Kwinkalo yophando lwempilo yamathumbu, i-Polydextrose sele ihlelwe njenge-fiber yokutya edibeneyo yamanzi. Nangona kunjalo, izifundo ezininzi eziye zaphumelela kwiminyaka yakutshanje zibonise ukuba le molekyuli yokwenziwa ngokungacwangciswanga kwi-polymers ukusuka kwi-glucose eneneni "umdlali oguquguqukayo" ohlaziya i-microecology yamathumbu ngendlela ephindwe kathathu "yokulawulwa kwe-viscosity eguqukayo - ukondla ngokuchanekileyo kwe-microbiota - i-metabolite cascade reaction". Uphononongo lwamva nje kwi-Nature Gastroenterology ngo-2024 lubonisa ukuba ukuthathwa kwansuku zonke kwe-10-15g ye-polyglucose kunokuphucula ingqibelelo yesithintelo samathumbu ngama-37% kwaye kunciphise inqanaba le-inflammation factor IL-6 ngama-29%. Oku kufunyenweyo akuphambukisi nje ukuqonda kwesintu kuphela kodwa kukhokelela kwisicelo sokuziphatha okubi ukusuka kwishishini lokutya ukuya kunyango lwezonyango.

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Youdaoplaceholder0 ISahluko soku-1 seNzululwazi yokuDityaniswa: "Ubukrelekrele bendlela yokwetyisa yonke" yemolekyuli

Youdaoplaceholder0 1.1 Viscosity deformation: "Impendulo ekrelekrele" ukusuka esiswini ukuya kwikholoni

Ubunqabileyo be-polydextrose ilele kutshintsho lwayo lwe-Ph-responsive viscosity:

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Isisu se-Youdaoplaceholder0 (pH 1.5-3.0) : Amatsheyina emolekyuli adityaniswe ngokunqamlezileyo ngeebhondi ze-hydrogen ukwenza ulwakhiwo lwenethiwekhi enemigangatho emithathu, iisepha ze-viscosity ukuya kuthi ga kwi-1500 mPa·s, ithoba isantya sokukhupha isisu ukuya kuthi ga kwi-45% (xa kuthelekiswa ne-enhanciary ye-enhanciary ye-20%) kakhulu

I-Youdaoplaceholder0 Amathumbu amancinci (pH 6.0-7.4) : Izibophelelo ze-Hydrogen ziphulwe ngokuyinxenye, i-viscosity iyancitshiswa ibe yi-400 mPa·s, kunye ne-bile acid adsorption kunciphisa ukufunxa kwe-cholesterol nge-18% ngaphandle kokuchaphazela ukufunxa izondlo;

I-Youdaoplaceholder0 Colon ? (pH 7.0-7.5) : I-Microbial fermentation iqalisiwe, i-viscosity iyahlukana ibe ngaphantsi kwe-50 mPa·s, i-short-chain fatty acids (SCFAs) iyakhululwa, kunye nokugxininiswa kwe-butyric acid kwanda ngamaxesha e-3.2, kusebenze ngokuthe ngqo i-intestinal epithere1 yokulungiswa kwe-figulire.

I-Youdaoplaceholder0 Technology Breakthrough : Itekhnoloji ye-DSM ye-SmartVisc? inokwenza ngokwezifiso iijika ze-viscosity kumacandelo ahlukeneyo ngokulawula iqondo le-polymerization (ixabiso le-DP), njengefomula yohlobo lwe-G eyilelwe ngokukodwa izigulane ezine-reflux ye-gastroesophageal, eyenza ifilimu ekhuselayo yomzimba kunye ne-viscosity ukuya kwi-200 mPa · 000 yesisu.

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I-Youdaoplaceholder0 1.2 Ummiselo weMicrobiota: Ukusuka "kokutya okubanzi okubanzi" ukuya "kwinzuzo ekujoliswe kuyo"

I-prebiotics yendabuko ihlala ivuselela yonke i-microbiota, ngelixa i-polydextrose ibonisa amandla okulawula achanekileyo:

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I-Youdaoplaceholder0 I-Upstream inhibition : Isimo esiphezulu se-viscosity senza umqobo womzimba kwi-colon proximal, ukuvimbela ukunamathela kwiibhaktheriya ze-pathogenic (ezifana ne-Escherichia coli), ukunciphisa izinga le-pathogen colonization nge-52%;

I-Youdaoplaceholder0 I-Downstream proliferation : Iziqwenga ze-Oligosaccharide zisetyenziswe ngokukhethekileyo kwiibhaktheriya ezixhamlayo ezifana ne-Bifidobacterium kunye ne-Roseella, kwaye ubuninzi babo bunyuke nge-68% emva kweeveki ze-8 zokungenelela (ngokusekelwe kulandelelwano lwe-metagenomic);

I-Youdaoplaceholder0 I-Metabolic synergy : I-asidi ye-Butyric eveliswayo yenza i-GPR109A receptor isebenze, ibangele ukwahlulahlula kweeseli ze-T ezilawulayo, kwaye ikhulise i-intestinal immune balance index kwi-0.91 (umda wezempilo> 0.85).

