anti rickets kunye nezakhiwo ezifanayo. Eyona nto ibalulekileyo yi-vitamin D3 (cholecalciferol, cholecalciferol) kunye ne-vitamin D2 (calciferol). I-Vitamin D ekutyeni ikakhulu ivela kwizilwanyana ezisekelwe kwizilwanyana ezifana nesibindi sentlanzi, i-yolk yeqanda, ibhotela, njl. Emva kokungeniswa, ifunxelwa emathunjini amancinci phambi kwe-bile kwaye ihanjiswe kwigazi ngendlela ye-chylomicrons. Iguqulwa ibe yi-1,25-dihydroxyvitamin D3 ngesibindi, intso, kunye ne-mitochondrial hydroxylase, enomsebenzi we-biological kwaye inokukhuthaza ukuhlanganiswa kweprotheni ebopha i-calcium (i-CaBP) kwi-intestinal mucosa, ikhuthaza ukuxutywa kwe-calcium, kunye nokukhuthaza ukubala kwamathambo. I-7-dehydrocholesterol, i-cholesterol derivative emzimbeni womntu, igcinwe ngaphantsi kwe-subcutaneous kwaye inokuguqulwa ibe yi-cholecalciferol phantsi kokukhanya kwelanga okanye imisebe ye-ultraviolet. Yi-vitamin D engapheliyo ekhuthaza ukufunxa kwe-calcium kunye ne-phosphorus.

I-VD iphuma kwi-steroids. I-crystal emhlophe, i-soluble in fat, eneempawu ezizinzile, ukumelana nokushisa okuphezulu, i-antioxidant, ayinakumelana ne-asidi kunye ne-alkali, kwaye inokutshatyalaliswa ngokubola kwe-fatty acid. Isibindi sezilwanyana, ioli yesibindi sentlanzi, kunye neqanda leqanda zizityebi kumxholo. Imfuneko yemihla ngemihla kwiintsana, abantwana, abaselula, abafazi abakhulelweyo, kunye noomama abancancisayo yi-400 IU (iiyunithi zamazwe ngamazwe). Xa kungabikho, abantu abadala batyekele kwi-osteomalacia, kwaye abantwana badla ngokuba ne-rickets. Ukuba i-calcium yegazi iyancipha, kunokubakho ukuxubha kwezandla kunye neenyawo, ukuxubha, njl., Okukwahambelana nokuphuhliswa kwamazinyo. Ukutya kakhulu kwe-vitamin D kunokubangela i-calcium ephezulu yegazi, ukulahlekelwa ngumdla, ukuhlanza, isifo sohudo, kunye ne-ectopic ossification yezicubu ezithambileyo.