I-Vitamin B12 ikwabizwa ngokuba yiHydroxycobalamin

Qhagamshelana nathi

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Intshayelelo

I-Hydroxycobalamin (ohcbl, okanye i-B12a) luhlobo lwendalo lwe-vitamin B12, okanye enye yeeklasi ze-vitamin B12. Lilungu elisisiseko leqela le-cobalamine. Uninzi lweebhaktheriya ezivelisa iivithamini ngokurhweba zivelisa i-vitamin B12 ngendlela ye-hydroxycobalamin. IHydroxycobalamin ibomvu bumnyama. I-Vitamin B12 emzimbeni womntu ayiqhelekanga ukuba ibekho ngendlela ye-hydroxycobalamin. Nangona kunjalo, ebantwini, i-hydroxycobalamin iguqulwa ngokulula ibe yifom ye-coenzyme eluncedo ye-vitamin B12. Imveliso ye-hydroxycobalamin yeyeza yinaliti yayo eyinyumba, esetyenziselwa ukunyanga ukunqongophala kwevithamini kunye netyhefu ye-cyanide (kuba iyahambelana ne-cyanide ion). IHydroxycobalamin nayo isetyenziswa njenge scavenger..

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Umsebenzi

Okwangoku, kukho iintlobo ezine zevithamini B12 kwimarike yehlabathi ye-API. Ziyi-hydroxycobalamin, i-Mecobalamin, i-cyanobalamin kunye ne-cobalamin adenosine. Oku kungenxa yokuba i-ion ephakathi kwi-molecule ye-B12 inamaqela ahlukeneyo asebenzayo, ngoko ibizwa ngokuba ngamagama ahlukeneyo. IHydroxycobalamin ibizwa ngokuba yi-hydroxycobalamin kuba i-ion ephakathi ye-B12 idityaniswe neqela le-hydroxyl. Phakathi kweeamolekyuli ezine ze-B12, i-hydroxycobalamin ine-solubility engcono yamanzi kunye ne-metabolism ecothayo kumchamo, owaziwa ngokuba yi-cobalamin esebenza ixesha elide. Nangona izinga lokufunxa alinakuthelekiswa nelo le-cyanocobalan kunye ne-Mecobalamin, ukugxilwa kwayo kwiso kuphezulu kakhulu, okunokuthi kunciphise kakhulu ukukhathala okubonakalayo kunye nokondla i-nerve optic. Ngoko ke, inefuthe elithile lokunyanga kwi-amblyopia ebangelwa yityhefu. Ukongeza, i-hydroxycobalamin inokudibanisa ngokukhawuleza kunye ne-cyanide yasimahla ukwenza i-cyanobalamin engenatyhefu kwisisombululo esinamanzi, ngoko ke esinye isiphumo sayo sonyango sisithintelo setyhefu yecyanide.

Ukuchazwa kwemveliso

Izinto	Imigangatho	Iziphumo
Uhlalutyo lomzimba kunye neekhemikhali
Imbonakalo	Ubomvu ophaphathekileyo ukuya kumgubo omdaka ihygroscopicity	Iyahambelana
Ukuchongwa	Yiba nokufunxa okuphezulu kwi-361±1nm,550±2nm	Iyahambelana
Ilahleko ekomisweni	≤12%	9.0%
Isivavanyi	09.0%-1.3%	1%
Intsalela ekutshisweni	≤0.1%	0.06%
Intsimbi enzima
Arsenic(As)	≤0.1mg/kg	Iyahambelana
Khokela(Pb)	≤1mg/kg	Iyahambelana
Iimvavanyo zeMicrobiological
Ukubalwa kwePleti iyonke	≤1000cfu/g	Iyahambelana
Umngundo kunye negwele	≤100cfu/g	Iyahambelana
I-Coliform	Ibi	Ibi
E.coli	Ibi	Ibi
Salmonella	Ibi	Ibi
Staphylococcus	Ibi	Ibi
Iinkcukacha zajikelele
Iphakheji: 25kg / ibhokisi
Ugcino: Imveliso kufuneka igcinwe kwindawo eyomileyo nepholileyo, kwaye ithintele ukufuma, ukukhanya kwelanga, ukuqhambuka kwezinambuzane, ukungcoliseka kwezinto ezinobungozi kunye nomnye umonakalo.
Beka ubomi kwishelufa	Iminyaka emi-3