Iziphumo zophononongo olunesihloko esithi iVithamin D ilawula ukunganyangeki komhlaza oxhomekeke kwi-microbiome zapapashwa kwijenali yeSayensi ngo-Epreli 26, 2024: Amanqanaba asezantsi evithamin D emzimbeni womntu anxulunyaniswa nophuhliso lwethumba, kwaye ivithamin D inokuba yeyona nto iphambili ekuthinteleni nasekunyangelweni kwethumba.

1.Yintoni imisebenzi yevithamini D?

Uphononongo kwiBritish Medical Journal lubonise ukuba ukuxhaswa kwe-vitamin D kunciphisa umngcipheko wezifo ezizimele ngama-22 ekhulwini. Ngamanye amazwi, ukuqinisekisa ukuba ivithamin D eyaneleyo ifanelekile kulawulo lomzimba.

Ukongezelela, uphando lufumene ukuba amanqanaba e-vitamin D e-plasma ahambelana ngokuphambene nomngcipheko womhlaza kwaye unokunciphisa umngcipheko womhlaza; I-Vitamin D inokulawula uxinzelelo lwegazi kunye nokuphucula ukusebenza kwentliziyo; Ukuphucula ukulala, ukunciphisa umngcipheko wesifo sikashukela, njl.

Amathambo awomeleleyo: I-Vitamin D sisondlo esibalulekileyo sokugcina amathambo enempilo. Ikhuthaza ukufunxwa kwe-calcium kunye nenkqubo ye-mineralization yamathambo, ukwandisa ukuxinana kwamathambo kunye nokwenza amathambo omelele. Oku kubaluleke kakhulu kuthintelo kunye nokunyangwa kwezifo zamathambo ezifana ne-rickets kunye ne-osteoporosis.

Ukulawulwa kwamajoni omzimba: I-Vitamin D ibalulekile ekusebenzeni okufanelekileyo kwamajoni omzimba. Iyakwazi ukulawula umsebenzi kunye nenani leeseli zomzimba, ukwandisa ukuxhathisa komzimba kwiintsholongwane, iibhaktheriya kunye nezinye iintsholongwane, kunye nokuthintela ukwenzeka kwezifo.

Uthintelo lomhlaza kunye nonyango: IVithamin D inxulumene ngokungafaniyo nomngcipheko wokuphuhlisa iintlobo ezininzi zamathumba. Abantu abanamanqanaba aphezulu e-plasma kavithamini D banomngcipheko omncinci wokuba nomhlaza onje ngebele, i-colorectal, isibindi, isinyi kunye nomhlaza wemiphunga. I-Vitamin D yenza imiphumo yokuchasana ne-tumor ngeendlela ezahlukeneyo, kubandakanywa ukuvimbela ukwanda kweeseli, ukukhuthaza i-cell apoptosis, ukulawula ukusebenza kwe-immune, kunye nokuvimbela i-tumor angiogenesis. Ngoko ke, i-vitamin D inokuba yinto ephambili ekuthinteleni i-tumor kunye nonyango.

Ukulawula uxinzelelo lwegazi kunye nokuphucula umsebenzi wentliziyo: I-Vitamin D nayo idlala indima ebalulekileyo ekulawuleni uxinzelelo lwegazi kunye nokuphucula ukusebenza kwentliziyo. Inokuchaphazela ukwanda kunye nokuhlukana kweeseli ze-vascular smooth muscle, ngaloo ndlela ilawula ithoni ye-vascular kunye nokunciphisa uxinzelelo lwegazi. Ukongezelela, i-vitamin D iphucula umsebenzi we-contractile we-muscle yenhliziyo kunye nokunciphisa umngcipheko wesifo senhliziyo.

Ukuphucula ukulala nokunciphisa ingozi yesifo seswekile: Ivithamin D inokukhuthaza ukuveliswa kwe-insulin kunye nokusetyenziswa komzimba kwe-insulin, inceda ukugcina iswekile esegazini izinzile kwaye inciphisa ingozi yesifo seswekile. Kwangaxeshanye, inokulawula i-nerve yengqondo, ikhuthaze ubuthongo, iphucule umgangatho wokulala.

2.Zeziphi izigulana ezinomhlaza ekufuneka zithathe izongezo zevithamini D?

Ingxaki yokunqongophala kwevithamin D ixhaphakile kubantu baseTshayina, kwaye kwizigulana ezinomhlaza, le ngxaki ibonakala ngakumbi.

Kwizigulane eziphathwa ngamachiza ehomoni okanye i-aromatase inhibitors: Ukufunxa i-Vitamin D kwezi zigulana kunokuchaphazeleka. Izigulana zithandwa kakhulu kukunqongophala kwe-vitamin D, nto leyo eyenza buthathaka ngakumbi umsebenzi wokuzivikela kunye nokwandisa iingxaki ezifana nesifo se-metabolic syndrome kunye ne-osteoporosis. Ngoko ke, ezi zigulana kufuneka zihlawule ngakumbi ukuxhaswa kwe-vitamin D.

Izigulana ezinomhlaza wepancreatic, isibindi kunye ne-bile duct ezinxulumene nomhlaza: Ukufunxwa kweVitamin D kwezi zigulana kunokuchaphazeleka. Izigulane emva kokuhlinzwa kwe-thyroid nazo kufuneka zihlawule ingqalelo kwi-vitamin D yokuncedisa. Ekubeni i-hypoparathyroidism ingenzeka emva kokuhlinzwa, okubangela ukuphazamiseka kwe-calcium kunye ne-phosphorus metabolism, kubalulekile ukubeka iliso kwi-calcium kunye ne-vitamin D emva kokuhlinzwa.

Izigulana ezinomhlaza eziphucukileyo: Kananjalo kufuneka zithathele ingqalelo izongezo zevithamini D. Ngenxa yokuba izigulana ezinomhlaza ophezulu zihlala zinengxaki yokungondleki kunye nokuphazamiseka kwemetabolism ezininzi, ukongezwa kwe-vitamin D kubalulekile.