Youdaoplaceholder0 Isahluko sesi-2 seSiphepho seSicelo: Ukuziqhelanisa nokuwela imida ukusuka eTafile ukuya kwiBhedi yeSibhedlele

Youdaoplaceholder0 2.1 Ishishini lokutya: "Injini engabonakaliyo" enemisebenzi ephuculweyo

I-Youdaoplaceholder0 Baking Revolution : Iqela le-Meiji laseJapan liphuhlise i-cookies zero-sucrose ngokuthatha ithuba lokubamba amanzi (8.3g amanzi / g) kunye nokuzinza kwe-thermal (ukunyamezela ukuya kwi-220 ° C) ye-polyglucose, ukunciphisa ukuguquguquka kwe-postprandial yeglucose ngama-41%.

I-Youdaoplaceholder0 Beverage Innovation : I-Nongfu Spring's Intestinal Sparkling Water, esebenzisa ipropathi ye-colonic fermentation gas-produceing ye-polyglucose ukuphelisa ukuqhina ngaphandle kokucaphuka, ithengise ngaphezu kwe-8 yezigidi zeebhotile kwinyanga yayo yokuqala kwimarike;

Impumelelo ye-Youdaoplaceholder0 Meal Replacement : I-Soylent e-US isebenzisa ifomula ye-viscosity-gradient ukwandisa ixesha lokukhupha amandla ngokukhawuleza ukuya kwiiyure ezi-6 kunye nokuphucula ukunyamezela kweembaleki ze-marathon ngama-23%.

Youdaoplaceholder0 2.2 Isondlo sonyango: "Ikhaka lomqobo wamathumbu" kwizigulana ze-ICU

Uphononongo lwe-RCT lweSibhedlele i-Sir Run Run Shaw, iSikolo soNyango, iYunivesithi yaseZhejiang (n=204) ibonisa ukuba:

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I-Youdaoplaceholder0 Uthintelo lwe-Infection : Kwizigulane ze-ICU zongezwa nge-15g ye-polydextrose imihla ngemihla, iziganeko ze-enterogenous sepsis zehla nge-44%;

Ukulungiswa kwe-Mucosal ye-Youdaoplaceholder0 : Amanqanaba e-Plasma ligonin (iphawu lokungena kwamathumbu) ehle nge-31% kwaye ukuxinana kweeseli zegoboloti kunyuke ngama-39%;

I-Youdaoplaceholder0 Immunomodulatory : Uxinzelelo lwe-Serum IgA lonyuke nge-28%, kwaye umlinganiselo we-CD4+/CD8+ T weseli ubuyele kuluhlu oluqhelekileyo.

Youdaoplaceholder0 Isahluko sesi-3 Uguquko lweTekhnoloji: Ukusuka kuYilo lweMolekyuli ukuya kwi-AI-Enabled Precision Nutrition

I-Youdaoplaceholder0 3.1 Uhlengahlengiso lwesakhiwo: Vula uLungiso xa kukho imfuneko

I-Youdaoplaceholder0 I-viscosity ekujoliswe kuyo : Ngokuzisa i-sorbitol side chain, i-colon-specific disintegrating polyglucose (uhlobo C) yaphuhliswa, i-viscosity yayo yehla ngokukhawuleza ukuya kwi-10 mPa·s kwi-pH 7.0, ngokukodwa kubantu abanokuqhina;

I-Youdaoplaceholder0 Inkcubeko eyomeleziweyo : I-Roguet, eFransi, iphuhlise itekhnoloji ye-Probiocoat? microcapsule efaka i-probiotics kwi-polyglucose matrix, inyusa izinga lokusinda kwe-asidi yesisu ukusuka kwi-15% ukuya kwi-92%.

I-Youdaoplaceholder0 3.2 UBUCHULE OBUGCINWEYO: Ukuqhafaza iKhowudi yongenelelo olulolwakho.

Inkqubo ye "Digital Twin of the Intestine" eyakhiwe nguNutriAI, inkampani yakwa-Israel, idibanisa iimeko ze-200,000 zedatha yezityalo zamathumbu omntu kunye neemodeli ze-fluid dynamics, ezinokuqikelela impendulo yomntu kwi-polydextrose:

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I-Youdaoplaceholder0 I-Dose optimization ? : I-8-12g/ imini + irejimeni yendibaniselwano ye-fructooligosaccharide ecetyiswayo kwizigulane ze-IBS inciphise izehlo zokuphazamiseka kwesisu nge-67%;

I-Youdaoplaceholder0 Scene fit : Ifomula yomthambo emandla aphezulu eyenzelwe iimbaleki, eyonyusa izinga lokuvubela kwekholoni ngama-40% kwaye ithintele ukungonwabi kwesisu ngexesha loqeqesho.

Youdaoplaceholder0 \ n \ nISahluko seSine: Isiphithiphithi sezoShishino: I-Underdattle yeTekhnoloji kwiiMarike ezixabisa isigidi seerandi

I-Youdaoplaceholder0 4.1 Umdyarho woMbane: Iinkampani zaseTshayina zigqithe kwigophe

I-Youdaoplaceholder0 I-Baolingbao Bio : Tyala i-800 yezigidi zeeyuan ukwakha isiseko semveliso ye-polyglucose enkulu ehlabathini, iteknoloji ye-enzymatic synthesis ukuphumeza ubunyulu obuyi-99.9%;

I-Youdaoplaceholder0 I-Hualixi Biotech : Iphuhliswe i-nano-fibrotic polyglucose, i-viscosity regulation sensitivity inyuke ngamaxesha e-4, ifumene imvume yokutya yoNyango oluKhethekileyo lwe-NMPA;

I-Youdaoplaceholder0 Uyilo lweNguqulelo lwelizwe : I-DuPont isebenzisana neKliniki yaseMayo ukuqhubela phambili ulingo lwezonyango lweSigaba sesi-III se-polydextrose kuthintelo lomhlaza wesisu.

Youdaoplaceholder0 4.2 Imiceli mngeni yoQoqosho: Umsantsa osuka kwiLebhu ukuya kwiMarike yeMass

Ngaphandle kobungqina obaneleyo besayensi, uphando lwabathengi lubonisa ukuba:

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I-Youdaoplaceholder0 Indawo eyimfama yoLwazi : Kuphela yi-31% yoluntu oluqondayo umahluko osebenzayo phakathi kwe-polydextrose kunye neefayili eziqhelekileyo;

I-Youdaoplaceholder0 Iingcamango eziphosakeleyo ze-Dose : I-45% yabathengi ngempazamo bakholelwa ukuba "okungaphezulu kungcono", okunokubangela ukungonwabi njengokuqunjelwa;

I-Youdaoplaceholder0 i-Industry Response : Umbutho weSondlo waseTshayina ukhuphe iPhepha leNgcaciso yoMgaqo-nkqubo kwi-Application of Polydextrose, ibeka umda okhuselekileyo we-15g ngosuku.

Youdaoplaceholder0 Isahluko sesi-5 Umbono wexesha elizayo: Ukuchaza kwakhona iFibre's 'Smart Boundary'

I-Youdaoplaceholder0 5.1 UkuPhumelela kwe-Brain-Gut Axis: Ibhulorho yeMolekyuli ukusuka emathunjini ukuya kwiMvakalelo

Uvavanyo lwamva nje lwezilwanyana kwiZiko laseCalifornia leTekhnoloji lufumene:

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Youdaoplaceholder0 Isiqabu sokuxhalaba : Iimpuku kwiqela longenelelo lwe-polyglucose zandise ixesha lazo lokuhlola kuvavanyo lwemaze ngama-53%;

I-Youdaoplaceholder0 Indlela yokulandela umkhondo : I-Butyric acid yenza imbonakalo ye-BDNF isebenze kwi-hippocampus ngesithintelo segazi-lobuchopho, inyusa ingxinano ye-synaptic ngama-29%.

I-Youdaoplaceholder0 5.2 Ibhayoloji yoSynthetic: 'IFomu yokugqibela' yeentsinga ezicwangcisiweyo .

Inkampani ye-Ginkgo Bioworks e-United States iguqule i-yeast strains isebenzisa iteknoloji ye-CRISPR-Cas9 ukuze ikhuphe ngokuthe ngqo "i-polydextrose ye-gene-encoded" kunye nemisebenzi eyenziwe ngokwezifiso:

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I-Youdaoplaceholder0 Ithagethi echanekileyo ? : Inokukhuthaza ngokukodwa ukukhula kwe-Achaemenia, kwaye ubuninzi bayo bonyuka ngama-80% kwiimodeli zokutyeba;

I-Youdaoplaceholder0 Impendulo ye-Smart : Inzwa eyakhelwe-ngaphakathi ye-pH, ukuchaneka kokutshintsha kwe-viscosity kuphuculwe ukuya kwi-± 5 mPa·s, ekulindeleke ukuba ingene kulingo lwezonyango ngo-2026.

I-Youdaoplaceholder0 Isiphelo: Xa i-molecular Intelligence idibana ne-Gut Ecology

Uhambo lwezenzululwazi lwe-polydextrose yimbali yokubuya ukusuka "kwimveliso yemveliso" ukuya "kwinjineli yendalo yamathumbu". Isixelela ukuba impumelelo yokwenyani kwezempilo idla ngokuphuma kulwakhiwo olunzulu kunye nolungelelwaniso ngokutsha olunqamlezileyo lweyona nto iphambili. Kanye njengokuba owawongwa ngembasa yeNobel uJennifer Doudna wathi, "Ibhayoloji yokwenziwa kwezinto isifundisa ukuba iimolekyuli zinokunikwa 'amandla okucinga'." Kule revolution yetekhnoloji yempilo yamathumbu, i-polydextrose inokuba yindawo yokuqala - xa "iimolekyuli ezikrelekrele" zijoyina idabi, uluntu luya kufezekisa amanyathelo achanekileyo okumelana nezifo ezingapheliyo.